Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,696

Sort By: Relevance

$87K - $97K *

Oversee and inspire a dedicated outpatient therapy team, delivering exceptional patient care while managing clinic operations and fostering community partnerships to enhance patient outcomes and team...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Support patient recovery by evaluating and treating individuals in an outpatient setting. Collaborate with a dedicated team to enhance patient experiences and outcomes while maintaining compliance wit...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing patient care through expert evaluation and treatment. Collaborate with colleagues and healthcare professionals in a supportive environment focused on complian...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $140K *

Lead a dynamic team to design and develop innovative front-end solutions using React and TypeScript. Mentor engineers, drive technical direction, and ensure high-quality software delivery in a collabo...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Champion preconstruction excellence by leading diverse design-build projects, ensuring effective planning, cost management, and risk assessment. Collaborate with stakeholders to drive successful proje...

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$85K - $100K *

Join a dynamic team to lead water/wastewater design projects, managing scope and budget while leveraging client relationships. Engage in innovative solutions for municipal and private clients, enhanci...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Lead the charge in managing complex water/wastewater projects, leveraging client relationships and technical expertise to deliver innovative solutions while mentoring junior engineers and driving busi...

6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$85K - $100K *

Drive innovative water/wastewater design projects, managing multi-disciplined teams to deliver effective solutions for municipal and industrial clients while ensuring project scope, budget, and timeli...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$210K - $230K *

Lead the charge in driving growth and performance across multiple channels, optimizing customer journeys and aligning cross-functional teams to achieve measurable outcomes in MRR and product expansion...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$169K - $282K *

Join a team that's redefining oncology clinical operations by leading a dynamic portfolio of studies. Drive excellence in delivery, manage complex projects, and mentor a talented team to ensure high-q...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Elevate security posture by leading enterprise asset hardening initiatives, ensuring compliance with security standards and best practices. Collaborate with cross-functional teams to drive remediation...

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate your career by leading enterprise asset hardening initiatives to enhance security posture. Collaborate with cross-functional teams to ensure compliance, drive remediation efforts, and implemen...

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$224K - $431K *

Advance security research at a high bar, validating vulnerabilities and creating reliable fixes while shaping rigorous engineering standards for critical AI Safety & Security initiatives...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in shaping brand experiences across diverse touchpoints, from digital to in-person activations. Own projects from concept to delivery while fostering collaboration and innovation withi...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$111K - $212K *

Empower innovation by leading product strategy and development for complex, cross-functional initiatives. Drive customer-focused solutions through collaboration, research, and experimentation, while m...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$79K - $117K *

Join a team that's driving sales success in the North-East market by cultivating strong partnerships with distributors and end-users, leveraging value selling techniques to exceed goals and enhance cu...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Lead the charge in crafting immersive environments that elevate gameplay and storytelling. Collaborate with teams to create high-quality, modular assets that meet artistic and technical standards, sha...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$120K - $145K *

Elevate your career by leading the architecture and design of Oracle Cloud CX solutions. Collaborate with teams to translate business needs into scalable customer service portals while ensuring alignm...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Staffing

$54K - $159K *

Drive compliance strategy and risk management for Medicaid providers, leading cross-functional initiatives to enhance regulatory performance and operational excellence while fostering partnerships wit...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Drive impactful data science initiatives that enhance business value across multiple domains. Lead a high-performing team to deliver advanced analytics solutions, ensuring alignment with strategic goa...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$180K - $215K *

Drive regional sales success by leading launch execution, building high-performing teams, and fostering customer relationships. Collaborate cross-functionally to achieve strategic goals in a fast-pace...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Transform the commercialization landscape by driving strategic plans that enhance product launches and profitability. Collaborate across functions to ensure successful execution and market performance...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$144K - $288K *

Empower product innovation by leading analytics development, defining strategies, and collaborating with cross-functional teams to enhance patient care and drive impactful solutions in a dynamic envir...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$123K - $164K *

Drive end-to-end design execution for major data center projects, leading multidisciplinary teams to ensure alignment with safety, sustainability, and commercial goals throughout the project lifecycle...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$180K - $215K *

Drive regional sales success by leading a high-performing team, executing launch strategies, and fostering customer relationships to achieve business objectives in a dynamic environment...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.