Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,788
Director of Marketplace Channel Management (Amazon & TikTok Shop)
$145K - $175K *
Strategize and execute marketplace growth initiatives on Amazon and TikTok Shop, driving sales and profitability while managing P&L and aligning with omnichannel objectives. Lead operations, performan...
Today
$110K - $130K *
Engage your expertise as a Principal UX Researcher, driving strategic insights and research initiatives across global design teams. Collaborate to enhance user experiences and foster an insight-led cu...
Today
$139K - $163K *
Champion the development of enterprise-scale Generative AI solutions, leveraging expertise in LLMs and RAG architectures. Lead cross-functional teams to design secure, scalable systems while driving i...
Reposted today
Guidewire Digital Developer, Senior Associate
$77K - $202K *
Lead the charge in developing and customizing Guidewire applications to enhance insurance operations. Collaborate with clients, mentor junior team members, and leverage technical expertise to deliver...
Today
Forward Deployed Engineer, Ecosystem
$179K - $224K *
Engage with partner engineering teams to design and prototype integrations that enhance our AI platform. This role demands hands-on engineering, scalable architecture, and translating findings into im...
Reposted today
Guidewire Technical Lead, Senior Manager
$124K - $280K *
Shape the future of insurance technology by leading Guidewire development initiatives, driving technical design, and coaching teams to deliver innovative solutions that enhance policy, claims, and bil...
Today
Senior Claims Specialist/Claims Technical Director - Great American Risk Solutions
$90K - $125K *
Transform complex commercial casualty claims management by leveraging your expertise in construction-related exposures and litigation. Collaborate with a dedicated team to deliver exceptional outcomes...
Today
Associate Vice President - Strategic Accounts & Client Success - Remote
$144K - $240K *
Transform healthcare delivery by leading strategic initiatives and optimizing infusion services. Drive client success through expert guidance, operational excellence, and innovative solutions, ensurin...
Today
Category Growth Manager, Women's Hormones
$130K - $150K *
Drive growth and strategy for key telehealth categories by leveraging market insights, customer feedback, and cross-functional collaboration to enhance performance and deliver exceptional customer exp...
Today
Communications Manager - Sales Activation & Scale
$145K - $184K *
Empower our communication strategy by collaborating with leaders to create impactful content that enhances customer experience and drives sales momentum across global markets and diverse channels...
Today
Access Manager - Healthcare Claims, PAs, Reimbursement & Appeals
$74K - $87K *
Unlock patient access by managing the insurance verification process, addressing barriers to care, and ensuring seamless coordination among stakeholders to facilitate timely therapy access and support...
Today
Senior Marketing Operations Specialist
$72K - $99K *
Unlock the potential of marketing operations by managing our MarTech stack, optimizing processes, and collaborating across teams to drive growth and efficiency in marketing initiatives...
Today
Sr. Manager, Marketing Compliance
$110K - $130K *
Lead compliance efforts in marketing by ensuring all materials meet legal standards. Collaborate with cross-functional teams to apply guidelines effectively while maintaining a keen attention to detai...
Today
$90K - $125K *
Lead the accounting function for multiple management companies, ensuring accurate financial reporting and compliance. Collaborate with clients and teams to enhance processes and deliver exceptional se...
Today
$95K - $115K *
Drive the design and development of complex electromechanical systems, overseeing the entire product lifecycle from concept to production. Collaborate with cross-functional teams to deliver innovative...
Today
Manager - Imaging [On-site - Pinehurst, NC]
$80K - $95K *
Join us to lead and enhance imaging services, ensuring high-quality patient care and operational excellence while managing staff, resources, and compliance in a dynamic healthcare environment...
Reposted today
Data Engineer [On-site - Pinehurst, NC]
$95K - $115K *
Elevate data solutions by designing and maintaining robust infrastructure to ensure reliable, accessible, and secure organizational data across various systems, enhancing analytics, automation, and in...
Reposted today
Offer Manager, Low Voltage Systems
$117K - $176K *
Champion our Power Systems portfolio by driving strategy, product launches, and pricing. Collaborate across teams to align offerings with market needs and ensure profitable growth in power distributio...
Today
Principal Specialist, Supply Chain Management (Remote - Puerto Rico)
$100K - $120K *
Join a team that's driving supply chain excellence by resolving critical issues, enhancing supplier performance, and ensuring production continuity through data-driven solutions and cross-functional c...
Today
Principal Scientist/Associate Director, Translational Medicine
$190K - $210K *
Collaborate with cross-functional teams to drive clinical biomarker strategy and execution, translating discovery insights into actionable approaches that enhance patient outcomes in early neuroscienc...
Today
$80K - $95K *
Take ownership of payroll operations, ensuring accuracy and compliance while leading a team to deliver timely wage payments and manage tax obligations effectively across the organization...
Today
Principal Engineer, AI Platform
$150K - $180K *
Transform the future of AI development tools by leading a team to create innovative platforms that enhance productivity and streamline workflows for thousands of engineers across Epic's major projects...
Today
$200K - $250K *
Partner with us to drive growth as our Chief Marketing Officer, leading innovative strategies and systems to generate member acquisition across multiple markets, ensuring sustainable success and perfo...
Today
RN Clinical Nurse II- Surgical/Trauma Critical Care Unit Stepdown Focus
$71K - $100K *
Transform patient care by delivering expert nursing in a fast-paced, Level 1 Trauma unit. Collaborate with a dedicated team to ensure optimal outcomes for critically injured surgical patients, while f...
Today
Principal SAP Retail POS Consultant
$145K - $180K *
Transform retail operations by serving as the primary SAP POS expert for DoD S/4HANA implementations, ensuring alignment with operational goals and financial reporting while bridging technical teams a...
Today
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.