Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,816
Medical Information Manager, Vaccines
$110K - $130K *
Help us ensure the delivery of scientifically balanced medical information that supports clinical care and formulary access decisions, while collaborating with key stakeholders to enhance product unde...
Yesterday
Sr. AI Product Manager – Market Access
$130K - $155K *
Lead the charge in leveraging AI to enhance commercial outcomes across Market Access, integrating technology with business strategy to drive measurable impact and innovation in account management, pri...
Yesterday
TBO - Change, Comms. & OCM Manager
$110K - $130K *
Drive impactful organizational change and communication strategies, ensuring effective governance and adoption across teams. Lead transformation initiatives, fostering collaboration and readiness whil...
Yesterday
Senior Manager, Product Management – Field Intelligence
$130K - $155K *
Unlock your potential as a Senior Manager in Product Management, leading the technology strategy and roadmap for a unified Field Intelligence platform. Drive innovation and enhance decision-making thr...
Yesterday
$95K - $115K *
Empower cross-functional teams to define and deliver digital product profiles and recipe libraries, ensuring seamless integration and usability across systems while driving innovation in product devel...
Yesterday
Senior Manager, Product Management – Core CRM
$120K - $145K *
Engineer the future of CRM technology by leading the strategy, architecture, and lifecycle management of a cutting-edge platform that enhances customer engagement and operational excellence across com...
Yesterday
Manager, Health Informatics (Southeast)
$152K - $253K *
Transform healthcare delivery by leveraging health information technology to enhance patient care and operational efficiency. Collaborate with health systems and cross-functional teams to align techno...
Yesterday
ViiV Healthcare (GSK) Senior Manager, US Enterprise Communications
$110K - $130K *
Elevate enterprise communications by developing and executing strategies that align with business objectives, ensuring consistent messaging across channels while engaging key stakeholders in a dynamic...
Yesterday
Director, Global Content Design and Delivery, Oncology
$187K - $312K *
Drive the development of Integrated Medical Communication Plans in Oncology, leading cross-functional teams to create scientifically accurate content and innovative communication strategies for health...
Yesterday
Associate Director, Global Epidemiology and Real-World Evidence
$149K - $248K *
Drive epidemiology initiatives that influence patient outcomes by designing and delivering real-world studies. Collaborate with cross-functional teams to ensure high-quality evidence generation and im...
Yesterday
Sr. AI Product Manager – Market Access
$138K - $165K *
Shape the future of AI in Market Access by leading cross-functional teams to deliver impactful solutions. Drive end-to-end delivery from discovery to deployment, ensuring responsible AI use and measur...
Yesterday
Dir. Product Manager, Digital & Growth AI Tech
$150K - $180K *
Innovate AI-driven growth strategies to enhance HCP and patient outcomes across the commercial funnel. Lead cross-functional teams to implement generative AI solutions, ensuring compliance and measura...
Yesterday
Senior AI Product Manager – Government Pricing & Compliance
$130K - $155K *
Explore your career by leading AI-driven solutions for government pricing and compliance. Collaborate across teams to enhance accuracy, optimize systems, and ensure regulatory adherence while managing...
Yesterday
Clinical Pharmacist - Value Based Care
$110K - $130K *
Unlock potential by leading a remote pharmacy program focused on medication adherence. Collaborate with a specialized team to enhance patient care through data-driven strategies and operational suppor...
Yesterday
Senior Compensation Consultant
$110K - $130K *
Lead complex compensation initiatives, ensuring equitable pay programs while managing projects. Serve as a subject matter expert in various compensation areas and collaborate with teams to enhance org...
Reposted yesterday
Workers' Compensation Claims Specialist - Alternative Markets
$90K - $110K *
Unlock potential by joining a dynamic team as a Workers’ Compensation Claims Specialist. Leverage your expertise to investigate, resolve, and manage claims while ensuring compliance and delivering exc...
Reposted yesterday
Senior Product Analyst - Employer Health Solutions
$79K - $125K *
Lead the charge in enhancing Employer Health Solutions products, driving market competitiveness through collaboration, strategic analysis, and innovative development. Support regulatory compliance and...
Reposted yesterday
Senior Business Intelligence Analyst - Enterprise Analytics
$90K - $115K *
Lead the charge in transforming complex business needs into impactful analytic products. Collaborate with stakeholders to design, develop, and maintain reusable semantic models that enhance decision-m...
Yesterday
Senior Commercial Surety Underwriter
$125K - $175K *
Partner with us to assess risk and drive profitability as a Commercial Surety Underwriter. Leverage your expertise to analyze financial reports, make informed decisions, and build strategic relationsh...
Reposted yesterday
$81K - $126K *
Drive the financial and administrative operations of a department, overseeing budgeting, procurement, and staff management. Empower teams to enhance efficiency and compliance while ensuring effective...
Yesterday
$75K - $90K *
Elevate your career by leading a dynamic restaurant team, driving sales growth, and ensuring exceptional customer experiences. This role demands hands-on leadership and a commitment to quality in a fa...
Yesterday
$180K - $220K *
Lead the global Accounting and Treasury function, driving financial systems, reporting, and IPO readiness while building a scalable team to support international growth and operational complexity...
Yesterday
$115K - $125K *
Lead the charge in optimizing national operations, ensuring excellence across fulfillment centers. Drive strategic initiatives, enhance client experiences, and foster a culture of continuous improveme...
Yesterday
$165K - $215K *
Champion the evolution of Android features, driving product impact through collaboration and innovation. Own the development process from concept to deployment, ensuring high-quality user experiences...
Yesterday
$160K - $200K *
Join us to redefine retail marketing in the cannabis industry. Lead strategy, visual merchandising, and shopper engagement initiatives to enhance brand presence and drive sales across U.S. dispensarie...
Yesterday
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.