Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
$150K - $180K *
Engage with key healthcare clients to drive strategic account management, fostering relationships and delivering tailored solutions across GE HealthCare’s diverse portfolio, while leading cross-functi...
1 week ago
Principal Embedded Software Engineer
$130K - $155K *
Lead the charge in creating cutting-edge embedded software solutions for autonomous mobile robotics. Drive technical excellence, oversee collaborative engineering efforts, and ensure high reliability...
Reposted 3 weeks ago
Director of Technology/Security
$120K - $145K *
Join a dynamic team to architect and oversee cybersecurity and integration for a statewide Health Information Exchange, ensuring secure data management and compliance with healthcare standards while l...
1 week ago
Director of Technology/Security
$120K - $145K *
Lead the technical architecture and cybersecurity strategy for a statewide Health Information Exchange, ensuring secure integration and compliance with healthcare privacy standards while managing vend...
1 week ago
Director of Technology/Security
$125K - $150K *
Lead the charge in directing technical architecture and cybersecurity for a statewide Health Information Exchange, ensuring secure integration and compliance with healthcare privacy standards while ma...
1 week ago
Director of Technology/Security
$120K - $145K *
Lead the technical architecture and cybersecurity strategy for a statewide Health Information Exchange, ensuring secure integration and compliance while guiding multidisciplinary teams and vendors to...
1 week ago
Director of Technology/Security
$120K - $145K *
Unlock the potential of health data by leading the architecture and cybersecurity for a statewide Health Information Exchange, ensuring secure integration and compliance while guiding a multidisciplin...
1 week ago
$85K - $120K *
Optimize the software development process by contributing to product-focused projects, addressing coding, debugging, automated testing, and performance enhancement to ensure scalable and efficient sof...
Reposted yesterday
$85K - $120K *
Unlock innovation as a hands-on Software Engineer, driving Proofs-of-Concept and full software development cycles. Collaborate with senior engineers to explore emerging technologies while ensuring pro...
4 weeks ago
$110K - $130K *
Drive profitable growth and market share by leading a high-performing sales team, building strategic customer relationships, and collaborating cross-functionally to enhance commercial performance and...
2 days ago
$110K - $130K *
Optimize project delivery by leading enterprise SaaS implementations for utility clients. Build strong client relationships, manage competing priorities, and ensure successful project outcomes across...
Reposted 2 weeks ago
ServiceNow CMDB Operations Developer
$75K - $158K *
Bring your expertise to optimize and maintain the ServiceNow CMDB, ensuring data accuracy and reliability. Collaborate with IT teams to enhance service delivery across 187 bases, supporting a high-qua...
Reposted 2 weeks ago
$109K - $129K *
Take ownership of product development in a dynamic, cross-functional team. Drive AI-assisted innovation from problem framing to launch, focusing on customer outcomes and strategic impact in a hyper-ag...
5 days ago
$180K - $240K *
Innovate by bridging software engineering and customer delivery, shaping core product capabilities while deploying AI solutions. Collaborate with teams to translate needs into robust systems, ensuring...
Yesterday
Senior Director, Global Cyber Defense
$349K - $437K *
Lead and innovate the global Cyber Defense organization, enhancing security posture through proactive threat identification, incident response, and strategic planning while collaborating with senior l...
6 days ago
Workday Financials Senior Principal Consultant, Record to Report - Global AMS
$128K - $192K *
The Workday Financials Senior Principal Consultant, Record to Report is a dynamic professional responsible for leading the Financials workstream and ensuring operational efficiency in Workday engageme...
Reposted 2 days ago
Software Engineer - Technology
$108K - $115K *
Unlock your potential as a full stack engineer, collaborating in an agile team to develop innovative applications and features, while leveraging cutting-edge AI technologies to enhance product offerin...
1 week ago
$115K - $192K *
Engineer trusted, reusable data products by transforming architectural designs and business requirements into production-grade solutions. Collaborate with cross-functional teams to deliver innovative...
2 weeks ago
Forward Deployed Palantir Solutions Lead
$192K - $338K *
Lead transformative AI and data strategies for enterprise accounts, driving value through hands-on engagement and technical leadership. Collaborate with executives to deliver tailored solutions that e...
2 days ago
Senior Public Relations Manager
$157K - $174K *
Drive impactful media strategies and foster PR excellence across U.S. and Israel. Collaborate with leadership to establish authority in AI security and exposure management while utilizing innovative A...
Reposted yesterday
Experienced Info Security Engineer (AI Automation)
$84K - $187K *
Join the AI Automation team to innovate and implement AI solutions that enhance efficiency and security. Collaborate with experts to build automations, connect systems, and experiment with cutting-edg...
5 days ago
Solutions Engineer - M365 Copilot & Agents
$150K - $207K *
Partner with us to drive enterprise AI adoption by assessing, deploying, and securing Microsoft 365 Copilot and Agent 365 capabilities. Leverage your expertise to enhance customer environments and ens...
3 weeks ago
$80K - $115K *
Engage with customers to ensure successful onboarding and implementation of solutions. Collaborate across teams to drive value, manage projects, and advocate for customer needs while building trusted...
5 days ago
$110K - $130K *
Elevate your career by collaborating with cross-functional teams to enhance business operations, streamline processes, and drive value through effective analysis and documentation. Your expertise will...
3 weeks ago
Account Executive - Workday Smart Products
$100K - $120K *
Lead business development initiatives by building strategic partnerships and networks. Drive revenue growth through consultative selling and effective stakeholder management while fostering a collabor...
Yesterday
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.