Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,632

Sort By: Relevance

$95K - $115K *

Join our team to enhance clinical systems for medication management, focusing on optimizing workflows and supporting pharmacy operations. Collaborate with stakeholders to ensure accuracy and efficienc...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$136K - $187K *

Champion quality assurance by leading microbiology testing teams, ensuring compliance with GMP and GLP standards. Drive continuous improvement initiatives while collaborating cross-functionally to enh...

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$168K - $231K *

Unlock potential by leading the design and development of innovative software solutions for medical devices. Collaborate with cross-functional teams to ensure high-quality, secure software that enhanc...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$68K - $93K *

Conduct microbiological analyses and support environmental monitoring programs. Collaborate with cross-functional teams to ensure compliance with regulatory standards and maintain data integrity in a...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $189K *

Support Department of Defense operations by configuring SAP S/4HANA for finance and logistics. Collaborate with stakeholders to enhance enterprise systems, ensuring seamless integration and compliance...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$63K - $129K *

Shape your career by driving Agile execution excellence in federal HCM modernization. Lead cross-functional teams, facilitate SAFe ceremonies, and foster a continuous improvement culture within a larg...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Information Technology

$114K - $252K *

Unlock potential by leading software development initiatives, ensuring system integration, and guiding teams through agile methodologies to deliver high-quality solutions that meet customer requiremen...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Information Technology

$131K - $224K *

Shape the future of consumer payments by leading strategic initiatives, analyzing market trends, and collaborating with cross-functional teams to drive growth and innovation in the payments landscape...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Join a team that's driving supplier engagement through consultative sales. Leverage your financial acumen to onboard suppliers for a high-growth working capital solution, collaborating with C-level ex...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $163K *

Optimize application security by designing, implementing, and automating scalable processes, leading technical integrations, and enhancing risk mitigation strategies across diverse environments and te...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $196K *

Explore complex financing solutions as a Senior Secured Lending Underwriter, managing diverse vendor and dealer relationships. Evaluate creditworthiness, structure financing, and influence key decisio...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $179K *

Elevate client experiences by leading a team in Treasury Management implementations, focusing on healthcare and not-for-profit sectors. Drive operational excellence and foster team development while n...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$139K - $260K *

Join a dynamic team as you provide legal support for Merchant Services, guiding product development and compliance while addressing complex regulatory issues and risk management strategies to enhance...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Elevate analytical capabilities by re-engineering Treasury models and workflows. Leverage cross-functional expertise in balance sheet management and AI to drive modernization and deliver robust, reusa...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Elevate your career by leading enterprise data risk management initiatives. Collaborate across teams to assess and enhance data governance, metadata management, and lineage tools, ensuring robust over...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$115K *

Unlock potential as you analyze complex financial models and market trends, assess risks, and prepare detailed financial reviews to support strategic decision-making in commercial real estate investme...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$87K - $140K *

Champion strategic initiatives across multiple business groups, ensuring operational efficiency and quality. Lead support functions, collaborate with teams, and drive impactful programs in a dynamic e...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Lead and execute regulatory strategies for multi-region clinical trials, ensuring compliance and timely submissions. Collaborate with project teams to manage risks and drive operational excellence thr...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$118K - $180K *

Join a dynamic team enhancing nuclear power plants through advanced engineering. Leverage your expertise in thermodynamics and fluid mechanics to drive power uprate projects, mentor junior staff, and...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Technical Services

$100K - $152K *

Empower progress in environmental compliance by developing air permitting strategies for complex industrial projects. Collaborate with multi-disciplined teams to ensure adherence to air quality regula...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Technical Services

$145K - $222K *

Lead a structural engineering team, guiding projects for nuclear facilities. Utilize your expertise in design and analysis while collaborating with clients and multidisciplinary teams to deliver innov...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Technical Services

$132K - $174K *

Shape the future of environmental consulting by leading complex projects, fostering client relationships, and driving strategic initiatives. Collaborate with multidisciplinary teams to ensure excellen...

RemoteRemote

4 days ago

  •   11 - 15 years exp.  •   Energy & Utilities

$110K - $130K *

Elevate product execution by translating client needs into actionable requirements, collaborating with engineering and data science teams to deliver standardized measurement solutions across various c...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$89K - $113K *

Transform data integrity by assisting in the analysis and cleansing of Enterprise Business Systems. Collaborate with teams to resolve anomalies and ensure compliance with DoD standards while supportin...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $120K *

Manage hospital facilities operations, ensuring compliance and safety standards while overseeing maintenance, engineering, and emergency response initiatives. Collaborate with leadership to enhance op...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.