Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,788

Sort By: Relevance

$135K - $216K *

Lead the charge in integrating DOD MP-ICAM solutions, focusing on CAC/PIV, SAML, and Active Directory. Collaborate with cybersecurity teams to enhance identity controls and support privileged-access w...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$80K - $128K *

Take ownership of deployment workstreams, ensuring alignment of scope, schedule, and quality. Lead execution, manage risks, and coordinate with stakeholders to deliver successful outcomes under the AF...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$112K - $179K *

Architect the migration of legacy health data into MHS GENESIS, leading a team to ensure seamless integration and data quality. Collaborate with stakeholders to define architecture and standards, driv...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Aerospace & Defense

$135K - $155K *

Drive impactful data solutions by bridging business needs with engineering teams. Own project intake, prioritize requests, and ensure clear communication across departments to enhance efficiency and d...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$190K - $200K *

Manage strategic customer engagement and growth within Navy and DoD sectors. Leverage existing networks and industry insights to identify business opportunities that align with Millennium’s objectives...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Information Technology

$115K - $120K *

Elevate software quality by managing test planning, execution, and reporting. Collaborate with development teams, mentor junior testers, and ensure compliance with cybersecurity standards while drivin...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$110K - $135K *

Join a dynamic team to oversee tax engagements, manage client relationships, and mentor junior staff. Utilize your expertise in tax planning and compliance while contributing to various consulting pro...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$175K - $200K *

Transform global talent acquisition by leading a multi-country team, setting strategic vision, and optimizing recruitment processes to meet business growth while ensuring compliance and enhancing cand...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Staffing

$83K - $126K *

Drive seamless client implementations by leading project planning, communication, and execution. Collaborate with internal teams to ensure successful onboarding and enhance client experiences through...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$125K - $133K *

Champion the development of Generative AI solutions, leading an agile team to enhance products and tooling. Drive AI adoption, mentor engineers, and ensure best practices while collaborating across de...

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Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$108K - $115K *

Unlock your potential as a full stack engineer, collaborating in an agile team to develop innovative applications and features, while leveraging cutting-edge AI technologies to enhance product offerin...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Transform your career by guiding strategic growth through identifying and capturing high-value opportunities in the Federal market. Leverage relationships and insights to execute comprehensive capture...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Technical Services

$95K - $115K *

Manage complex environmental and commercial casualty claims, guiding them from inception to resolution. Leverage expertise to analyze coverage, negotiate settlements, and mentor staff while collaborat...

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $180K *

Drive the modernization of Veterans Benefits Administration claims processing by designing and optimizing scalable data pipelines and solutions, ensuring efficient data integration and analytics for i...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$102K - $174K *

Engage with us to lead Agile delivery across multiple Scrum teams, enhancing collaboration and efficiency. Drive continuous improvement, facilitate key ceremonies, and ensure alignment with project go...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$102K - $174K *

Join a team that's redefining user experiences in Robotics and Autonomous Systems. As a UI/UX Designer, you'll create intuitive interfaces, conduct user research, and collaborate with developers to de...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$79K - $110K *

Transform lives by providing compassionate speech therapy to seniors. Collaborate with a dedicated team to evaluate, treat, and develop personalized care plans, ensuring each patient receives the atte...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$87K - $116K *

Unlock potential by providing individualized rehabilitative care to senior patients. Collaborate with a dedicated team to develop and implement tailored treatment plans, ensuring each patient receives...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$230K - $260K *

Oversee regional sales strategies and lead a team to drive oncology product sales. Collaborate cross-functionally to enhance market insights and ensure compliance while fostering team development and...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $210K *

Unlock potential by fostering relationships within the oncology community, executing strategic business plans, and ensuring patient access to therapies while collaborating across functions to drive sa...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$230K - $260K *

Join us to lead a regional sales team, driving strategic initiatives and fostering relationships to achieve business objectives while enhancing patient outcomes in the oncology sector...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $210K *

Develop and execute strategic business plans to enhance patient access and drive sales in the oncology sector, while fostering relationships with key stakeholders and ensuring compliance with industry...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$104K *

Transform lives by providing expert physical therapy to enhance mobility, strength, and independence in a supportive senior living environment, collaborating with healthcare teams to ensure optimal pa...

Today

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Drive global strategic account growth by leading diverse teams, enhancing customer relationships, and executing innovative strategies to maximize retention and revenue across multinational portfolios...

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  •   11 - 15 years exp.  •   Enterprise Technology

$95K - $115K *

Unlock potential by serving as a trusted HR partner, delivering expert guidance and enhancing employee lifecycle experiences. Collaborate with leaders to drive performance and process improvements whi...

United StatesRemote

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  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.