Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$110K - $130K *

Lead and transform supply chain operations by overseeing daily processes, ensuring quality standards, and developing team capabilities to achieve organizational goals and enhance performance...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Transportation

$113K - $142K *

Elevate your career by joining our dynamic team to design, develop, and optimize bioinformatics software tools and systems, ensuring robust functionality and compliance in a fast-paced, innovative env...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Help us drive growth by identifying and securing new clients through tailored software solutions, while collaborating with internal teams to enhance customer experience and achieve sales targets in a...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$204K - $216K *

Unlock potential by designing robust data models that empower AI systems. You will ensure data coherence and quality, bridging knowledge representation and machine learning across diverse communities...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $155K *

Join a team that's dedicated to global security by providing advanced threat hunting and intelligence analysis. Collaborate with top organizations to deliver actionable insights and safeguard environm...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$119K - $186K *

Manage legal services for indirect sourcing, delivering strategic counsel and project management. Negotiate vendor agreements and ensure compliance while collaborating with stakeholders to support bus...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $200K *

Shape the future of internal audit by leading compliance initiatives, managing SOX and MAR activities, and enhancing internal controls across the organization. Collaborate with teams to drive risk man...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$155K - $175K *

Engage and expand channel partnerships to drive revenue growth. Lead strategic initiatives, manage partner programs, and collaborate across teams to achieve business objectives in a fast-paced environ...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Unlock potential by developing innovative deep learning models to enhance financial decision-making. Collaborate with a skilled team to translate complex data science concepts into impactful solutions...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$97K - $145K *

Join a dynamic team to lead physician coding integration initiatives, ensuring operational readiness and compliance. Collaborate across departments to enhance coding practices and drive revenue cycle...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Join us to drive regional sales growth by developing strategies, building a motivated team, and fostering strong customer relationships. Your leadership will be key in achieving financial targets and...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$92K - $125K *

Drive operational excellence in patient access by leading teams, enhancing processes, and fostering collaboration across healthcare facilities. Your leadership will ensure compliance, improve patient...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $130K *

Transform financial strategies by owning revenue forecasting, demand planning, and analytics. Collaborate across functions to drive growth and optimize performance, ensuring data integrity and actiona...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$160K - $200K *

Unlock your potential by leading a dynamic sales team to drive growth and innovation in the healthcare sector. Collaborate with senior leadership to shape market strategies and cultivate talent while...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Lead market sales strategy for the U500 segment, driving growth and customer success while developing high-performing teams and influencing strategic decisions within a collaborative senior leadership...

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$282K - $353K *

Transform the AI landscape by owning technical wins in enterprise deals, leveraging data architecture, and delivering superior AI solutions. Collaborate with executive teams to validate and design inn...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Elevate safety standards by developing EHS processes and systems. Collaborate with stakeholders to ensure compliance, lead safety training, and drive continuous improvement in a high-hazard environmen...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$74K - $96K *

Drive financial excellence by overseeing multi-site operations, enhancing profitability, and partnering with leadership to influence strategic decisions. Leverage your expertise in budgeting and repor...

3 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$156K *

Join a team that's dedicated to providing exceptional nursing care in Labor & Delivery. Utilize your expertise to assess, plan, and implement patient care while collaborating with a supportive team in...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$156K *

Elevate patient care by delivering expert nursing in Labor & Delivery. Utilize critical thinking and clinical skills to ensure optimal outcomes while collaborating with a dedicated team in a dynamic h...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the delivery of transportation infrastructure projects in North Carolina, combining technical expertise, project management, and client engagement to drive strategic growth and innovative solutio...

3 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$284K - $390K *

Lead the charge in high-volume B2B demand generation for a dynamic SaaS product. Collaborate cross-functionally to optimize strategies, enhance sales alignment, and drive measurable results in the SMB...

3 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$74K - $139K *

Unlock your potential by designing and delivering impactful training programs that empower new colleagues in the Employee Health & Benefits sector. Collaborate with teams to enhance learning experienc...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$74K - $139K *

Elevate the learning experience by designing and delivering impactful training programs that empower new colleagues in the Employee Health & Benefits sector, ensuring alignment with organizational goa...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$284K - $390K *

Drive high-volume B2B demand generation for a leading SaaS product, focusing on SMB and lower-mid-market segments. Collaborate cross-functionally to optimize marketing strategies, enhance sales alignm...

3 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.