Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,677

Sort By: Relevance

$85K - $100K *

Join a dynamic team to oversee clinical operations, manage multidisciplinary staff, and ensure quality control in vascular imaging. Drive program development and enhance patient care through effective...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Unlock strategic labor counsel by leading collective bargaining and advising management on union-related challenges in a high-impact, remote setting. Drive successful negotiations and navigate complex...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Transportation

$80K - $150K *

Transform your career by leading complex DeltaV Batch automation projects. Drive design, commissioning, and support phases while collaborating with cross-functional teams to ensure successful project...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$141K - $220K *

Drive quality improvements across APM manufacturing sites by leading initiatives, partnering with teams, and translating customer needs into actionable plans. Focus on enhancing first-pass quality, re...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$135K - $160K *

Transform client relationships by leading strategic Microsoft initiatives, driving growth, and ensuring satisfaction across multiple accounts. Collaborate with stakeholders to deliver tailored solutio...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$148K - $186K *

Transform your career by serving as a trusted technology advisor, driving digital transformation and cloud adoption for strategic clients. Collaborate with executives to align technology strategies wi...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$135K - $160K *

Drive strategic growth by managing key client relationships and leading Microsoft-focused initiatives. Collaborate with stakeholders to deliver tailored solutions, ensuring client satisfaction and acc...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$148K - $186K *

Shape the future of digital transformation by serving as a trusted technology advisor, aligning innovative strategies with business priorities to drive growth and enhance client relationships across a...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Transform consumer insights into actionable strategies that drive growth across nicotine categories. Leverage data to understand market dynamics, enhance collaboration, and influence decision-making w...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Join a dynamic team as a strategic HR Business Partner, supporting global entities. Drive employee relations, performance management, and culture integration while guiding HR initiatives across divers...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $210K *

Champion innovative growth in surgical sales. Drive digital chest drainage adoption, develop U.S. strategies, and lead a high-performing team to expand market share in a dynamic, evolving environment...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$116K - $160K *

Champion productivity by leading engineering projects that enhance manufacturing processes. Collaborate with cross-functional teams to define, scope, and execute initiatives from concept to implementa...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $175K *

Serve as the key technical expert in managing complex Casualty claims, addressing emerging risks with legal precision and a focus on customer service, while collaborating effectively with stakeholders...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$88K - $105K *

Optimize process control systems to ensure compliance with global standards. Collaborate with local and global teams to enhance equipment reliability and support successful project execution while mai...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Join a dynamic team to drive commercial performance and enhance patient access through strong relationships with healthcare providers, executing strategic business plans and supporting innovative prod...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $192K *

Accelerate progress at the forefront of healthcare by driving commercial performance, building relationships with providers, and ensuring patient access to innovative therapies across a defined territ...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Optimize CNC machining processes by driving efficiency, improving scheduling, and enhancing tool management practices. Become a key player in sustaining continuous improvement, lean initiatives, and r...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $192K *

Discover a pivotal role in driving commercial performance and patient access. Engage healthcare providers, build relationships, and support product launches while collaborating with cross-functional t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $95K *

Lead the charge in developing and maintaining QA programs to ensure compliance with USDA, FDA, and customer standards, enhancing food safety and quality across operations while driving continuous impr...

Charlotte, NCRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $125K *

Shape the future of organizational change by developing strategies, managing transitions, and driving transformation initiatives. Collaborate with teams to enhance productivity and ensure successful i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Elevate the Wood Handling product team by providing technical ownership for chippers and debarking drums. Collaborate globally to enhance product lifecycle, ensuring safety, reliability, and cost-effe...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Empower customer success by serving as the primary technical contact, enhancing solution stability and satisfaction through expert guidance and relationship building in a dynamic, fast-paced environme...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Optimize support processes and lead technical resolutions, mentoring junior team members while collaborating with engineering. Elevate customer experiences by addressing complex issues and enhancing t...

North Carolina, USRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Innovate your career with a key role supporting the global launch and technical operations of radiopharmaceuticals, driving compliance, quality initiatives, and collaboration with CDMOs while leading...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $145K *

Champion government funding strategies by identifying and securing opportunities that align with research priorities. Collaborate with internal teams to translate agency intelligence into actionable p...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.