Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$120K - $145K *

Champion cybersecurity resilience by leading incident response efforts, investigating threats, and collaborating across teams to safeguard enterprise operations against evolving risks and vulnerabilit...

3 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$134K - $209K *

Lead the product strategy and delivery for a comprehensive Workday ecosystem. Manage a team of product managers to enhance HR capabilities, ensuring alignment with enterprise priorities and improving...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Champion the delivery of high-quality critical care by evaluating patients, forming treatment plans, and performing essential procedures in a dynamic healthcare environment, ensuring compliance with t...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Engage in comprehensive cost planning and commercial management for diverse projects, leveraging contractor-side expertise to deliver evidence-based advice and robust cost positions throughout the pro...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$95K - $115K *

Join a team that's dedicated to delivering excellence in electrical project management. Oversee mid-to-large scale projects from inception to completion, ensuring adherence to budget and timelines whi...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$92K - $115K *

Drive client success by managing performance marketing strategies, optimizing Meta campaigns, and crafting compelling copy. Collaborate with clients to enhance relationships and retention while diagno...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Elevate our manufacturing efficiency by procuring and optimizing automation systems. Collaborate on design, oversee installations, and ensure operational excellence across facilities while troubleshoo...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Unlock innovative AI solutions by deploying and scaling advanced workflows. Collaborate with clients to transform business challenges into reliable, AI-driven applications, leveraging cutting-edge tec...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $187K *

Grow your career with a hands-on Engineering Manager role leading a dynamic team to enhance an AI-powered healthcare hiring platform, ensuring quality, reliability, and innovation across multiple tech...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$89K - $151K *

Advance your career by conducting quantitative analytics and modeling projects. Collaborate with stakeholders to develop innovative models and processes, ensuring effective risk management and strateg...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$99K - $152K *

Accelerate progress at the forefront of composite manufacturing, collaborating with cross-functional teams to transform innovative designs into manufacturable products while ensuring quality and effic...

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$118K - $216K *

Reimagine mobile monetization by leveraging AI to build premium user experiences. Drive product innovation and ownership, ensuring reliability for millions of users while expanding into new markets wi...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$220K - $270K *

Join a team that's shaping the future of renewable energy finance by managing complex transactions and driving innovative legal solutions. Collaborate cross-functionally to optimize processes and enha...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$134K - $205K *

Shape the future of energy by leading a structural engineering team on innovative nuclear projects. Collaborate with multidisciplinary teams, mentor engineers, and apply your expertise in structural d...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Technical Services

$142K - $224K *

Lead and oversee strategic projects in a dynamic vaccine manufacturing environment, ensuring alignment with transformation milestones while managing a team of engineers and scientists to enhance opera...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$350K - $500K *

Partner with us to elevate pediatric dentistry through clinical autonomy, advanced technology, and a supportive team. Enjoy a fulfilling career with unlimited earning potential and a focus on patient...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K - $155K *

Unlock your potential by owning the technical design of a comprehensive data platform. Collaborate with cross-functional teams to deliver trustworthy data solutions that enhance product performance an...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$110K - $140K *

Champion the design and execution of eCOA studies, ensuring compliance and data integrity. Collaborate with cross-functional teams to deliver high-quality clinical outcomes while managing multiple pro...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Shape the future of digital experiences by leading Adobe Target implementations, driving A/B testing, personalization, and front-end development. Collaborate with cross-functional teams to enhance exp...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K *

Drive investment strategy and governance, ensuring strong relationships with donors and partners for effective philanthropic outcomes across a $5 billion investment portfolio, while leading a collabor...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's driving innovative marketing strategies to enhance client engagement and growth. Collaborate across functions to optimize performance and build impactful relationships in a dynamic...

Charlotte, NCRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $96K *

Elevate our technology operations by managing infrastructure, cybersecurity, and vendor partnerships. Collaborate with leadership to ensure reliable systems and drive strategic initiatives that align...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Elevate client engagement and drive growth by leading integrated marketing strategies across diverse channels. Collaborate with stakeholders to optimize performance and enhance brand differentiation i...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$201K - $251K *

Champion Quality governance by leading the development and management of Quality Agreements across global operations, ensuring compliance and effective partnerships with internal and external stakehol...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Partner with us to drive sales success in a luxury medical practice, utilizing consultative techniques to enhance client relationships and ensure exceptional patient experiences while collaborating wi...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.