Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$108K - $130K *

Advance system design excellence by collaborating with cross-functional teams, ensuring quality and timely delivery of specifications, and managing technical risks while driving continuous improvement...

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$105K - $115K *

Optimize security measures by leading technical solutions to mitigate information risks. Ensure compliance with corporate policies and oversee incident response, safeguarding all computing platforms a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$135K - $160K *

Lead enterprise architecture strategy across Oracle CX, ERP, HCM, and SCM Cloud. Collaborate with stakeholders to develop scalable solutions, ensuring alignment with business capabilities and technolo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Staffing

$130K - $160K *

Shape the future of retail by architecting innovative AI solutions that drive business success. Collaborate with cross-functional teams to integrate open-source technologies and enhance operational ef...

Philadelphia, PARemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$170K - $240K *

Unlock potential by serving as a strategic technical advisor for key enterprise customers, guiding architecture decisions and aligning technical plans with business outcomes to ensure successful imple...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Shape the future of operational technology security by leading the design and enhancement of robust security controls. Collaborate across teams to ensure a resilient environment, minimizing risks whil...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $170K *

Innovate the future of enterprise data architecture by leading strategic design, governance, and analytics initiatives. Drive scalable solutions across financial, operational, and HR platforms while e...

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$140K - $170K *

Lead the charge in designing and governing enterprise data architecture, ensuring robust data governance and analytics solutions across multiple platforms while collaborating with stakeholders to enha...

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$140K - $170K *

Shape the future of enterprise data architecture by leading strategic design, governance, and analytics initiatives. Collaborate with stakeholders to deliver scalable solutions across financial, opera...

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$140K - $170K *

Lead the design and governance of enterprise data architecture, ensuring robust analytics and data solutions across the organization. Collaborate with stakeholders to enhance data quality and drive st...

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$125K - $150K *

Lead the charge in architecting innovative Salesforce solutions, guiding teams through technical design and delivery while ensuring quality and efficiency. Collaborate with stakeholders to meet client...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Champion enterprise data architecture by establishing standards and a unified data catalog. Collaborate across teams to define metrics and ensure data governance, driving alignment and clarity in a ha...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in enhancing organizational security by developing security frameworks, assessing controls, and collaborating with technical teams to create a resilient security architecture for moder...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$282K - $353K *

Transform the AI landscape by owning technical wins in enterprise deals, leveraging data architecture, and delivering superior AI solutions. Collaborate with executive teams to validate and design inn...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Grow with us as you manage and scale cutting-edge infrastructure, ensuring optimal performance for a rapidly expanding system serving millions of requests daily. Collaborate in a hands-on role where y...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Transform your career with a pivotal role in advanced network support, collaborating on strategic technology plans and enhancing operational effectiveness. Lead initiatives, troubleshoot complex issue...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$77K - $176K *

Join a team that's shaping the future of network connectivity by designing, implementing, and maintaining advanced SD-WAN solutions. Play a key role in ensuring secure and optimized network performanc...

5 days ago

  •   Less than 5 years exp.  •   Business Services

$77K - $176K *

Unlock network potential by designing and maintaining SD-WAN solutions, ensuring secure and optimized connectivity across diverse environments while troubleshooting complex issues and enhancing perfor...

5 days ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Drive customer success as a technical expert, partnering to optimize IoT deployments. Your strategic insights will enhance service adoption and expand account growth, delivering tangible business outc...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$77K - $118K *

Drive the evolution of scalable, secure platforms by architecting solutions that enhance network intelligence and application delivery, collaborating with cross-functional teams to optimize performanc...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Elevate customer experiences by leading a team of engineers, providing strategic insights, and implementing innovative solutions in growth engineering and digital marketing for impactful delivery serv...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Shape the future of avionics sales by leading business development efforts, engaging military and commercial aerospace customers, and driving strategic growth in the Americas through innovative test s...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$110K - $140K *

Unlock the potential of our partner ecosystem by designing and delivering impactful enablement programs that elevate partner performance through engaging, high-quality training experiences...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $175K *

Join us to define and drive the enterprise cloud database strategy, leading architecture and modernization efforts to create scalable, reliable solutions for healthcare applications serving millions o...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Lead the charge in delivering innovative solutions as a Solutions Architect, guiding teams and customers through technical challenges while maximizing mission impact and enhancing customer experiences...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.