Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$135K - $160K *

Join a dynamic team to architect and implement a next-gen Design System, ensuring consistent, accessible experiences across products. Collaborate with cross-functional teams to drive technical alignme...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$175K - $210K *

Innovate as a strategic technology leader, driving digital transformation and AI initiatives to enhance operational efficiency and business growth while collaborating with executive teams and fosterin...

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$112K - $135K *

Elevate warehouse operations by leading SAP EWM implementations, delivering robust designs and driving project lifecycles while mentoring your team and optimizing execution workflows for high performa...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$140K - $175K *

Lead the charge in building trust through compliance frameworks, guiding customers and teams in navigating security and data protection. Engage directly with clients, translating complex compliance ne...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$500K+*

Pioneer the evolution of Netflix's Compute Platform, driving innovation in distributed systems and AI integration. Lead product strategy, enhance efficiency, and collaborate across teams to ensure rob...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$100K - $130K *

Partner with us to enhance project financial performance and operational excellence. Leverage your expertise in project controls and financial analysis to drive insights, improve practices, and suppor...

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$175K - $210K *

Lead a global team of Solution Consultants in OT/CPS, driving technical pre-sales strategy and customer engagement. Foster a high-performance culture while scaling the business through innovative AI-d...

Philadelphia, PARemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Transform the future of industrial automation by designing innovative hardware solutions. Collaborate with cross-functional teams to develop cutting-edge products, ensuring compliance and optimizing d...

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Transform the future of mobile broadcasting by leading technical operations, ensuring show readiness, and delivering exceptional live production experiences while mentoring teams and managing client r...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Media

$150K - $180K *

Optimize AI infrastructure by designing APIs and resource management systems for GPU clusters. Collaborate with teams to enhance scheduling algorithms and ensure efficient resource allocation, impacti...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Champion the evolution of our billing systems by leading a dynamic engineering team. Drive strategy, ensure accuracy, and collaborate across departments to enhance customer trust as we scale our usage...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$181K - $239K *

Join a team that's driving revenue transformation through AI solutions. You'll lead a high-performing group, architect workflows, and partner with executives to deliver measurable business outcomes ac...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$89K - $105K *

Lead the charge in enhancing customer trust through security assurance and AI governance. This role focuses on maintaining accurate security documentation and optimizing AI agents to support governanc...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$114K - $145K *

Unlock your potential as a Data Engineer, transforming raw data into impactful systems. Collaborate with stakeholders, optimize data architecture, and drive efficiency through automation while managin...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $110K *

Drive the administration and enhancement of Nagios XI monitoring systems, ensuring optimal performance and coverage across diverse environments. Collaborate with IT teams to identify gaps and implemen...

Pennsylvania, USRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Join a team that's driving enterprise AI adoption by building a qualified pipeline through strategic outbound prospecting. Collaborate with Account Executives to engage key stakeholders and facilitate...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in modernizing SaaS solutions by integrating AI and automation to enhance delivery efficiency, scalability, and customer outcomes while supporting complex migration projects and foster...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Join us to lead complex data migration initiatives, focusing on Salesforce CPQ and Billing. Collaborate with clients and teams to design scalable data architectures that drive revenue transformation a...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $178K *

Join us to lead critical safety engineering efforts in support of advanced Nuclear Weapons Programs, leveraging your expertise to develop solutions that meet stringent DoD requirements and ensure miss...

4 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$129K - $210K *

Empower organizations by designing scalable data management solutions, collaborating with customers and partners to drive adoption and success. Act as a key technical advisor, bridging teams to ensure...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$110K - $130K *

Pioneer innovative solutions by partnering with customers and teams to transform AI and HPC requirements into reliable deployments, driving success through technical depth and collaboration across fun...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Join a team that's dedicated to safeguarding sensitive health information while enhancing security across cloud and application environments. As a Senior Security Engineer, you'll design and implement...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$149K - $218K *

Advance the future of optical interconnects by architecting high-speed layouts. Lead full-flow execution from concept to tapeout, tackling complex design challenges while mentoring talent and shaping...

Reposted yesterday

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$124K - $198K *

Transform your career by owning and accelerating Unstructured data protection sales. Leverage your technical expertise to drive growth, engage stakeholders, and win competitive deals in a dynamic, quo...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$120K - $140K *

Join a team that's driving growth in unstructured data protection. Leverage your technical expertise to engage with clients, lead discovery, and close deals while collaborating with sales and engineer...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.