Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.
Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.
Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.
Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.
Director of Engineering, Webapp & AI Attack
$290K - $340K *
Lead and inspire engineering teams to develop cutting-edge web and AI security solutions. Drive strategy, execution, and organizational health while fostering a culture of innovation and accountabilit...
2 days ago
$120K - $150K *
Lead the charge in delivering complex integrations for clients, embedding with their teams to build reusable assets against our API. Transform vague requests into actionable plans while enhancing depl...
3 weeks ago
Senior Solutions Engineer - Major Accounts
$148K - $222K *
Unlock your potential as a Senior Solutions Engineer, driving sales success by leveraging technical expertise to address customer needs and deliver innovative F5 solutions. Collaborate with teams to e...
2 weeks ago
Clinical AI Technical Integration Specialist
$110K - $130K *
Unlock potential by driving technical integration and validation for Ambient AI Scribe initiatives. Collaborate with clinical teams to enhance workflows, troubleshoot issues, and ensure operational re...
1 week ago
Engineer - Strategic Programs (Hybrid)
$84K - $116K *
Lead the charge in enhancing utility infrastructure through technical expertise, engineering studies, and collaborative project execution, ensuring safety and compliance while driving improvements in...
Today
Senior Genetec System Administrator
$95K - $115K *
Lead the global rollout of a physical security platform, managing Genetec Security Center configurations and troubleshooting across 100+ locations. Collaborate with local teams to ensure seamless inte...
Today
Senior Architect Data Management
$120K - $140K *
Elevate data management strategies by leading the design and governance of enterprise data ecosystems. Drive innovation through advanced tools, ensuring data integrity and compliance while collaborati...
1 week ago
Senior Architect Data Management
$110K - $130K *
Champion the design and governance of enterprise data ecosystems, driving data management strategies and ensuring compliance. Lead teams in implementing advanced tools for scalable, secure data soluti...
1 week ago
$120K - $145K *
Join a dynamic team to build and automate security controls across our infrastructure. You'll manage host hardening, vulnerability assessments, and compliance, leveraging AI tools to enhance security...
4 weeks ago
Principal Sales Engineer - Federal
$175K - $251K *
Transform the future of public sector security by leading technical sales, engaging with Federal entities, and driving innovative solutions for Zero Trust transformations through expert guidance and c...
Reposted today
Business Development Manager, Government
$147K - $203K *
Lead the charge in driving sales strategies for government sectors, managing complex sales cycles, and fostering relationships with key decision-makers to achieve revenue growth and budget targets...
1 week ago
Chief Data & Interoperability Architect
$107K - $195K *
Shape the future of healthcare data interoperability by leading architecture design and integration strategies for federal health programs, ensuring seamless data flow and compliance with industry sta...
Today
Principal Consultant - Service Cloud Voice Architect
$135K - $160K *
Lead the design and delivery of innovative Service Cloud Voice solutions, guiding clients through contact center modernization and AI adoption. Collaborate with teams to create scalable, secure archit...
3 weeks ago
$90K - $110K *
Join a team that's redefining change management in healthcare. Support the adoption of innovative informatics solutions, ensuring seamless transitions and user readiness across the Veterans Health Adm...
3 weeks ago
Technical SME - Data Architecture / Data Ware
$110K - $130K *
Empower your career with senior-level expertise in data architecture and warehousing. Drive data integration and management, ensuring effective solutions for Occupational Environmental Health practice...
1 month ago
Clinical Informatics Integrator
$110K - $130K *
Lead the charge in managing informatics projects from planning to delivery, ensuring timely decision-making and risk management. Collaborate with cross-functional teams to enhance health information e...
4 weeks ago
Solutions Architect - SLED (East)
$120K - $145K *
Champion the modernization of SLED organizations by guiding them through technical evaluations and deployments of GitLab's DevSecOps platform, ensuring compliance and enhancing service delivery across...
1 week ago
Enterprise Architect - Consumer Banking & Marketing
$139K - $232K *
Unlock potential by providing enterprise architecture leadership for Retail and Consumer Banking. Shape technology strategies and roadmaps across various banking capabilities, ensuring alignment with...
6 days ago
Security Engineer, Vulnerability Management & Security Operations
$120K - $145K *
Lead our vulnerability management and security operations program, shaping it from the ground up. Collaborate with a small Trust team to enhance our security posture and ensure compliance while automa...
1 week ago
Director, AI Platforms, Global
$200K - $210K *
Join a dynamic team to lead AI platform strategy and operations, ensuring seamless access and governance while driving enterprise-wide adoption and continuous improvement of innovative AI solutions...
1 week ago
Senior Security Consultant, Operational Technologies (OT)
$100K - $175K *
Grow expertise in Operational Technology security, leading critical engagements across industrial systems. Collaborate on advanced methodologies while mentoring others and contributing to pivotal rese...
Reposted 3 weeks ago
$160K - $200K *
Drive enterprise sales by creating pipeline, closing complex contracts, and building strategic relationships. Collaborate with leadership to scale revenue and develop a repeatable sales motion in the...
3 weeks ago
Infrastructure Lead, DoD / DoW
$163K - $203K *
Shape the future of defense infrastructure by leading technical engagements and ensuring successful project execution. Collaborate with stakeholders to deliver innovative solutions that meet mission-c...
3 days ago
Engineer III, OT/ICS Cybersecurity & Controls
$110K - $130K *
Lead the charge in securing and optimizing OT/ICS networks for energy systems. As a senior engineer, you'll design network architectures, manage cybersecurity compliance, and collaborate with cross-fu...
3 weeks ago
Data Center Acquisition Manager
$190K - $215K *
Manage the entire deal process for data center acquisitions, engaging stakeholders, negotiating terms, and driving transactions to closure. Handle multiple deals with precision while optimizing commer...
Reposted 3 weeks ago
What types of $100K+ jobs can I find in Pennsylvania?
Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.
Which Pennsylvania cities have professional job opportunities?
Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.
Are these Pennsylvania jobs vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.
Can I find remote or hybrid jobs in Pennsylvania?
Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.