Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,677

Sort By: Relevance

$83K - $125K *

Engage your career as a key communicator, leading public information initiatives and serving as a spokesperson. Collaborate with media and community partners to enhance public awareness of County prog...

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $150K *

Optimize subcontractor risk management by overseeing prequalification, analyzing financial statements, and enhancing the SDI program. Collaborate with operations to ensure compliance and support proje...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$146K - $225K *

Transform vendor performance and customer satisfaction by leading strategic initiatives across a global BPO network. Drive accountability, analyze data, and collaborate cross-functionally to enhance o...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$176K - $259K *

Inspire high-performing sales teams while driving impactful solutions for mid-sized Public Sector organizations. Utilize coaching, strategic problem-solving, and cross-functional collaboration to fost...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Transform the residency program by providing leadership, education, and high-quality clinical care in diverse pediatric settings. Collaborate with faculty and medical students to enhance training and...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$210K - $235K *

Join a team that's dedicated to transforming oncology sales by building strong relationships with healthcare providers and executing strategic initiatives for a groundbreaking treatment in desmoid tum...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$198K - $292K *

Help us shape the future of autonomous systems by designing and deploying advanced motion planning algorithms for dynamic environments, ensuring safe and efficient navigation in real-time scenarios wh...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$200K - $225K *

Drive the design and delivery of innovative AI-driven applications. Oversee the full development lifecycle, ensuring scalability and reliability in multi-tenant enterprise solutions while collaboratin...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$70K - $110K *

Innovate solutions as you design and execute electrical engineering for manufacturing equipment, ensuring safety and efficiency while collaborating with cross-functional teams to enhance automation an...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$116K - $155K *

Transform the future of healthcare IT by designing scalable, secure database architectures that enhance medical imaging solutions. Collaborate across teams to ensure high-performance systems that supp...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Champion the evolution of our billing systems by leading a dynamic engineering team. Drive strategy, ensure accuracy, and collaborate across departments to enhance customer trust as we scale our usage...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$123K - $165K *

Drive the database architecture strategy for healthcare imaging solutions, leading a high-performing team of engineers. Ensure systems are scalable, secure, and reliable while collaborating with cross...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by driving impactful product launches through cross-functional collaboration and strategic messaging. Engage directly with clients and teams to enhance market presence, adoption, and...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $140K *

Shape the future of cooling technology by developing cost models for large-scale systems. Collaborate with leadership and engineering to optimize pricing strategies, enhance margins, and drive growth...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Unlock potential by driving BioPharma partnership success through innovative liquid biopsy solutions, enhancing clinical trial designs, and fostering key relationships in oncology precision medicine...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$112K - $180K *

Elevate your career by overseeing comprehensive financial operations, ensuring compliance with regulations, and leading a dedicated team. Drive strategic initiatives and enhance financial reporting wh...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Lead the charge in engineering recruiting by shaping hiring strategies, developing a high-performing team, and enhancing scalable processes to support growth while personally managing senior leadershi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Pioneer modern learning experiences by designing impactful training programs and resources. Leverage AI tools for e-learning development and facilitate engaging sessions to drive employee growth and s...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$152K - $179K *

Drive the development of distributed systems for real-time blockchain data ingestion and indexing, owning services from design to production while enhancing performance and reliability across the plat...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Drive growth by developing a profitable employee benefits book, building strategic client relationships, and leveraging extensive carrier partnerships to deliver innovative solutions and exceed revenu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock financial potential by analyzing complex healthcare contracts and data. Collaborate with health systems to translate insights into measurable outcomes, driving operational value and shaping AI...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's shaping the future of education by leading a new classical Christian high school. Drive academic excellence, foster a vibrant community, and cultivate student growth in a faith-cent...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Shape the future of autonomous driving by leading trajectory generation and controls. Collaborate across teams to deliver safe, optimized solutions while enhancing vehicle performance through innovati...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$145K - $175K *

Innovate by designing and delivering advanced data and AI platforms on Databricks. Collaborate with clients and teams to shape solutions, optimize architectures, and drive successful implementations f...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$136K - $217K *

Lead the charge in enhancing public safety through strategic oversight and management of police operations. Collaborate with community stakeholders to ensure effective law enforcement and crime preven...

1 week ago

  •   8 - 10 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.