Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,632
$100K - $120K *
Join a dynamic team as you provide exceptional pharmaceutical services, ensuring customer satisfaction while adhering to safety standards. This role offers growth opportunities and valuable leadership...
Reposted 3 days ago
$100K - $120K *
Elevate patient care by applying your pharmacy expertise while providing outstanding service. Collaborate with healthcare professionals to enhance pharmacy operations and build lasting relationships w...
Reposted 3 days ago
Senior Auditor, BRC Food Safety
$90K - $110K *
Lead third-party food safety audits, ensuring compliance with industry standards. Collaborate with audit teams, train new auditors, and maintain certification credentials while traveling extensively a...
3 days ago
Core AE Southeast [FY27][Pipeline]
$222K - $278K *
Lead the charge in transforming enterprise operations by consolidating technologies and digitizing workflows. Engage with strategic customers to unlock insights that enhance efficiency and sustainabil...
3 days ago
$80K - $95K *
Drive the future of life sciences by supporting financial and scientific diligence for investments, monitoring tenant performance, and engaging with the ecosystem to identify opportunities and risks a...
3 days ago
Senior Manager, Release Engineering & Site Reliability (DevOps , CI/CD)
$196K - $292K *
Elevate the quality of software qualifications by leading a high-performing CI/CD engineering team. Drive automation and operational excellence, ensuring readiness for partner environments while colla...
Reposted 3 days ago
Marketplace Channels Lead | Marketplace Center of Excellence (CoE)
$129K - $192K *
Lead the charge in optimizing marketplace strategies and partnerships, driving revenue growth through collaboration with hyperscalers and channel partners. Utilize your expertise to enhance operationa...
3 days ago
$170K - $253K *
Unlock potential by designing and developing innovative storage solutions in a dynamic team environment. Contribute to advanced features of a robust storage platform serving critical applications acro...
Reposted 3 days ago
Sr. Technical Marketing Engineer
$196K - $292K *
Advance your career by leading technical strategies for hybrid cloud and AI infrastructure solutions, connecting capabilities to customer value, and driving innovative initiatives that influence produ...
Reposted 3 days ago
$200K - $230K *
Champion client relationships and operational excellence while overseeing a large Life Sciences portfolio. Lead a diverse team, manage P&L, and drive strategic initiatives to ensure client satisfactio...
3 days ago
$95K - $115K *
Manage nationwide aviation operations, ensuring compliance with safety regulations and effective training programs. Develop guidelines for wildlife aviation and provide strategic leadership across var...
3 days ago
HR Director - Electrical Engineering Services & Systems
$165K - $266K *
Drive strategic HR leadership for a high-growth division, aligning talent strategies with business objectives to enhance performance and foster an inclusive culture. Partner with leadership to build w...
3 days ago
$95K - $115K *
Unlock potential by leading plant technical functions, driving operational excellence, and ensuring the reliable operation of production systems. Manage maintenance and engineering teams to enhance sa...
Reposted 3 days ago
Application Engineer - Seattle, WA
$95K - $120K *
Unlock potential by serving as a technical partner to sales, providing expertise in automation solutions. Manage application opportunities, engage with customers, and recommend improvements to align t...
3 days ago
$81K - $126K *
Lead the charge in transforming urban landscapes by overseeing major projects, managing budgets, and collaborating with diverse stakeholders to implement innovative designs and improvements at a promi...
3 days ago
Sr. Strategic Insights Manager
$130K - $160K *
Join a team that's dedicated to delivering data-driven solutions for life sciences clients. Leverage your expertise to drive insights, optimize user experiences, and collaborate with cross-functional...
3 days ago
HR Director - Electrical Engineering Services & Systems
$165K - $266K *
Transform organizational effectiveness by leading HR strategies that align talent with business goals, fostering a high-performance culture, and driving workforce planning for sustainable growth in a...
3 days ago
$108K - $130K *
Partner with us to ensure compliance and enhance quality by leading investigation teams, managing CAPA processes, and driving operational excellence across pharmaceutical manufacturing in a high-paced...
Reposted 3 days ago
$120K - $192K *
Join a team that's shaping innovative web solutions as a Development Lead. Drive full-stack delivery while mentoring engineers in a dynamic Agile environment, fostering a culture of ownership and cont...
Reposted 3 days ago
$80K - $95K *
Lead the charge in ensuring compliance of incoming materials with quality standards. Oversee inspections, drive supplier collaboration, and mentor a dedicated team in a cGMP-regulated environment, str...
Reposted 3 days ago
Lead Mgr - Pricing Capabilites & Infrastructure
$95K - $115K *
Shape the future of pricing capabilities by collaborating with cross-functional teams to design, implement, and support processes and tools that enhance business operations and drive effective user ad...
Reposted 3 days ago
$88K - $105K *
Empower your career by providing technical leadership in microbiological quality for aseptic pharmaceutical manufacturing. Oversee vital processes, ensure compliance with regulatory standards, and sup...
Reposted 3 days ago
PROJECT MANAGER (HEAVY CIVIL CONSTRUCTION)
$88K - $105K *
Take ownership of project management for large-scale construction initiatives. Collaborate with teams to ensure timely delivery, financial health, and quality outcomes, while fostering strong relation...
Reposted 3 days ago
Senior EWM Techno-Functional Consultant
$110K - $130K *
Transform warehouse operations by leveraging your SAP EWM expertise. In this role, you’ll optimize solutions, deliver hands-on support, and collaborate with cross-functional teams to elevate logistics...
Reposted 3 days ago
$109K - $160K *
Transform your career by managing web production and enhancing user experiences. Collaborate with cross-functional teams to prioritize projects, execute testing roadmaps, and optimize web performance...
3 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.