Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,788

Sort By: Relevance

$145K - $175K *

Strategize and execute marketplace growth initiatives on Amazon and TikTok Shop, driving sales and profitability while managing P&L and aligning with omnichannel objectives. Lead operations, performan...

United StatesRemote

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  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Engage your expertise as a Principal UX Researcher, driving strategic insights and research initiatives across global design teams. Collaborate to enhance user experiences and foster an insight-led cu...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$139K - $163K *

Champion the development of enterprise-scale Generative AI solutions, leveraging expertise in LLMs and RAG architectures. Lead cross-functional teams to design secure, scalable systems while driving i...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$77K - $202K *

Lead the charge in developing and customizing Guidewire applications to enhance insurance operations. Collaborate with clients, mentor junior team members, and leverage technical expertise to deliver...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$179K - $224K *

Engage with partner engineering teams to design and prototype integrations that enhance our AI platform. This role demands hands-on engineering, scalable architecture, and translating findings into im...

United StatesRemote

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  •   5 - 7 years exp.  •   Information Technology

$124K - $280K *

Shape the future of insurance technology by leading Guidewire development initiatives, driving technical design, and coaching teams to deliver innovative solutions that enhance policy, claims, and bil...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$90K - $125K *

Transform complex commercial casualty claims management by leveraging your expertise in construction-related exposures and litigation. Collaborate with a dedicated team to deliver exceptional outcomes...

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  •   8 - 10 years exp.  •   Finance & Insurance

$144K - $240K *

Transform healthcare delivery by leading strategic initiatives and optimizing infusion services. Drive client success through expert guidance, operational excellence, and innovative solutions, ensurin...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$130K - $150K *

Drive growth and strategy for key telehealth categories by leveraging market insights, customer feedback, and cross-functional collaboration to enhance performance and deliver exceptional customer exp...

United StatesRemote

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  •   5 - 7 years exp.  •   Healthcare

$145K - $184K *

Empower our communication strategy by collaborating with leaders to create impactful content that enhances customer experience and drives sales momentum across global markets and diverse channels...

Today

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$74K - $87K *

Unlock patient access by managing the insurance verification process, addressing barriers to care, and ensuring seamless coordination among stakeholders to facilitate timely therapy access and support...

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Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $99K *

Unlock the potential of marketing operations by managing our MarTech stack, optimizing processes, and collaborating across teams to drive growth and efficiency in marketing initiatives...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Lead compliance efforts in marketing by ensuring all materials meet legal standards. Collaborate with cross-functional teams to apply guidelines effectively while maintaining a keen attention to detai...

United StatesRemote

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  •   5 - 7 years exp.  •   Healthcare

$90K - $125K *

Lead the accounting function for multiple management companies, ensuring accurate financial reporting and compliance. Collaborate with clients and teams to enhance processes and deliver exceptional se...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Drive the design and development of complex electromechanical systems, overseeing the entire product lifecycle from concept to production. Collaborate with cross-functional teams to deliver innovative...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $95K *

Join us to lead and enhance imaging services, ensuring high-quality patient care and operational excellence while managing staff, resources, and compliance in a dynamic healthcare environment...

Reposted today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Elevate data solutions by designing and maintaining robust infrastructure to ensure reliable, accessible, and secure organizational data across various systems, enhancing analytics, automation, and in...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$117K - $176K *

Champion our Power Systems portfolio by driving strategy, product launches, and pricing. Collaborate across teams to align offerings with market needs and ensure profitable growth in power distributio...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Join a team that's driving supply chain excellence by resolving critical issues, enhancing supplier performance, and ensuring production continuity through data-driven solutions and cross-functional c...

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  •   Less than 5 years exp.  •   Aerospace & Defense

$190K - $210K *

Collaborate with cross-functional teams to drive clinical biomarker strategy and execution, translating discovery insights into actionable approaches that enhance patient outcomes in early neuroscienc...

United StatesRemote

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  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Take ownership of payroll operations, ensuring accuracy and compliance while leading a team to deliver timely wage payments and manage tax obligations effectively across the organization...

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  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Transform the future of AI development tools by leading a team to create innovative platforms that enhance productivity and streamline workflows for thousands of engineers across Epic's major projects...

Today

  •   8 - 10 years exp.  •   Media

$200K - $250K *

Partner with us to drive growth as our Chief Marketing Officer, leading innovative strategies and systems to generate member acquisition across multiple markets, ensuring sustainable success and perfo...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$71K - $100K *

Transform patient care by delivering expert nursing in a fast-paced, Level 1 Trauma unit. Collaborate with a dedicated team to ensure optimal outcomes for critically injured surgical patients, while f...

Today

  •   Less than 5 years exp.  •   Healthcare

$145K - $180K *

Transform retail operations by serving as the primary SAP POS expert for DoD S/4HANA implementations, ensuring alignment with operational goals and financial reporting while bridging technical teams a...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.