Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$153K - $220K *

Shape the market presence of our innovative cybersecurity solutions through strategic messaging, product launches, and sales enablement. Collaborate with teams to drive demand and elevate the buyer's...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$93K - $140K *

Elevate cloud security by enhancing standards and implementing risk-based controls across Azure and AWS. Collaborate with teams to secure applications and support AI initiatives, ensuring robust gover...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$97K - $161K *

Drive the design and implementation of security systems, enhancing existing solutions while solving complex challenges. Collaborate with cross-functional teams to ensure robust cybersecurity measures...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Grow your career with a dynamic role managing end-to-end event strategies, logistics, and sales partnerships. Drive impactful industry conferences and user events that significantly contribute to pipe...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $125K *

Join a team that's dedicated to delivering expert tax solutions while ensuring compliance and fostering client relationships. Leverage your extensive experience in tax preparation and planning to driv...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$180K - $210K *

Accelerate progress at the forefront of AI integration, designing secure enterprise architectures that enhance healthcare services for Veterans. Lead initiatives across cloud and on-premise platforms...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$158K - $197K *

Transform real-world health data into actionable insights by leveraging advanced bioinformatics and AI techniques. Lead innovative analyses in oncology and genomics, facilitating cross-functional coll...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Shape the future of medical communications by crafting high-quality, scientifically accurate content. Collaborate with diverse teams to deliver impactful resources that meet client needs while mentori...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$157K - $361K *

Drive innovation in AI and on-premises object storage by creating technical content, benchmarks, and solutions. Collaborate with cross-functional teams to optimize infrastructure and enhance customer...

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$124K - $207K *

Transform global benefits strategies by leading a dynamic team, ensuring compliance, and enhancing employee wellbeing. Drive innovative solutions while managing vendor relationships and collaborating...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $165K *

Empower your career by leading a dynamic SALT practice, delivering expert sales tax consulting services, and driving business development while mentoring a talented team in a collaborative environment...

3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$150K - $159K *

Lead the charge in transforming audience intelligence through innovative product strategies, enhancing consumer insights and data-driven solutions for brands and partners while ensuring privacy and co...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $159K *

Drive product health standards by defining metrics and telemetry for all products. Collaborate with cross-functional teams to ensure consistent data definitions and empower teams with self-serve dashb...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Advance payer integrations by managing complex processes and relationships. Drive outreach and research to establish direct connectivity with 3,000+ payers, ensuring accurate data and efficient handof...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$54K - $159K *

Champion contract negotiations by driving initiatives, cultivating relationships, and ensuring compliance with performance goals. Leverage expertise to support cost-saving strategies and enhance cross...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Manage labor and employment legal matters, ensuring compliance and providing strategic counsel. Collaborate with HR and stakeholders to develop solutions, supervise outside counsel, and educate on pol...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Media

$120K - $145K *

Unlock health equity and quality improvement by leading strategic initiatives that enhance outcomes and reduce disparities across diverse populations in value-based care settings. Collaborate with sta...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join us to drive strategic marketing initiatives across regions, aligning divisional goals with corporate standards. Collaborate with teams to enhance customer acquisition and brand recognition while...

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $145K *

Drive mobile engineering excellence by leading app development, mentoring engineers, and integrating AI solutions to enhance user experiences across iOS and Android platforms while collaborating with...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$80K - $95K *

Join a dynamic team as a strategic HR partner, driving organizational success through effective talent management, employee engagement, and operational support. Collaborate with leaders to align HR in...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$100K - $150K *

Accelerate progress at a dynamic SaaS company by driving revenue growth through strategic sales cycles. Leverage your expertise in complex enterprise solutions to build relationships and exceed target...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$99K - $232K *

Grow your career by leading data migration projects in banking. Drive operational efficiency and mentor teams while implementing innovative software solutions to enhance client satisfaction and projec...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$235K - $280K *

Lead the charge in shaping a high-performing engineering team to manage a robust data platform. Drive architectural decisions, optimize costs, and ensure reliability while collaborating closely with s...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$124K - $280K *

Champion seamless integration solutions that enhance data flow and optimize business processes in financial services. Inspire and lead diverse teams, utilizing advanced architecture designs to achieve...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $145K *

Champion the development of enterprise-grade AI solutions, leveraging Google Cloud Platform and advanced AI technologies. Collaborate with cross-functional teams to deliver secure, scalable, and maint...

3 days ago

  •   5 - 7 years exp.  •   Staffing

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.