Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,696

Sort By: Relevance

$150K - $180K *

Drive the Enablement function for AI deployments, leading strategy and team development. Collaborate with internal teams, customers, and partners to create scalable learning solutions, ensuring succes...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$79K - $118K *

Optimize patient outcomes by leading interdisciplinary teams, conducting assessments, and implementing evidence-based therapeutic techniques. Engage in community outreach and staff development while e...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Drive the product vision and strategy for integrated hardware and software ecosystems, overseeing complex technology development while leading a team of Product Managers to achieve growth and innovati...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Transportation

$71K - $100K *

Lead the charge in delivering exceptional nursing care in a dynamic acute care unit. Collaborate with interdisciplinary teams to ensure optimal patient outcomes while managing complex cases and promot...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$123K - $180K *

Lead the charge in strategic and operational excellence for a network of physician-partnered endoscopy ambulatory surgery centers, ensuring high-quality care and efficient operations while driving fut...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $118K *

Contribute to exceptional patient care by providing skilled nursing across multiple units, adapting to diverse clinical environments while ensuring safety and quality standards are met. Collaborate wi...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Accelerate transformation by leading product strategy and customer experience. Drive innovation at the intersection of genomics and AI, shaping the future of personalized health while building a high...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$70K - $105K *

Collaborate with cross-functional teams to drive project execution and operational excellence in medical communications. Leverage your project management skills to ensure timely delivery and high-qual...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $150K *

Join a team that's dedicated to delivering financial insights and underwriting support in a dynamic environment. Collaborate with experts to enhance loan structuring and decision-making processes whil...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$215K - $355K *

Champion innovation by leading strategic initiatives in cyber engineering, enhancing security assessment and automation while fostering collaboration across teams to ensure enterprise-wide cybersecuri...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Inspire and elevate design excellence as you lead a talented team, setting and maintaining visual standards, driving innovative campaigns, and partnering cross-functionally to advance Dandy's brand an...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Elevate the marketing strategy for the Smart Buildings Electrical Distribution NEMA business line in Latin America. Lead and coach the marketing team while driving profitable growth and ensuring align...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$112K - $223K *

Shape the future of pharmacovigilance by leading global projects, ensuring compliance, and enhancing operational excellence. Collaborate with diverse teams to drive quality and efficiency while mentor...

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Partner with us to lead complex software implementations, ensuring client success through hands-on technical guidance, effective communication, and cross-functional coordination. Drive delivery excell...

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$70K - $90K *

Empower your team by leading workforce engagement to ensure safety, quality, and performance. Collaborate across departments to meet customer delivery expectations while managing a dynamic operational...

6 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $195K *

Accelerate growth by driving sales and building partnerships in healthcare. Leverage your expertise to meet sales objectives, enhance customer relationships, and support product adoption within your t...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $115K *

Unlock potential by providing vital sales support and presentations, driving customer integration and product utilization, while conducting market research to enhance offerings. Collaborate closely wi...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $230K *

Pioneer innovative oncology solutions by building strong relationships with key stakeholders, driving product adoption, and exceeding performance goals in a dynamic biopharma environment focused on pa...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$272K - $374K *

Empower our sales team to drive revenue growth by leading strategic engagements with Federal Systems Integrators. Utilize your expertise to craft account plans, build relationships, and navigate compl...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $120K *

Grow your career with a dynamic sales role, driving supply chain transparency for leading brands. Own the full sales cycle, engage senior stakeholders, and develop solutions that enhance customer valu...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$108K - $250K *

Join a team that's dedicated to enhancing patient care by promoting innovative oncology solutions. You'll engage with healthcare professionals, drive product awareness, and leverage insights to streng...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a dynamic team to provide expert pharmacy services, educate patients, and ensure medication safety. Collaborate with healthcare professionals while advancing your career in a supportive environme...

6 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Join a team that's dedicated to providing expert pharmacy services and patient care. You'll play a vital role in medication management, patient education, and mentoring staff while enjoying growth opp...

6 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$90K - $115K *

Lead field operations for commercial mechanical projects, ensuring safety, quality, and timely execution. Collaborate with teams to deliver high standards while mentoring staff and fostering a strong...

6 days ago

  •   Less than 5 years exp.  •   Technical Services

$103K - $141K *

Take ownership of customer success by driving adoption and value realization of the platform. Leverage your technical expertise to guide clients through onboarding and operationalization, ensuring sat...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.