Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Business Transformation Manager
$107K - $199K *
Elevate your career by leading strategic initiatives that enhance operational efficiency. Collaborate across functions to drive impactful change, optimize processes, and mentor associates while delive...
Yesterday
Senior Manager, Operational Technology Architecture
$175K - $250K *
Lead the architectural strategy for Operational Technology, ensuring integration with enterprise objectives. Strategically influence technical decisions and guide multi-disciplinary teams in deliverin...
Reposted yesterday
Associate Director, Regulatory Project Management (remote)
$136K - $220K *
Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...
Reposted yesterday
Sales Representative, Pain - Long Beach, CA
$72K - $108K *
Unlock potential by developing strategic sales plans and fostering relationships to achieve quarterly goals. Drive impactful presentations and enhance product awareness while ensuring compliance with...
Yesterday
Associate Director, US Pricing Contract Operations & Rebate Processing
$177K - $221K *
Lead the charge in optimizing pricing contract operations, ensuring compliance and strategic insights for government and provider contracts. Collaborate cross-functionally to enhance business outcomes...
Yesterday
Partner Development Manager, Alliances and Channels
$125K - $150K *
Drive strategic partnerships and revenue growth by fostering relationships with partners and sales teams. Lead joint marketing initiatives and advocate for partner success to enhance collaboration and...
Reposted yesterday
$150K - $180K *
Transform the future of businesses by leading operational strategies, enhancing efficiency, and driving growth. Collaborate with executive teams to create value, monitor performance, and ensure resour...
Reposted yesterday
Senior Manager, Membership Operations
$94K - $148K *
Transform membership data quality by leading a team of analysts to enhance processes, ensure accuracy, and align with pharma partners. Drive performance metrics and implement improvements to meet evol...
Yesterday
Enterprise Account Executive, Acquisition | New York | Remote
$280K - $310K *
Join a dynamic team as you drive new business growth through consultative sales. Leverage your technical expertise to nurture relationships and close deals, while managing forecasts and customer data...
Yesterday
$88K - $110K *
Join a team that's dedicated to enhancing healthcare professional engagements through effective coordination and support. This role involves managing peer-to-peer education programs and ensuring compl...
Yesterday
$95K - $115K *
Champion women's health by providing expert midwifery care in a collaborative, supportive environment. Enjoy a balanced work-life with a four-day week and mentorship opportunities while delivering at...
Yesterday
NERC Compliance Specialist [Remote]
$107K - $178K *
Champion compliance excellence by ensuring adherence to NERC standards, guiding operational risk management, and supporting audit preparations. Collaborate with teams to enhance compliance programs an...
Yesterday
Insights Lead, Brand & Consumer Analytics
$122K - $292K *
Empower your career by leading advanced analytics to transform data into actionable insights. Collaborate with cross-functional teams to drive strategic decisions and enhance brand and consumer initia...
Yesterday
$80K - $120K *
Contribute to customer success by developing technical expertise across platforms, integrations, and operational processes. Collaborate with teams to resolve issues and enhance solutions, while gainin...
Yesterday
$120K - $145K *
Join a dynamic team to design and optimize data pipelines, ensuring quality and security for analytics and AI capabilities. Collaborate with cross-functional teams to deliver innovative data solutions...
Reposted yesterday
Technical Program Manager, Data Center Operations
$120K - $145K *
Engage in comprehensive program management for data center operations, ensuring seamless transitions from construction to live operations. Shape maintainability, drive incident improvements, and enhan...
Reposted yesterday
Sr Advanced Mechanical Engineer
$149K - $166K *
Lead the charge in advancing cutting-edge mechanical engineering solutions for high-performance electronics in space systems. Collaborate with cross-functional teams to deliver innovative designs that...
Reposted yesterday
Nurse Practitioner Palliative Care
$95K - $115K *
Transform patient care by delivering advanced palliative services in home settings. Collaborate with an interdisciplinary team to enhance quality of life for patients facing complex medical challenges...
Yesterday
Nurse Practitioner Palliative Care
$95K - $115K *
Empower patients by delivering advanced palliative care in their homes, collaborating with an interdisciplinary team to enhance quality of life while managing complex medical needs and guiding familie...
Yesterday
Clinic Board Certified Behavior Analyst (BCBA)
$85K - $105K *
Unlock potential by leading clinical care as a BCBA, developing RBTs, and partnering with families to deliver impactful ABA services. Join a supportive team focused on quality and continuous improveme...
Yesterday
Board Certified Behavior Analyst (BCBA)
$85K - $105K *
Champion clinical excellence as a BCBA, leading care for clients, mentoring RBTs, and collaborating with families. Drive impactful change while advancing your career in a supportive environment focuse...
Yesterday
Board Certified Behavior Analyst (BCBA)
$85K - $105K *
Empower clinical excellence by leading ABA services, developing RBTs, and collaborating with families. Drive impactful treatment plans and foster a culture of quality care within a supportive team env...
Yesterday
Clinic Board Certified Behavior Analyst (BCBA)
$85K - $105K *
Join our dynamic clinical team as a BCBA, leading client care, developing RBTs, and collaborating with families to make a meaningful impact in the lives of children with autism. Grow your career in a...
Yesterday
Board Certified Behavior Analyst (BCBA)
$85K - $105K *
Elevate your career with a Board Certified Behavior Analyst role, leading clinical care, developing RBTs, and partnering with families to make a meaningful impact in the lives of children with autism...
Yesterday
Clinic Board Certified Behavior Analyst (BCBA)
$85K - $105K *
Grow your career with us as you lead clinical care, develop RBTs, and partner with families to make a meaningful impact in the lives of children with autism. Join a supportive team focused on clinical...
Yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.