Explore North Carolina Jobs Paying $100K or More

Discover professional opportunities across North Carolina with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking their next career move, from senior individual-contributor positions to executive leadership. Explore openings in major employment centers such as Charlotte, Raleigh, Durham, and Greensboro, as well as opportunities across the state.

Find Opportunities Across North Carolina

North Carolina offers a diverse job market shaped by financial services, technology, healthcare, life sciences, manufacturing, and professional services. Charlotte is a major hub for banking and corporate leadership, while the Raleigh-Durham region is known for technology, research, healthcare, and life sciences. Opportunities may also be available in Greensboro, Winston-Salem, Asheville, and other communities.

Explore Senior Roles Across Industries

Search for experienced-level roles in areas such as technology, finance, operations, sales, marketing, healthcare, engineering, and general management. Job titles, qualifications, work arrangements, and compensation vary by employer. Review each listing for details and identify opportunities that match your background and career goals.

Advance Your Career With Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more, helping experienced candidates explore opportunities aligned with their expertise. Use this page to browse North Carolina openings, compare roles, and discover your next step. Listings and availability change, so check back regularly for new opportunities.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,632

Sort By: Relevance

$126K - $290K *

Contribute to innovative software solutions for enterprise storage systems. Leverage your expertise in C++ and Linux to design, develop, and troubleshoot high-performance applications while collaborat...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Unlock potential by leading the strategy and roadmap for a connected care platform, enhancing patient experiences through integrated technology solutions in healthcare settings. Drive product vision...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$94K - $148K *

Lead the charge in transforming complex healthcare supply chain data into actionable insights, dashboards, and models that drive performance improvement and support strategic consulting engagements fo...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join a dynamic team to elevate client relationships and deliver exceptional wealth management services, supporting key investment strategies and ensuring client satisfaction with detailed financial an...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Accelerate our events strategy by managing end-to-end logistics, driving engagement, and optimizing performance to enhance customer relationships and sales opportunities across diverse sectors...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$62K - $100K *

Drive SaaS conversion initiatives by collaborating with teams to assess risks, readiness, and opportunities. Engage with customers to facilitate migrations and ensure effective communication throughou...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$111K - $131K *

Lead the charge in enhancing audit processes within Payment Services, ensuring compliance and risk management. Drive complex audit engagements, collaborate with stakeholders, and support team developm...

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Engage with clients to enhance their cybersecurity resilience by leading incident response efforts, providing expert guidance, and preparing detailed reports to mitigate risks and improve security pos...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Optimize the Digital revenue operations model, driving strategy, governance, and scalable growth through effective pipeline management, sales forecasting, and CRM practices while collaborating across...

2 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$155K - $185K *

Partner with us to lead high-impact projects in healthcare marketing, managing budgets and teams while ensuring creative excellence and strategic alignment. Drive client success through collaboration...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Lead the evolution of Digital revenue operations, driving strategy, governance, and scalable growth through effective pipeline management, sales forecasting, and technology integration. Collaborate wi...

2 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$88K - $105K *

Transform financial analysis by supporting management teams across regions, focusing on commissions and revenue reporting. Oversee processes, build insightful Power BI reports, and enhance data-driven...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive the technical roadmap for CRA compliance, translating regulatory needs into actionable plans. Collaborate with cross-functional teams to ensure timely delivery while managing stakeholder expecta...

2 days ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Transform engineering leadership by mentoring a skilled team, ensuring compliance with design standards, and overseeing high-quality transmission projects while fostering client relationships and prom...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Drive automation excellence by designing, commissioning, and optimizing industrial control systems globally, collaborating with cross-functional teams to enhance production efficiency and safety acros...

2 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$102K - $176K *

Join a team that's driving process excellence in global manufacturing by optimizing the inflatable bubble extrusion process. Lead initiatives that enhance quality, productivity, and reliability while...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$160K - $246K *

Champion innovative IAM solutions by designing secure software and optimizing SaaS services. Collaborate across teams to embed security practices, conduct threat modeling, and enhance monitoring syste...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$97K - $133K *

Lead the evolution of transaction systems by bridging business and tech. Drive product backlog prioritization, enhance user experience, and collaborate across teams to ensure scalable, automated solut...

2 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$75K - $94K *

Shape exceptional client experiences by leading AV production and design projects. Collaborate across sectors to ensure successful event execution while building lasting relationships and maintaining...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$80K - $95K *

Drive growth by building relationships with healthcare providers in a 50-mile radius. Leverage your sales expertise to expand access to specialized vascular care and enhance community partnerships whi...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead the development of AI-driven document extraction solutions, ensuring accuracy and efficiency. Collaborate with cross-functional teams to prioritize features and manage product roadmaps, driving i...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$193K - $238K *

Unlock potential by driving enterprise sales strategies to acquire new clients. Engage with C-level executives, manage key accounts, and exceed revenue goals while advocating for innovative EHS soluti...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$466K - $500K+*

Join a team that's shaping the future of AI by designing and building scalable platforms for large-scale machine learning model training, enhancing performance, and creating user-friendly experiences...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$190K - $250K *

Analyze and evaluate therapeutic opportunities to drive innovation and business development. Collaborate with interdisciplinary teams to assess scientific and commercial viability, ensuring alignment...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the charge in enhancing organizational security by developing security frameworks, assessing controls, and collaborating with technical teams to create a resilient security architecture for moder...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K-plus jobs can I find in North Carolina?question toggle

    Listings may include senior and executive opportunities across technology, finance, healthcare, life sciences, manufacturing, sales, operations, engineering, and other professional fields. Availability and requirements vary by employer.

  • Which North Carolina cities have high-paying job opportunities?question toggle

    Opportunities may be found in Charlotte, Raleigh, Durham, Greensboro, Winston-Salem, Asheville, and other parts of the state. The location of each position is shown in its listing.

  • Are North Carolina jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs that pay $100,000 or more. Review each job listing for the employer, qualifications, compensation information, and application details.

  • Can I find remote or hybrid jobs based in North Carolina?question toggle

    Some employers offer remote or hybrid arrangements, but work options differ by role. Check the individual listing for its location and workplace requirements.

  • How often should I check for new North Carolina jobs?question toggle

    Listings change as employers add or fill positions. Check back regularly to see newly available opportunities that match your experience and salary goals.