Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$120K - $145K *

Inspire a high-performing engineering team by driving strategy, operational excellence, and collaboration across multiple locations. Lead initiatives that foster innovation and professional growth whi...

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$175K - $210K *

Lead pioneering evidence generation initiatives to inform oncology product strategies and lifecycle management through cross-functional collaboration and data-driven decision-making...

RemoteRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $138K *

Champion comprehensive urologic care by collaborating with a dynamic team of surgeons and APPs. Focus on inpatient and outpatient management, performing procedures, and enhancing patient outcomes in a...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Optimize enterprise observability and application performance monitoring by leading a team of engineers. Drive Dynatrace platform strategy, establish monitoring standards, and enhance full-stack visib...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$99K - $148K *

Elevate patient care by providing neurology services in a collaborative outpatient setting. Enjoy a flexible schedule with no weekends or call, while managing follow-up care for stroke and routine pat...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$177K - $265K *

Join a team that's dedicated to safeguarding player experiences by investigating and combating cheating in games. Leverage your analytical skills to create data-driven reports and collaborate with eng...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$150K - $180K *

Lead and grow a high-performing platform engineering team, setting vision and roadmap while collaborating with cross-functional leaders to enhance product velocity and reliability for enterprise custo...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in client strategy and Meta campaign management, ensuring optimal performance and strong relationships. Own a portfolio of accounts, drive results, and proactively solve issues to enha...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$146K - $206K *

Join a dynamic team to build secure customer authentication features, enhancing user experiences across B2C and B2B platforms. Collaborate with engineers to develop backend services and APIs, ensuring...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Take ownership of client relationships and campaign performance, managing a portfolio of accounts. Lead strategy discussions, optimize Meta campaigns, and ensure client satisfaction through proactive...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Deliver excellence in quality management by leading initiatives that ensure compliance with ISO standards, enhance production processes, and foster a culture of continuous improvement within the organ...

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$138K - $165K *

Join a dynamic team as a Principal IT Software Developer, leading AI-driven cloud automation initiatives. Drive technical strategy, enhance workflows, and mentor engineers while ensuring secure, scala...

3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$156K - $212K *

Shape the future of training by leading impactful learning solutions for obesity and related conditions. Collaborate with cross-functional teams to design and deliver engaging curricula that enhance f...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$65K - $121K *

Optimize inventory management to ensure mission readiness throughout system life cycles. Collaborate with suppliers and military operations to manage assets, resolve issues, and support logistics cont...

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$125K - $150K *

Innovate AI solutions by developing tools and integrations that enhance workflows, drive efficiency, and empower teams. Collaborate across departments to implement scalable AI applications that delive...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$101K - $135K *

Champion project management excellence across K-12, Life Sciences, and Commercial sectors, ensuring client advocacy and team collaboration while leading local and national projects to successful compl...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$94K - $143K *

Lead the charge in developing structural designs using advanced modeling software. Collaborate with multi-disciplinary teams to create detailed drawings and resolve design challenges, ensuring timely...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

$162K - $200K *

Unlock your potential by serving as a key legal partner, guiding commercial transactions and enhancing our legal infrastructure while collaborating cross-functionally to drive efficiency and complianc...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$138K - $165K *

Lead strategic pricing initiatives by connecting data to insights, optimizing processes, and enhancing competitive intelligence. Collaborate with senior leadership to drive impactful pricing decisions...

3 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$190K - $285K *

Shape the future of database protection by owning the Oracle roadmap, collaborating with engineering teams, and driving cross-database initiatives to enhance recovery solutions for critical enterprise...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Transform enterprise sales strategies by identifying and addressing client needs in Logistics and Manufacturing. Drive national account growth through innovative solutions, relationship building, and...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Staffing

$87K - $108K *

Join a team that's shaping the future of water and energy utilities by leading proposal development, coordinating resources, and implementing winning strategies. Collaborate with experts to create imp...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$63K - $156K *

Lead strategic account-based selling to healthcare providers, driving adoption of our portfolio. Build relationships, utilize data insights, and navigate the healthcare landscape to enhance customer e...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $165K *

Elevate your career by independently underwriting complex surety submissions, fostering agent relationships, and driving business growth while mentoring junior underwriters in a dynamic remote environ...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Elevate patient care by joining a dedicated team focused on evidence-based orthopedic therapy. Collaborate with physicians to enhance patient outcomes in a supportive environment, ensuring a remarkabl...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.