Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,677

Sort By: Relevance

$90K - $110K *

Champion successful project completion by leading onsite teams, managing operations, and ensuring safety and quality standards are met across multiple construction projects. Collaborate with stakehold...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Unlock your potential by developing innovative control systems for diverse industries. Collaborate with clients to solve complex manufacturing challenges through automation and controls, ensuring effi...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Technical Services

$80K - $83K *

Join our team to develop and implement validation strategies, ensuring compliance with industry standards while collaborating on multiple projects to achieve quality objectives and deliverables...

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$177K - $221K *

Champion regulatory excellence by leading cross-functional teams, ensuring compliance, and driving successful oncology drug development through strategic planning and expert guidance...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $110K *

Elevate sales performance by leading a dynamic team of 20+ in the Carolinas. Drive strategic initiatives, enhance market share, and ensure effective execution of territory plans while fostering a cult...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $100K *

Unlock potential by leading a dynamic team of developers to deliver high-quality software solutions, collaborating with stakeholders, and driving strategic project initiatives while fostering a cultur...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$150K - $190K *

Champion quality assurance excellence in GMP for drug substance and products, overseeing compliance and methodologies. Collaborate to ensure regulatory adherence while maintaining operational efficien...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Information Technology

$109K - $145K *

Contribute to the development of a cloud storage solution, designing and delivering features for a medical imaging platform. Collaborate within an Agile team, taking ownership of the development lifec...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $90K *

Join a dynamic team to drive product marketing and ABM strategies, enhancing customer engagement and market presence through compelling messaging and targeted campaigns that foster growth and awarenes...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Drive exceptional patient care as a Clinical Pharmacist, collaborating with oncology teams to verify chemotherapy orders and support breast cancer patients across multiple locations, ensuring optimal...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $265K *

Champion governance excellence by leading policy frameworks, enhancing Board operations, and driving AI-enabled improvements. Engage with investors and committees to elevate governance practices at a...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$100K - $120K *

Unlock innovative design solutions by collaborating across teams to enhance project outcomes and implement cutting-edge technologies. Drive success through strategic project consultations and elevate...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Empower a transformative digital practice by collaborating with design teams, enhancing client engagements, and driving innovative solutions in architectural design through technology integration and...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$192K - $235K *

Lead analytical development and quality control for sterile parenteral products, ensuring regulatory compliance and successful product launches. Collaborate cross-functionally to establish strategies...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$79K - $118K *

Unlock your potential as a Board Certified Behavior Analyst, delivering tailored, evidence-based care while collaborating with a multidisciplinary team. Enjoy a supportive environment that prioritizes...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$63K - $101K *

Champion the development and implementation of training and quality assurance initiatives, enhancing service delivery and staff performance within Child Protective Services. Lead a team to ensure comp...

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $90K *

Help us lead a dynamic accounting team, overseeing financial operations and ensuring compliance across multiple projects while driving process improvements and fostering collaboration in a remote envi...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

Lead the charge in scaling our Customer Success Management team, driving product adoption and retention across diverse customer segments. Collaborate cross-functionally to create impactful processes a...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$95K - $120K *

Elevate software quality assurance by testing GIS applications and validating complex datasets. Collaborate with developers and GIS specialists to ensure accuracy and reliability in geospatial data fo...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$108K - $131K *

Elevate customer security conversations by bridging Information Security and GTM teams. Utilize AI and automation to streamline processes, enhance resources, and empower teams to confidently address s...

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to delivering innovative architectural solutions. As a Project Manager, you'll lead complex projects, collaborate with clients and team members, and drive design excellenc...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Join a team that's driving customer success by leading a North American Account Management group. You'll enhance retention and growth, develop talent, and shape strategies to maximize revenue and cust...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$102K - $184K *

Optimize content strategies that engage industrial audiences, translating complex technical concepts into compelling narratives. Drive measurable outcomes through high-value content creation, collabor...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$170K - $190K *

Empower innovation at the intersection of technology and law. Guide product, engineering, and compliance teams in navigating regulatory landscapes and mitigating risks related to AI and machine learni...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Information Technology

$79K - $122K *

Empower your career by developing innovative Microsoft 365 solutions. This role involves end-to-end Power Platform development, ensuring compliance, and collaborating with stakeholders to enhance city...

Durham, NCRemote

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.