Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$92K - $166K *

Lead complex, customer-driven projects from initiation to delivery, ensuring accountability for scope, schedule, and resources. Collaborate across functions to drive strategic planning and deliver act...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Join a team that's redefining product management by leading AI and automation initiatives. Drive strategic roadmaps, enhance operational efficiency, and deliver impactful solutions while collaborating...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$182K - $226K *

Unlock potential by joining a dynamic team that drives customer success through technical expertise and innovative solutions, enhancing product engagement and collaboration in a fast-paced startup env...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Shape your career as you engage with diverse teams, manage costs, and enhance client value in an evolving environment. Take ownership of impactful projects while fostering relationships and driving pr...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$135K - $160K *

Drive a unified technical organization to enhance customer support from application discovery to project conversion, focusing on team development, technical selling, and improving customer experiences...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $199K *

Transform the future of life sciences by leading automation projects, mentoring teams, and driving innovation. Collaborate with clients to enhance operational efficiency and ensure compliance while fo...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $199K *

Lead a dynamic team in driving automation solutions within life sciences, enhancing operational efficiency and client engagement. Collaborate across functions to deliver high-quality projects while fo...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $199K *

Lead the charge in enhancing automation solutions within life sciences, driving project success through technical expertise and client collaboration. Foster team growth and innovation while ensuring c...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $172K *

Transform healthcare delivery by managing CDI operations, liaising with vendors, ensuring quality, and fostering staff development. Join a collaborative team to enhance patient care through innovative...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$220K - $288K *

Unlock potential by leading technical discovery and crafting data solutions that drive business outcomes. Collaborate with sales and partners to present innovative data architectures and deliver impac...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $176K *

Engage in transforming patient care by leading a pharmacy team to deliver exceptional service, ensuring compliance, and fostering a culture of excellence while managing operations and mentoring staff...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead the charge in offensive security research, tackling software supply chain vulnerabilities and zero-day threats. Collaborate with teams to innovate security capabilities and publish impactful find...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$173K - $209K *

Transform your career by leading biostatistical strategies for clinical trials, driving innovative therapies from design to regulatory submission. Collaborate with multidisciplinary teams to ensure da...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Join a dynamic team to design and develop innovative mobile solutions across Android and iOS. Take ownership of projects, collaborate with peers, and contribute to the broader tech stack while enhanci...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $95K *

Drive project success by leading archaeological surveys, coordinating teams, and ensuring compliance with federal regulations. Manage schedules, deliverables, and stakeholder communications for high-q...

3 days ago

  •   8 - 10 years exp.  •   Technical Services

$233K - $330K *

Elevate your career by leading innovative pricing strategies for cutting-edge AI solutions. Collaborate across teams to optimize monetization models and drive value in a dynamic market, ensuring Cisco...

RemoteRemote

3 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$90K *

Drive strategic and clinical leadership for outpatient therapy services across multiple clinics, ensuring high-quality patient care, operational consistency, and regulatory compliance while fostering...

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$108K - $130K *

Engage in high-impact enterprise sales by driving new business acquisition and managing C-suite relationships. Leverage cloud expertise to close large recurring revenue deals while executing complex s...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Lead the charge in enterprise sales by driving new business acquisition, managing complex sales cycles, and building strong relationships with C-level executives. Leverage cloud expertise to deliver t...

Raleigh, NCRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in managing complex manufacturing projects, ensuring client satisfaction and project delivery from concept to execution. Collaborate with design teams to translate production intent in...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$220K - $275K *

Accelerate growth by leading the demand engine for the Integrated Solutions SBU, driving bookings and revenue across Space and Aerospace & Defense markets while ensuring alignment with strategic goals...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$105K - $150K *

Lead product management for complex digital services, mentoring a team of Product Managers. Collaborate with stakeholders to define strategies, prioritize needs, and deliver impactful outcomes while f...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$143K - $185K *

Champion innovative solutions by leading technical sourcing for memory and storage. Collaborate with engineering and suppliers to ensure manufacturability and performance, driving projects from concep...

3 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$150K - $200K *

Lead the charge in delivering complex federal digital services programs, ensuring strategic direction, operational excellence, and strong customer relationships across multidisciplinary teams while ma...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $140K *

Innovate cloud solutions by designing and automating infrastructure in Cloud.gov and Azure. Collaborate with teams to enhance performance and security, driving impactful results for clients while shap...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.