Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,696

Sort By: Relevance

$210K - $250K *

Lead the charge in delivering exceptional clinical care within a collaborative team, enhancing patient outcomes while supporting education and compliance initiatives in a dynamic healthcare environmen...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Lead the product vision and strategy for a cutting-edge cloud service, shaping capabilities and defining AI-driven insights while collaborating with engineering and operations teams to ensure market a...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Join a team that's shaping evidence strategies and insights in health economics and outcomes research. Lead client engagements, oversee analytics, and drive impactful decision-making in biopharma and...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Join a team that's redefining patient care by delivering high-quality, person-centered services in skilled nursing facilities. Enjoy clinical autonomy, flexible scheduling, and the opportunity to make...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Lead the charge in managing land development projects, ensuring quality and profitability while fostering client relationships and identifying new opportunities for growth. Join a dynamic team focused...

Reposted yesterday

  •   5 - 7 years exp.  •   Technical Services

$89K - $137K *

Champion your career by driving software solutions in the education sector. Engage with key decision-makers in K-12 and higher education to expand Lenovo's portfolio, while collaborating with sales te...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Join a team that's shaping the future of software development by leading projects, mentoring engineers, and architecting innovative solutions that enhance performance and meet business goals in a coll...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$79K - $119K *

Join our team to provide essential after-hours clinical support, triage patient needs, and ensure quality care delivery. Collaborate with interdisciplinary teams to enhance patient outcomes in a dynam...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$112K - $197K *

Elevate community health by leading pharmacy operations and patient care initiatives. Drive team performance, ensure compliance, and enhance service delivery while fostering a culture of outreach and...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$84K - $112K *

Unlock potential by providing strategic financial insights to drive partner sales success. Collaborate with cross-functional teams to enhance forecasting, performance tracking, and decision-making in...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$170K - $205K *

Unlock the potential of our Pro offering by leading product strategy and roadmap. Collaborate across teams to enhance customer experiences for short-term rental operators and HOAs, ensuring scalable s...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Hospitality & Recreation

$138K - $214K *

Optimize project outcomes by leading preconstruction efforts for large-scale Data Center initiatives. Drive team performance, manage budgets, and ensure exceptional client relationships while overseei...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$92K - $120K *

Join a dynamic team as a Medical Claims Auditor, ensuring compliance and integrity in healthcare payments. Collaborate with cross-functional teams to identify fraud, waste, and abuse while leveraging...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion client success by managing key relationships and driving strategic initiatives. Lead cross-functional teams to deliver high-quality work while ensuring financial performance and growth for as...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Advance your career by building high-throughput services that power AI workflows. Collaborate with cross-functional teams to design scalable infrastructure and tackle complex challenges in a dynamic e...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Consumer Technology

$95K - $115K *

Transform data quality and integration processes by leading ETL testing initiatives, collaborating with cross-functional teams, and ensuring robust software solutions through hands-on coding and strat...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Inspire a high-performing engineering team by driving strategy, operational excellence, and collaboration across multiple locations. Lead initiatives that foster innovation and professional growth whi...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$175K - $210K *

Lead pioneering evidence generation initiatives to inform oncology product strategies and lifecycle management through cross-functional collaboration and data-driven decision-making...

RemoteRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $138K *

Champion comprehensive urologic care by collaborating with a dynamic team of surgeons and APPs. Focus on inpatient and outpatient management, performing procedures, and enhancing patient outcomes in a...

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Optimize enterprise observability and application performance monitoring by leading a team of engineers. Drive Dynatrace platform strategy, establish monitoring standards, and enhance full-stack visib...

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$99K - $148K *

Elevate patient care by providing neurology services in a collaborative outpatient setting. Enjoy a flexible schedule with no weekends or call, while managing follow-up care for stroke and routine pat...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$177K - $265K *

Join a team that's dedicated to safeguarding player experiences by investigating and combating cheating in games. Leverage your analytical skills to create data-driven reports and collaborate with eng...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Consumer Technology

$150K - $180K *

Lead and grow a high-performing platform engineering team, setting vision and roadmap while collaborating with cross-functional leaders to enhance product velocity and reliability for enterprise custo...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in client strategy and Meta campaign management, ensuring optimal performance and strong relationships. Own a portfolio of accounts, drive results, and proactively solve issues to enha...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$146K - $206K *

Join a dynamic team to build secure customer authentication features, enhancing user experiences across B2C and B2B platforms. Collaborate with engineers to develop backend services and APIs, ensuring...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.