Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,816

Sort By: Relevance

$110K - $130K *

Help us ensure the delivery of scientifically balanced medical information that supports clinical care and formulary access decisions, while collaborating with key stakeholders to enhance product unde...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Lead the charge in leveraging AI to enhance commercial outcomes across Market Access, integrating technology with business strategy to drive measurable impact and innovation in account management, pri...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive impactful organizational change and communication strategies, ensuring effective governance and adoption across teams. Lead transformation initiatives, fostering collaboration and readiness whil...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Unlock your potential as a Senior Manager in Product Management, leading the technology strategy and roadmap for a unified Field Intelligence platform. Drive innovation and enhance decision-making thr...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Empower cross-functional teams to define and deliver digital product profiles and recipe libraries, ensuring seamless integration and usability across systems while driving innovation in product devel...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Engineer the future of CRM technology by leading the strategy, architecture, and lifecycle management of a cutting-edge platform that enhances customer engagement and operational excellence across com...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$152K - $253K *

Transform healthcare delivery by leveraging health information technology to enhance patient care and operational efficiency. Collaborate with health systems and cross-functional teams to align techno...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate enterprise communications by developing and executing strategies that align with business objectives, ensuring consistent messaging across channels while engaging key stakeholders in a dynamic...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$187K - $312K *

Drive the development of Integrated Medical Communication Plans in Oncology, leading cross-functional teams to create scientifically accurate content and innovative communication strategies for health...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$149K - $248K *

Drive epidemiology initiatives that influence patient outcomes by designing and delivering real-world studies. Collaborate with cross-functional teams to ensure high-quality evidence generation and im...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$138K - $165K *

Shape the future of AI in Market Access by leading cross-functional teams to deliver impactful solutions. Drive end-to-end delivery from discovery to deployment, ensuring responsible AI use and measur...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Innovate AI-driven growth strategies to enhance HCP and patient outcomes across the commercial funnel. Lead cross-functional teams to implement generative AI solutions, ensuring compliance and measura...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Explore your career by leading AI-driven solutions for government pricing and compliance. Collaborate across teams to enhance accuracy, optimize systems, and ensure regulatory adherence while managing...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by leading a remote pharmacy program focused on medication adherence. Collaborate with a specialized team to enhance patient care through data-driven strategies and operational suppor...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead complex compensation initiatives, ensuring equitable pay programs while managing projects. Serve as a subject matter expert in various compensation areas and collaborate with teams to enhance org...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Unlock potential by joining a dynamic team as a Workers’ Compensation Claims Specialist. Leverage your expertise to investigate, resolve, and manage claims while ensuring compliance and delivering exc...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$79K - $125K *

Lead the charge in enhancing Employer Health Solutions products, driving market competitiveness through collaboration, strategic analysis, and innovative development. Support regulatory compliance and...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $115K *

Lead the charge in transforming complex business needs into impactful analytic products. Collaborate with stakeholders to design, develop, and maintain reusable semantic models that enhance decision-m...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $175K *

Partner with us to assess risk and drive profitability as a Commercial Surety Underwriter. Leverage your expertise to analyze financial reports, make informed decisions, and build strategic relationsh...

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $126K *

Drive the financial and administrative operations of a department, overseeing budgeting, procurement, and staff management. Empower teams to enhance efficiency and compliance while ensuring effective...

Yesterday

  •   Less than 5 years exp.  •   Transportation

$75K - $90K *

Elevate your career by leading a dynamic restaurant team, driving sales growth, and ensuring exceptional customer experiences. This role demands hands-on leadership and a commitment to quality in a fa...

Yesterday

  •   Less than 5 years exp.  •   Food & Beverages

$180K - $220K *

Lead the global Accounting and Treasury function, driving financial systems, reporting, and IPO readiness while building a scalable team to support international growth and operational complexity...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$115K - $125K *

Lead the charge in optimizing national operations, ensuring excellence across fulfillment centers. Drive strategic initiatives, enhance client experiences, and foster a culture of continuous improveme...

Yesterday

  •   5 - 7 years exp.  •   Business Services

$165K - $215K *

Champion the evolution of Android features, driving product impact through collaboration and innovation. Own the development process from concept to deployment, ensuring high-quality user experiences...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Media

$160K - $200K *

Join us to redefine retail marketing in the cannabis industry. Lead strategy, visual merchandising, and shopper engagement initiatives to enhance brand presence and drive sales across U.S. dispensarie...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.