Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.
North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.
Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.
Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.
Average Salary: $115,032
$110K - $130K *
Lead and transform supply chain operations by overseeing daily processes, ensuring quality standards, and developing team capabilities to achieve organizational goals and enhance performance...
Reposted 3 days ago
Senior Bioinformatics & Genomics Data System Engineer
$113K - $142K *
Elevate your career by joining our dynamic team to design, develop, and optimize bioinformatics software tools and systems, ensuring robust functionality and compliance in a fast-paced, innovative env...
3 days ago
$100K - $140K *
Help us drive growth by identifying and securing new clients through tailored software solutions, while collaborating with internal teams to enhance customer experience and achieve sales targets in a...
3 days ago
Senior AI/ML Data Model Architect
$204K - $216K *
Unlock potential by designing robust data models that empower AI systems. You will ensure data coherence and quality, bridging knowledge representation and machine learning across diverse communities...
Reposted 3 days ago
Sr. Intelligence Analyst II, CAO Elite (Remote)
$100K - $155K *
Join a team that's dedicated to global security by providing advanced threat hunting and intelligence analysis. Collaborate with top organizations to deliver actionable insights and safeguard environm...
3 days ago
Senior Counsel - Indirect Procurement
$119K - $186K *
Manage legal services for indirect sourcing, delivering strategic counsel and project management. Negotiate vendor agreements and ensure compliance while collaborating with stakeholders to support bus...
3 days ago
Internal Audit Director - Skyward Group
$180K - $200K *
Shape the future of internal audit by leading compliance initiatives, managing SOX and MAR activities, and enhancing internal controls across the organization. Collaborate with teams to drive risk man...
3 days ago
$155K - $175K *
Engage and expand channel partnerships to drive revenue growth. Lead strategic initiatives, manage partner programs, and collaborate across teams to achieve business objectives in a fast-paced environ...
3 days ago
Staff Data Scientist, Methodologies
$135K - $160K *
Unlock potential by developing innovative deep learning models to enhance financial decision-making. Collaborate with a skilled team to translate complex data science concepts into impactful solutions...
3 days ago
Director, Client Coding Integration
$97K - $145K *
Join a dynamic team to lead physician coding integration initiatives, ensuring operational readiness and compliance. Collaborate across departments to enhance coding practices and drive revenue cycle...
3 days ago
Senior Account Manager - Industrial Sector
$110K - $130K *
Join us to drive regional sales growth by developing strategies, building a motivated team, and fostering strong customer relationships. Your leadership will be key in achieving financial targets and...
Reposted 3 days ago
Director, Patient Access (Travel)
$92K - $125K *
Drive operational excellence in patient access by leading teams, enhancing processes, and fostering collaboration across healthcare facilities. Your leadership will ensure compliance, improve patient...
3 days ago
$108K - $130K *
Transform financial strategies by owning revenue forecasting, demand planning, and analytics. Collaborate across functions to drive growth and optimize performance, ensuring data integrity and actiona...
3 days ago
Vice President of Sales; U500 (Carolinas/Hybrid)
$160K - $200K *
Unlock your potential by leading a dynamic sales team to drive growth and innovation in the healthcare sector. Collaborate with senior leadership to shape market strategies and cultivate talent while...
3 days ago
Vice President of Sales; U500 (Carolinas/Hybrid)
$160K - $200K *
Lead market sales strategy for the U500 segment, driving growth and customer success while developing high-performing teams and influencing strategic decisions within a collaborative senior leadership...
3 days ago
$282K - $353K *
Transform the AI landscape by owning technical wins in enterprise deals, leveraging data architecture, and delivering superior AI solutions. Collaborate with executive teams to validate and design inn...
Reposted 3 days ago
Health & Safety Professional III - SDF
$80K - $95K *
Elevate safety standards by developing EHS processes and systems. Collaborate with stakeholders to ensure compliance, lead safety training, and drive continuous improvement in a high-hazard environmen...
3 days ago
Controller - Multi Location / Multi Account
$74K - $96K *
Drive financial excellence by overseeing multi-site operations, enhancing profitability, and partnering with leadership to influence strategic decisions. Leverage your expertise in budgeting and repor...
3 days ago
Registered Nurse Traveler LDRP
$156K *
Join a team that's dedicated to providing exceptional nursing care in Labor & Delivery. Utilize your expertise to assess, plan, and implement patient care while collaborating with a supportive team in...
3 days ago
Registered Nurse Traveler LDRP
$156K *
Elevate patient care by delivering expert nursing in Labor & Delivery. Utilize critical thinking and clinical skills to ensure optimal outcomes while collaborating with a dedicated team in a dynamic h...
3 days ago
Senior Transportation Design Manager
$110K - $130K *
Lead the delivery of transportation infrastructure projects in North Carolina, combining technical expertise, project management, and client engagement to drive strategic growth and innovative solutio...
3 days ago
Senior Director, Demand Generation Strategy
$284K - $390K *
Lead the charge in high-volume B2B demand generation for a dynamic SaaS product. Collaborate cross-functionally to optimize strategies, enhance sales alignment, and drive measurable results in the SMB...
3 days ago
Learning Consultant, Employee Health & Benefits
$74K - $139K *
Unlock your potential by designing and delivering impactful training programs that empower new colleagues in the Employee Health & Benefits sector. Collaborate with teams to enhance learning experienc...
3 days ago
Learning Consultant, Employee Health & Benefits
$74K - $139K *
Elevate the learning experience by designing and delivering impactful training programs that empower new colleagues in the Employee Health & Benefits sector, ensuring alignment with organizational goa...
3 days ago
Senior Director, Demand Generation Strategy
$284K - $390K *
Drive high-volume B2B demand generation for a leading SaaS product, focusing on SMB and lower-mid-market segments. Collaborate cross-functionally to optimize marketing strategies, enhance sales alignm...
3 days ago
What types of $100K-plus jobs can I find in North Carolina?
Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.
Which North Carolina cities have high-paying job opportunities?
Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.
Are North Carolina jobs on Ladders vetted?
Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.
Can I find remote or hybrid jobs based in North Carolina?
Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.
How often should I check for new North Carolina jobs?
Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.