Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,696
$89K - $115K *
Champion innovative solutions in clinical and patient engagement technologies, leading application analysis, design, and optimization projects to enhance healthcare delivery and streamline user experi...
Reposted 6 days ago
$94K - $121K *
Contribute to the design and implementation of enterprise document management solutions, collaborating with cross-functional teams to enhance system reliability and operational effectiveness while sup...
Reposted 6 days ago
$110K - $130K *
Strategize and execute comprehensive marketing initiatives to enhance brand visibility, drive sales alignment, and leverage AI tools for efficiency. Lead a dynamic team while collaborating closely wit...
6 days ago
Senior Product Manager, Private Cloud Architecture & Ecosystem Strategy
$130K - $155K *
Champion architectural leadership across product lines, driving AI integration and simplifying infrastructure operations. Collaborate with ISV partners to align strategies and enhance ThinkAgile solut...
6 days ago
$95K - $115K *
Accelerate your career by managing multiple internal control audits, leading teams, and driving process improvements. Collaborate cross-functionally to deliver exceptional client service while champio...
6 days ago
$95K - $115K *
Drive excellence in internal controls by managing audits, enhancing processes, and leading a dynamic team. Collaborate across functions to deliver exceptional client service while championing complian...
6 days ago
$110K - $130K *
Transform customer operations by leveraging expertise in supply chain and logistics. Drive process improvements, enhance performance, and deliver measurable results through strategic consulting and co...
6 days ago
$152K - $202K *
Transform organizational effectiveness by leading strategic people initiatives that drive enterprise transformation, enhance workforce readiness, and ensure successful change adoption across cross-fun...
6 days ago
$150K - $180K *
Join a transformative team as an Engineering Manager to lead engineering initiatives, inspire innovation, and drive technical excellence in revolutionizing healthcare technology while fostering profes...
Reposted 6 days ago
OSINT/PAI Targeting Analyst SME
$97K - $132K *
Explore advanced OSINT/PAI targeting analysis, supporting special operations and intelligence assessments. Collaborate with the Intelligence Community to enhance multi-intelligence operations and repo...
6 days ago
$125K - $150K *
Transform product strategy by leading impactful initiatives that enhance user experience and drive growth. Collaborate with cross-functional teams to deliver innovative solutions that delight customer...
6 days ago
$170K - $220K *
Transform program delivery by leading teams and managing client relationships. Drive strategic direction, ensure compliance, and achieve revenue goals while fostering a collaborative, remote-first env...
6 days ago
Senior Product Manager, Lending
$159K - $254K *
Join a team that's redefining financial solutions for restaurants. Lead product innovation in lending, collaborating across departments to enhance our offerings and drive impactful results for restaur...
6 days ago
$80K - $95K *
Join a dynamic team to lead the safe and efficient operation of building systems. Oversee maintenance, manage technicians, and ensure compliance with safety standards while enhancing system reliabilit...
6 days ago
Sr Engineer 1, Automation DSM DeltaV Infrastructure
$110K - $130K *
Lead the Automation team in enhancing Drug Substance Manufacturing systems. Drive complex projects, collaborate across departments, and ensure compliance while providing on-call support and training t...
6 days ago
DevOps Engineer - US East Coast/ Central
$120K - $145K *
Architect and enhance scalable infrastructure and CI/CD pipelines, collaborating across engineering teams to implement innovative cloud technologies and open-source solutions for optimal product deliv...
6 days ago
$110K - $130K *
Take ownership of our NetSuite environment by developing and automating solutions that enhance efficiency across Finance, Sales, and Operations. Collaborate with stakeholders to implement AI-driven fe...
6 days ago
RN Clinical Nurse II - 6 Childrens Acute Care Medicine Unit
$71K - $100K *
Transform pediatric care by delivering compassionate nursing in a dynamic unit. Collaborate with a dedicated team to provide high-quality care for children with complex health needs, ensuring a suppor...
6 days ago
$123K - $180K *
Join a team that's dedicated to enhancing the 340B Drug Pricing Program through strategic leadership, compliance, and operational excellence across a multi-entity health system, ensuring program integ...
6 days ago
2LOD Director of AI Risk Oversight & Governance (US)
$148K - $240K *
Lead the charge in shaping operational risk management strategies, guiding teams, and enhancing internal controls. Collaborate with stakeholders to ensure compliance and drive initiatives that mitigat...
6 days ago
$150K - $180K *
Shape the future of security by leading our first dedicated security function. You'll build and execute a comprehensive security program, ensuring safe AI adoption while protecting sensitive health da...
6 days ago
Speech Language Pathologist -SLP
$83K *
Empower children and families by providing expert speech-language therapy in a collaborative outpatient pediatric setting. Enjoy a flexible schedule and opportunities for professional growth while mak...
6 days ago
$75K - $120K *
Unlock potential by joining a dynamic sales team focused on architectural markets. Drive business growth, build relationships, and present innovative solutions to design professionals while collaborat...
6 days ago
Digital Marketing Senior Consultant
$95K - $115K *
Lead digital marketing strategies to enhance revenue and engagement on Truist.com. Collaborate with stakeholders to optimize user experiences and drive performance through data-driven insights and inn...
6 days ago
Electrical Power Distribution (EPD) Subject Matter Expert (SME)
$118K - $183K *
Drive excellence in electrical power distribution as a Subject Matter Expert, ensuring reliability and safety in critical facilities. Collaborate with teams to optimize performance, lead technical tra...
Reposted 6 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.