Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,632

Sort By: Relevance

$222K - $288K *

Advance your career by leading global infrastructure strategy and operations. Drive modernization across cloud, networking, and security while ensuring compliance and scalability for 24/7 clinical and...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Healthcare

$88K - $105K *

Transform critical semiconductor processes by leading multi-functional teams, enhancing tool utilization, and driving new product rollouts in a dynamic, fast-paced environment. Collaborate with engine...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$72K - $112K *

Serve as a vital link in healthcare by providing expert technical support for imaging equipment. You'll ensure optimal performance through installation, troubleshooting, and maintenance, while fosteri...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$72K - $112K *

Optimize customer relationships by providing expert technical support for installation, troubleshooting, and maintenance of imaging equipment. Collaborate with teams to enhance service delivery and en...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Advance your career by managing clinical monitoring and site management processes. Ensure compliance with protocols and regulations while fostering relationships with investigational sites. Contribute...

North Carolina, USRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead high-profile statistical projects, ensuring rigorous evidence generation by collaborating with multi-functional teams to design studies and analyze data effectively...

North Carolina, USRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the charge in fostering a positive workplace culture by conducting thorough investigations into employee relations issues, ensuring fairness and integrity throughout the process while collaborati...

North Carolina, USRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform partner relationships by driving co-selling, co-marketing, and enablement initiatives. Collaborate with internal teams and partners to enhance client satisfaction and ensure successful proje...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$75K - $100K *

Lead the charge in emergency restoration services by managing a dedicated team. Oversee fire and water damage projects, ensuring effective communication with clients and vendors while promoting busine...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Join a team that's driving consumer banking growth by leading a dynamic group of Workplace Banking Relationship Bankers. You'll establish sales strategies, foster partnerships, and cultivate a high-pe...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$82K - $123K *

Champion AI innovation by driving tool adoption, engineering practices, and workforce enablement across the enterprise. Collaborate with cross-functional teams, influencing leaders and building future...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$71K - $119K *

Drive customer success by leveraging expertise in intellectual property solutions, enhancing product adoption, and delivering exceptional experiences through strategic engagement and training initiati...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Shape the future of enterprise support by managing Red Hat Linux systems, optimizing performance, and ensuring compliance with security protocols. Collaborate with a dynamic team to enhance system adm...

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$92K - $110K *

Take ownership of delivering exceptional patient care by providing primary health services under physician guidance. Collaborate in a supportive environment that values teamwork, diversity, and safety...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to providing exceptional pharmaceutical care, overseeing medication therapy, and ensuring compliance with regulations while collaborating with healthcare professionals to...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Empower your career by joining a dedicated team focused on delivering exceptional patient care in behavioral health and addiction treatment. Contribute to recovery journeys through comprehensive asses...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $115K *

Shape and execute category strategy implementation across multiple Distribution Centers, ensuring alignment with national goals while addressing local market needs and driving profitable sales growth...

3 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$105K - $124K *

Lead the charge in executing the Issue Management program, collaborating with stakeholders across Investment Services to ensure effective resolution of issues, validate corrective actions, and maintai...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$113K - $188K *

Contribute to innovative Salesforce solutions by leveraging your development expertise. Collaborate with cross-functional teams to design, build, and maintain scalable applications, ensuring high perf...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$74K - $124K *

Drive innovation by enhancing Power Platform tools for executive-level operations. Manage full lifecycle processes, ensuring compliance and improving operational efficiency through workflow automation...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Business Services

$175K - $291K *

Shape the future of AI by leading enterprise-level initiatives across multiple business units, driving investment decisions, and mentoring teams to achieve transformative results with cutting-edge tec...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by driving sales in the supply chain and food & beverage sector. Foster strong client relationships, develop tailored marketing strategies, and exceed quotas through innovative busine...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$151K - $237K *

Transform healthcare outcomes by engaging with KOLs and HCPs, analyzing scientific data, and fostering expert networks. Drive medical strategy and enhance patient care through compliant, insightful co...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $93K *

Manage and supervise operations staff to ensure safe, reliable, and efficient functioning of complex steam and electric generating facilities. Provide technical leadership and coordinate operational s...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$78K - $102K *

Drive exceptional customer experiences by leading a high-impact team, overseeing sales and delivery operations, and ensuring performance goals are met. Collaborate cross-functionally to enhance commun...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.