Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $115,032

Sort By: Relevance

$80K - $95K *

Transform operations by leading a dynamic team to optimize inventory flow, ensuring efficiency and safety while meeting performance targets in a fast-paced distribution environment...

2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$95K - $115K *

Transform business performance by leading financial forecasting, mentoring talent, and delivering actionable insights through cross-functional collaboration and strategic analysis...

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Unlock potential by driving enterprise sales through consultative approaches, managing complex deals with multiple stakeholders, and leveraging a proven sales methodology to achieve targets and foster...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$86K - $148K *

Drive impactful data science initiatives by transforming complex data into actionable insights. Collaborate with cross-functional teams to develop, evaluate, and deploy machine learning models that en...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Business Services

$98K - $134K *

Join our team to drive revenue growth by acquiring new accounts and fostering relationships. You'll engage with key prospects, execute business development strategies, and collaborate cross-functional...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$165K - $200K *

Transform captive program management by driving portfolio growth, enhancing underwriting practices, and fostering strong partner relationships. Join a dynamic team to shape innovative solutions and de...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$94K - $102K *

Drive your career with a hands-on role coordinating customer security and AI assessments. Collaborate across teams to streamline processes, enhance communication, and ensure timely responses, enabling...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Lead and develop maintenance teams across multiple distribution centers, ensuring operational efficiency and safety. Oversee mechanical systems, budget planning, and collaborate on supply chain strate...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Elevate your career by leading the Software Bill of Materials (SBOM) program, enhancing software asset management, and collaborating across teams to ensure compliance, security, and transparency in so...

2 days ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Take ownership of the entire land life-cycle, from acquisition to development, ensuring efficient management of properties and projects while maximizing profitability and fostering local relationships...

2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Join a pioneering team driving sales growth in the data center segment. You'll develop strategies, manage key accounts, and lead a virtual team to enhance customer satisfaction and deliver value in a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$111K - $167K *

Join a team that's driving healthcare transformation by leading client integration initiatives. Collaborate across departments to ensure seamless transitions, operational readiness, and long-term succ...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $200K *

Champion the resolution of complex technical issues for clients, leveraging expertise in Linux, networking, and cloud environments. Collaborate with teams to enhance service delivery and operational c...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$104K - $144K *

Unlock potential by serving as a consultative wound care expert, educating clinicians, driving product adoption, and managing accounts to enhance patient healing and business growth in a dynamic healt...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $316K *

Lead a high-performing platform engineering organization to deliver secure, reliable infrastructure services globally. Drive strategy, execution, and operational management across cloud, AI, and core...

RemoteRemote

Reposted 2 days ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Collaborate with clients to design, build, and integrate Power BI solutions, enhancing dashboard UI/UX and driving data insights through effective team engagement and innovative data modeling techniqu...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform organizational culture and performance by leading HR initiatives across multiple sites, partnering with leadership to align people strategies with business goals, and enhancing employee expe...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$112K - $189K *

Join us to ensure safe, effective medication therapy while advancing pharmaceutical care. Collaborate with healthcare teams, educate future practitioners, and support drug-related research to optimize...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Join a dynamic team to drive the development of a cutting-edge marketplace, enhancing provider products and economic incentives while collaborating closely with engineering and operations to transform...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Lead the design and governance of clinical ontologies and terminology services, ensuring data quality and alignment with product needs. Collaborate cross-functionally to enhance data normalization and...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$192K - $288K *

Join a team that's driving strategic initiatives in Neuroscience and Oncology. In this pivotal role, you'll partner with leadership to enhance operations, manage budgets, and streamline workforce plan...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$118K - $134K *

Unlock potential by driving innovative software solutions in a collaborative, fast-paced environment. Contribute to modernizing business applications while working closely with IT and business teams t...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $145K *

Unlock potential by bridging business needs with technical solutions. Collaborate with stakeholders to define requirements, manage product backlogs, and ensure successful delivery of ServiceNow capabi...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$230K - $345K *

Shape the future of late-stage oncology clinical trials by leading strategic initiatives, ensuring operational excellence, and fostering cross-functional partnerships to drive successful trial executi...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform the renewable energy landscape by managing data portfolios, analyzing project performance, and enhancing financial reporting. Collaborate with cross-functional teams to drive strategic energ...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.