Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$100K - $120K *

Join a team that's dedicated to improving patient outcomes through innovative ambulatory care! Collaborate with healthcare providers and develop individualized treatment plans while engaging in resear...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$98K - $125K *

Accelerate your career by enhancing technical sales skills through impactful training programs. Engage with diverse technologies and lead learning experiences that drive success in networking, securit...

3 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$98K - $125K *

Elevate progress at Cisco by designing and delivering impactful training programs that enhance the skills of technical sales professionals, driving success across diverse technology domains and foster...

North Carolina, USRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$75K - $90K *

Transform client objectives into impactful paid social strategies. Oversee campaign execution, optimize performance, and mentor junior team members while driving cross-functional collaboration to achi...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Lead all HR functions in a dynamic biotech environment, enhancing employee experience and compliance while driving scalable processes and supporting leadership. Engage with teams to foster growth and...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$72K - $90K *

Optimize customer journeys by owning lifecycle initiatives, translating strategy into actionable requirements, and driving performance improvements. Collaborate with cross-functional teams to enhance...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Unlock growth by leading RevOps initiatives that enhance acquisition, strengthen pipelines, and optimize seller performance through data-driven strategies and robust analytics, ensuring alignment with...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$89K - $165K *

Transform your career by applying advanced engineering techniques to tackle complex design and analysis tasks. Collaborate with multi-functional teams to enhance product development and ensure high-qu...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Contribute to the development of our sales team by implementing systems for skill enhancement, performance tracking, and strategic field execution, aiming for excellence in agency collaborations and m...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$141K - $216K *

Drive operational excellence as a key account manager, collaborating with a Senior AE to enhance customer satisfaction and business execution in the AI infrastructure and Scale Cloud sectors. Embrace...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Empower innovation by leading research in AI computing infrastructure. Collaborate with a talented team to translate cutting-edge systems research into impactful products, balancing long-term vision w...

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Accelerate progress at clinical sites by enhancing patient recruitment strategies and supporting Oncology studies. Collaborate with teams to optimize enrollment processes and ensure effective communic...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$228K - $285K *

Transform the design landscape by leading a talented team to elevate visual and interaction quality in financial software. Drive innovation, simplify complex workflows, and inspire designers to delive...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$84K - $126K *

Shape the future of logistics operations by leading teams, driving improvements, and ensuring compliance with quality and safety standards while managing resources effectively to meet business goals...

3 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$93K - $117K *

Join a team that's shaping data-driven decisions by building robust analytics models, collaborating with stakeholders, and ensuring data integrity. Leverage your expertise in SQL and BI tools to empow...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$190K - $200K *

Lead the charge in executing capital markets strategies for debt financings, managing end-to-end deal processes, and collaborating across teams to ensure compliance and reporting for a growing portfol...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$132K - $302K *

Lead the charge in driving AWS-focused business development initiatives, enhancing market strategies, and fostering partnerships to accelerate cloud adoption and sales growth across enterprise account...

3 days ago

  •   8 - 10 years exp.  •   Business Services

$132K - $302K *

Unlock potential by driving AWS-focused business development strategies, fostering partnerships, and executing go-to-market initiatives to enhance cloud adoption and market share within the financial...

3 days ago

  •   8 - 10 years exp.  •   Business Services

$78K - $103K *

Champion accurate coding by interpreting diagnoses and resolving claim errors in this remote role. Leverage your expertise to ensure compliance with CPT, ICD-10, and HCPCS standards while collaboratin...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Champion external sourcing strategies and cost governance, driving collaboration across teams to enhance sourcing execution, maintain cost integrity, and ensure compliance. Lead initiatives that foste...

3 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$87K - $235K *

Unlock potential by leading diverse engagements across industries, driving business improvement and strategic sourcing. Collaborate with teams to deliver results while fostering individual growth and...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$87K - $235K *

Shape impactful business strategies by leading diverse teams in optimizing performance across various industries. Drive engagement delivery and foster collaboration while ensuring tangible results thr...

3 days ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Drive the resolution of complex surety disputes by conducting technical analyses, collaborating with consultants, and advising on construction and claims management, while leading teams to assess risk...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $115K *

Empower patients on their transplant journey by coordinating comprehensive care, collaborating with multidisciplinary teams, and ensuring optimal outcomes for post-liver transplant recipients. Your ex...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$103K - $181K *

Unlock your potential by leading innovative rail transit projects, managing complex CBTC systems, and ensuring compliance with industry standards while fostering a culture of continuous improvement an...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.