Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,632

Sort By: Relevance

$85K - $90K *

Join a dynamic team as a strategic leader in enrollment communications, overseeing marketing initiatives that enhance recruitment and student engagement. Collaborate with key stakeholders to drive eff...

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Transform aircraft systems and maintenance programs to ensure safe, compliant, and reliable operations for the CRJ-700/900 platform, collaborating across teams to enhance safety and performance for cr...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$120K - $160K *

Join a team to lead commissioning projects, providing technical expertise and project management for critical facilities. Collaborate across teams, mentor others, and ensure successful testing and val...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Technical Services

$385K - $400K *

Transform regional sales performance by leading a high-impact team, driving strategic growth, and utilizing best practices to meet ambitious quotas within a dynamic environment. Foster relationships a...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$212K - $287K *

Transform the Hematology landscape by leading a high-performing sales team, driving strategic initiatives, and ensuring compliance while exceeding sales objectives in the Great Plains region...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$102K - $176K *

Drive operational excellence by partnering with leadership to enhance strategic initiatives, optimize resource performance, and implement effective solutions that elevate client experiences and minimi...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$55K - $126K *

Elevate operational excellence by providing critical technical support for advanced simulation systems. Collaborate with elite teams to troubleshoot, maintain, and innovate solutions that enhance trai...

3 days ago

  •   Less than 5 years exp.  •   Business Services

$184K - $356K *

Drive technical engagement with telecom accounts, connecting customer workloads to NVIDIA's ecosystem. Serve as a trusted advisor, co-design scalable architectures, and lead technical enablement to en...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$145K - $170K *

Join us to drive strategic sales initiatives, leveraging a robust resource model and tech stack to achieve performance goals and maximize customer value in a dynamic, collaborative environment...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$72K - $102K *

Deliver exceptional patient care by assessing and developing individualized perianesthesia plans, ensuring accurate communication during hand-offs, and performing essential nursing duties in a fast-pa...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Transform the claims landscape by managing commercial property claims, collaborating with diverse teams, and enhancing your expertise in global and excess lines. Join a dynamic environment focused on...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $200K *

Transform healthcare delivery by providing comprehensive care to geriatric patients. Collaborate with a multidisciplinary team to enhance the quality of life for seniors in community settings, ensurin...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Advance community operations by leading a dedicated team, ensuring compliance, and enhancing resident satisfaction. Drive financial performance and foster relationships within the community to promote...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower the CDL program by leading training initiatives, ensuring compliance, and optimizing fleet management. Collaborate with regional leaders to enhance operational efficiency and drive revenue gro...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Lead transformative leadership workshops and mentorship programs, empowering managers to enhance their skills and foster a thriving workplace culture. Collaborate with internal and external partners t...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $95K *

Join a dynamic team to ensure data accuracy and risk management in Commercial Real Estate. Manage post-close loan reviews, collaborate with stakeholders, and drive process improvements while maintaini...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $160K *

Lead the charge in developing and executing CMC strategies for antibody-based radiopharmaceuticals, ensuring alignment with Stage-Gate requirements while managing cross-functional teams and external p...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $135K *

Shape impactful training programs for Field Access teams, enhancing access and reimbursement capabilities across therapeutic areas. Collaborate with stakeholders to ensure compliance and relevance, fo...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$112K - $189K *

Lead the charge in delivering exceptional pharmaceutical care by interpreting prescriptions, consulting with patients, and ensuring quality assurance. Collaborate with healthcare professionals to opti...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower developers by diagnosing and resolving complex technical issues related to APIs. Collaborate across teams, advocate for improvements, and enhance developer experiences in a fast-paced, innovat...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$250K - $500K+*

Empower your career by joining a dynamic team dedicated to exceptional patient care. Collaborate with professionals, enjoy flexible scheduling, and explore partnership opportunities while making a pos...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$195K - $325K *

Join a team that's shaping the future of AI in healthcare by leading multi-year strategies, resolving complex technical challenges, and influencing executive decisions across the organization to ensur...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Join a dynamic team to develop and enhance SaaS applications, utilizing Agile methodologies. Collaborate with peers, support customers, and drive innovative solutions while staying updated on technica...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$132K - $251K *

Join a team that's redefining data governance through innovative integration and automation solutions. Collaborate across functions to design scalable architectures that enhance data management capabi...

North Carolina, USRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$67K - $117K *

Lead a dedicated team to enhance Vocational Rehabilitation services for individuals with disabilities. Oversee program compliance, staff development, and community partnerships to ensure quality servi...

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.