Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$110K - $130K *

Lead estate settlement operations by overseeing a team, ensuring compliance with regulations, and enhancing client outcomes. Drive strategic direction, improve processes, and foster partnerships to de...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$121K - $262K *

Transform credit risk management by leading the Continuous Review program, ensuring compliance and effectiveness across portfolios. Collaborate with executives and teams to identify risks, enhance pro...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$96K - $207K *

Optimize cash management solutions by leveraging expertise in technology and client processes. Collaborate with teams to design and implement strategies that enhance operational efficiency and drive r...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$54K - $111K *

Drive compliance and client satisfaction by managing SBA loan pipelines, ensuring regulatory adherence, and collaborating with stakeholders to facilitate smooth closing processes and documentation man...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$54K - $111K *

Join a dynamic team as a Credit Analyst, responsible for underwriting, monitoring credit, and conducting risk analysis. Develop your skills in financial modeling while ensuring compliance and enhancin...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$121K - $262K *

Drive strategic partnerships and advisory services for business transitions, enhancing client relationships and achieving financial goals through effective collaboration and risk management in wealth...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$54K - $111K *

Champion client success by managing relationships, driving product adoption, and ensuring operational excellence. Leverage your expertise to enhance client engagement, resolve issues, and identify gro...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$74K - $125K *

Analyze and optimize cloud financial management for a federal agency, enhancing cost transparency and performance. Collaborate with technical teams to develop actionable insights and dashboards that d...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$130K - $160K *

Transform the planning landscape by leading integrated sales and operations processes. Drive cross-functional collaboration, develop robust planning models, and ensure alignment on business objectives...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$106K - $295K *

Shape the future of clinical research by leading teams to deliver innovative trials, ensuring compliance and quality while driving recruitment and project success across global studies. Your expertise...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$93K - $232K *

Optimize clinical trial delivery by leading teams to ensure compliance, manage risks, and achieve recruitment targets. Collaborate with stakeholders to enhance project outcomes and support the develop...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$58K - $146K *

Support strategic regulatory engagements by conducting research, analyzing data, and developing insights. Collaborate with senior team members to navigate complex regulatory landscapes and contribute...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$98K - $273K *

Champion end-to-end statistical programming for clinical studies, ensuring compliance with CDISC standards and regulatory submissions. Lead dataset development and provide technical guidance while col...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$62K - $157K *

Advance your career by managing Site Activation activities, ensuring compliance with regulations and SOPs. Collaborate with teams to enhance processes and deliver quality results while maintaining pro...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$62K - $216K *

Champion quality management initiatives by collaborating with global teams to enhance compliance with GCP and regulatory standards, while driving risk assessment and corrective actions to ensure proje...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K *

Oversee the full sales cycle for enterprise SaaS solutions in regulated industries. Drive strategic engagements with C-level executives, navigate complex buying centers, and build compelling business...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Take ownership of developing sales talent and elevating clinical skills across teams. Build trust with healthcare professionals while delivering impactful training and mentoring for both new and exper...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $231K *

Join a team that's dedicated to optimizing Oracle databases for mission-critical medical readiness systems. Collaborate with diverse stakeholders to ensure security, performance, and reliability in a...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $189K *

Lead the charge in coaching agile teams within a scaled framework, ensuring effective planning, execution, and continuous improvement in a collaborative environment while fostering strong stakeholder...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $189K *

Transform agile teams by coaching and facilitating effective Scrum practices, ensuring successful delivery of solutions in a scaled agile environment while fostering strong stakeholder relationships a...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$68K - $143K *

Support audit and compliance efforts for DoD financial systems, ensuring adherence to GAGAS and federal standards. Collaborate with stakeholders to enhance internal controls and audit readiness, drivi...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$94K - $174K *

Elevate quality assurance standards by leading digital compliance and system configuration efforts. Drive operational excellence and embed a robust Quality Culture at the site, ensuring seamless opera...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $213K *

Shape the future of innovative product lines as a Level 4 Agile Product Owner, guiding cross-functional teams to deliver high-value features on schedule while prioritizing stakeholder goals in a fast...

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$80K - $95K *

Transform inpatient coding operations by leading a dedicated team to ensure accurate coding, compliance, and timely billing. Collaborate with clinical and administrative staff to enhance financial per...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Elevate financial excellence by leading financial planning & analysis initiatives, providing strategic insights, and developing executive-level reporting for enhanced decision-making across wealth and...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.