Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$100K - $120K *

Join us to empower community coalitions in preventing youth substance use. As a Project Officer, you'll manage grants, provide technical assistance, and enhance local capacities, all while collaborati...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Drive program operations support by managing logistics, personnel processes, and documentation for a dynamic public health initiative. Collaborate with leadership to enhance efficiency and ensure comp...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $150K *

Shape impactful health initiatives by providing expert project management support to the CDC's Office of the Director, ensuring effective prioritization, coordination, and execution of programs in a d...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Empower innovative design solutions by leading architectural projects, ensuring compliance with codes and standards, and mentoring junior staff. Collaborate with multidisciplinary teams to deliver hig...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$88K - $105K *

Manage the production of innovative designs and specifications for projects, ensuring compliance with codes and standards. Lead a team, oversee project timelines, and support construction efforts whil...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$95K - $115K *

Elevate project outcomes by managing design initiatives from proposal to closeout. Lead a collaborative team to ensure compliance, quality, and client satisfaction while navigating complex healthcare...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$88K - $113K *

Transform proposal management by leading cross-functional teams to deliver high-quality, compliant responses. Drive efficiency through strategic planning, risk management, and collaboration, ensuring...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $149K *

Innovate financial processes by leading NetSuite design and implementation. Collaborate with finance and technical teams to optimize solutions for accounting, planning, and reporting, ensuring data in...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $107K *

Shape the future of pediatric therapy by delivering individualized ABA services in a collaborative clinic environment. Join a dedicated team focused on professional growth and making a meaningful impa...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$83K - $95K *

Empower children by providing tailored occupational therapy in a supportive, play-based environment. Collaborate with a multidisciplinary team to enhance clients' independence and participation in dai...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$190K *

Reimagine consumer experiences by leading product strategy and technology development for digital platforms. Drive innovation and enhance customer engagement through seamless interactions and data-dri...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$125K - $150K *

Lead a dynamic team to enhance client partnerships, driving retention and growth for Fortune 500 and global clients. Your leadership will shape strategies, oversee renewals, and ensure exceptional ser...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$112K - $179K *

Empower a team of RMF professionals by overseeing compliance activities, ensuring adherence to security standards, and driving continuous improvement in risk management processes across the organizati...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$66K - $106K *

Shape the future of technical support by ensuring reliable operation of Shared System Maintainer cycles. Collaborate with developers and analysts to enhance testing environments and troubleshoot issue...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$112K - $179K *

Join a dynamic team to lead security engineering initiatives, ensuring robust protection of cloud infrastructure and sensitive data while driving compliance and mission success in complex federal envi...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$86K - $138K *

Transform documentation practices by leading accessibility initiatives, ensuring compliance with federal standards, and mentoring a team of writers to enhance the quality and efficiency of deliverable...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$112K - $179K *

Lead the design and implementation of enterprise identity security and privileged access management, ensuring robust controls for privileged accounts and sensitive access across systems and cloud envi...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$66K - $106K *

Join us to ensure compliance and security for mainframe systems, overseeing policies and audits while collaborating with teams to enhance information security practices and support client needs effect...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$104K - $166K *

Lead the charge in optimizing and securing mission-critical SQL Server databases on AWS. Provide technical expertise, mentor junior staff, and ensure compliance while collaborating with cross-function...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$66K - $106K *

Shape the future by collaborating with stakeholders to analyze and document system requirements, ensuring clarity and consistency across products while enhancing functionality and user experience in a...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$104K - $166K *

Optimize your career by ensuring the performance and scalability of critical AWS platforms. Collaborate with cross-functional teams to deliver secure, automated solutions while enhancing operational e...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$112K - $179K *

Lead the charge in managing complex IT projects from concept to implementation, ensuring timely delivery and compliance with federal standards. Collaborate with stakeholders to drive project success i...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$112K - $179K *

Join a team that's shaping enterprise security architectures to protect vital information systems. You'll design, govern, and implement security solutions across diverse environments, ensuring complia...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$101K - $126K *

Drive the development and execution of clinical programs, ensuring effective support, education, and coordination across departments while managing health outcomes and utilization data for continuous...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $125K *

Lead the development and submission of federal proposals, managing teams and resources to deliver compliant, compelling responses. Collaborate with cross-functional teams to ensure alignment with cust...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.