Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$200K - $350K *

Join us to define the next generation of platform software architecture, leading cross-functional teams to create stable interfaces and drive technical decisions that shape the future of AI inference...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Elevate your career by implementing and supporting AWS cloud solutions in a dynamic environment. Collaborate with experts to optimize performance and ensure secure, scalable infrastructure for federal...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$160K - $210K *

Join a team that's driving innovation in cloud security and IoT systems. Collaborate with Fortune 500 clients, providing technical expertise and solutions while traveling extensively to enhance custom...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$151K - $205K *

Discover innovative solutions as you design comprehensive technology architectures that align with client goals. Collaborate with teams to address needs, develop strategies, and ensure successful impl...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Join a team that's dedicated to transforming healthcare data solutions. As a Senior Data Engineer, you'll enhance complex systems, collaborate across departments, and drive analytics to optimize finan...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Solve security challenges by owning and enhancing our security program. Lead CorpSec, SecOps, and compliance efforts while building a robust security culture in a fast-paced, remote environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Transform critical power systems by overseeing installation, maintenance, and troubleshooting of backup generators in data centers, ensuring uninterrupted power supply and optimal uptime for mission-c...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$207K - $310K *

Champion the Solutions Engineering team by driving technical sales strategies, managing performance, and fostering collaboration to meet organizational goals while ensuring customer success and team d...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$86K - $135K *

Transform naval technology by designing cloud solutions and DevSecOps pipelines. Leverage your expertise in AWS and systems integration to support U.S. Navy programs, ensuring robust software developm...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$171K - $257K *

Lead the charge in Cyber Resilience solutions, guiding sales teams and partners to align business objectives with innovative technology. Collaborate cross-functionally to enhance market strategies and...

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$94K - $293K *

Explore innovative solutions in enterprise AI by architecting multi-agent systems. Lead engagements, collaborate with clients, and shape methodologies while driving technical excellence in AI-native a...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$94K - $293K *

Empower innovation by architecting AI-native systems, leading engineering teams, and translating complex AI capabilities into business value while ensuring seamless integration with existing infrastru...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

Innovate your career by leading SaaS modernization projects, enhancing delivery efficiency through AI and automation. Drive customer success by transforming legacy systems into scalable, sustainable s...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$131K - $219K *

Join a team that's redefining cybersecurity in the energy sector. You'll lead complex projects, develop standards, and automate processes to enhance efficiency and security across global Grid Automati...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$158K - $198K *

Transform enterprise storage management by leading a specialized team in z/OS environments. Oversee IBM storage systems, ensuring security, performance, and availability while collaborating closely wi...

3 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$170K - $230K *

Join a team that's redefining SoC design by owning subsystem development, integrating third-party IP, and optimizing PPA for next-gen architectures. Contribute across all design stages and drive impac...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Champion compliance and security excellence by driving NIST 800-53 and FedRAMP initiatives. Partner with clients to ensure federal authorization, author vital documents, and manage multiple A&A projec...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$157K - $283K *

Elevate your career by managing complex R&D projects in wireless communication, focusing on 6G security for military applications. Collaborate with multidisciplinary teams to deliver innovative soluti...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$114K - $252K *

Shape the future of cloud infrastructure by optimizing AWS GovCloud environments. Leverage your expertise in architecture and security compliance while empowering technical teams toward innovation and...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$84K - $124K *

Drive the evolution of Cyber Defense by engineering and automating security operations, enhancing incident response, and maintaining enterprise security platforms to ensure robust protection and swift...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$145K - $175K *

Transform the future of computing by owning the Linux kernel driver for our innovative Fabric accelerator. Collaborate with cross-functional teams to ensure seamless pre-silicon development and bring...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $240K *

Lead the charge in shaping data architecture strategies, driving innovation across platforms, and mentoring teams to optimize data governance and AI integration for scalable solutions that deliver mea...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$240K - $300K *

Empower strategic partnerships across the Eastern U.S. to drive revenue growth. Build and manage a partner-sourced pipeline, enhance customer engagement, and accelerate deal closures through collabora...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$250K - $275K *

Empower your career as a Senior Client Solutions Architect, guiding clients through complex tech implementations. Lead solution strategy from design to execution while mentoring technical teams and co...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's redefining application security by guiding customers through complex evaluations. Leverage your expertise in offensive security to build relationships, deliver impactful demos, and...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.