Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$201K - $251K *

Champion Quality governance by leading the development and management of Quality Agreements across global operations, ensuring compliance and effective partnerships with internal and external stakehol...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Partner with us to drive sales success in a luxury medical practice, utilizing consultative techniques to enhance client relationships and ensure exceptional patient experiences while collaborating wi...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $120K *

Join a team that's dedicated to selling exceptional vacation packages, fostering relationships, and exceeding sales targets. Enjoy comprehensive training and a collaborative environment while unlockin...

3 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$117K - $146K *

Lead the charge in developing innovative algorithms and pipelines for early cancer detection, collaborating with cross-functional teams to analyze complex genomic datasets and enhance clinical diagnos...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$62K - $125K *

Transform the sales landscape by building your own pipeline through relentless prospecting and effective demos. Collaborate with leadership to refine strategies and drive growth in a dynamic startup e...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$132K - $220K *

Transform project delivery by leading planning and scheduling initiatives across diverse teams, ensuring alignment with strategic goals and compliance standards while fostering project excellence and...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Business Services

$132K - $220K *

Lead project planning and scheduling initiatives across the Canada region, ensuring alignment with business objectives and contractual milestones while optimizing project performance and mentoring tea...

Wilmington, NCRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$70K - $118K *

Join a dynamic team to deliver impactful data analysis and reporting solutions, enhancing operational efficiency and decision-making through the Microsoft Power Platform and hands-on analytical suppor...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Empower your career by cultivating client relationships and driving sales growth. This role focuses on renewing software subscriptions and upselling products, leveraging strategic insights to enhance...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $160K *

Partner with us to showcase cutting-edge workforce management solutions, leveraging your pre-sales expertise and presentation skills to drive value for prospective clients in a dynamic, fast-paced env...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's redefining lighting design by leading innovative projects from concept to completion. Collaborate with architects and clients to create sustainable, human-centric environments acros...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$46K - $122K *

Join a team that's redefining healthcare contracts by leveraging financial expertise and strategic negotiation skills to enhance client relationships and drive business success in a dynamic environmen...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead cross-functional projects in health plan relations, enhancing revenue cycle performance and outcomes. Utilize strong communication and project management skills to coordinate initiatives, track p...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$54K - $155K *

Lead the charge in telephonic case management, collaborating with patients and care teams to support quality healthcare delivery. Use clinical expertise to assess needs, implement strategies, and ensu...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Manage comprehensive care for Senior TLC participants, utilizing advanced clinical skills to assess and treat geriatric patients in various settings. Collaborate with healthcare teams to enhance quali...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $160K *

Drive sales growth and profitability by building strong relationships and delivering tailored solutions in a defined territory. Collaborate with cross-functional teams to exceed performance expectatio...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$124K - $158K *

Unlock potential by leading pharmacy operations, ensuring patient safety, and delivering compassionate care. Collaborate with the pharmacy team to enhance performance and compliance while fostering a...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Engage in strategic leadership to enhance wholesale market placements, ensuring optimal coverage and pricing. Oversee national partnerships and market execution while driving team performance and resp...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$80K - $95K *

Analyze and evaluate AI-generated chatbot responses to enhance accuracy and relevance. Collaborate with stakeholders to document requirements and deliver structured assessments that drive improvements...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Staffing

$160K *

Drive enterprise-level implementations of phishing-resistant authentication solutions, leading technical deployments and integrations across various identity platforms while ensuring customer success...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $180K *

Lead strategic health plan implementations and optimize client solutions. Drive cross-functional collaboration, manage complex projects, and enhance operational workflows to ensure successful launches...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$143K - $286K *

Elevate your career by leading Commercial HVAC field quality initiatives, driving warranty performance, and enhancing customer satisfaction through cross-functional collaboration and process improveme...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$80K - $120K *

Shape your career as you take ownership of key accounts, driving sales and building relationships. Collaborate with top performers to modernize government services, while gaining invaluable experience...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$61K - $250K *

Unlock your potential as a financial advisor, building personalized financial plans and nurturing client relationships. Drive growth through networking and exceptional service, while benefiting from c...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Drive business growth by assessing market opportunities, developing strategies, and delivering compelling presentations. Collaborate with teams to align marketing efforts and support client proposals...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.