Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $116,335
Associate Director Commercial Strategy and Planning
$146K - $178K *
Shape the future of biopharma by leading commercial strategy engagements, guiding clients through critical launch decisions, and delivering evidence-based recommendations to drive success in a dynamic...
1 week ago
Audit Manager/Director - State and Local Government
$85K - $168K *
Unlock potential by managing relationships with clients in local and state government, driving audit processes, and mentoring teams to achieve financial planning goals and strategic initiatives...
Reposted 1 week ago
Civil Engineering Group Manager
$140K - $180K *
Join a team that's dedicated to delivering innovative civil engineering solutions. Lead design and execution of diverse projects, mentor engineers, and ensure excellence in project delivery across the...
1 week ago
Audit Manager/Director - State and Local Government
$85K - $168K *
Empower communities by leading audit engagements, building client relationships, and fostering team development in a dynamic government-focused practice, ensuring financial objectives are met while gu...
Reposted 1 week ago
$120K - $150K *
Unlock potential by driving AI deployment strategies with clients, translating business needs into actionable use cases, and ensuring successful model adoption. Collaborate closely with engineers and...
1 week ago
Civil Engineering Group Manager
$140K - $180K *
Lead a dynamic civil engineering team, driving innovative site and land development projects across the Midwest. Oversee project execution, mentor engineers, and ensure high-quality results while fost...
1 week ago
Senior Facilities Designer, Branch Real Estate
$80K - $95K *
Lead the charge in redefining branch experiences by elevating design standards and collaborating with stakeholders. Shape innovative workplace solutions that enhance both advisor and client interactio...
Reposted 1 week ago
$94K - $266K *
Lead the optimization of service delivery operations, ensuring performance excellence and profitability. Drive continuous improvement initiatives while managing resources and client relationships to m...
Reposted 1 week ago
Manager, Functional Transformation - ServiceNow HRSD
$141K - $278K *
Manage the design and implementation of ServiceNow HRSD solutions, collaborating with teams to enhance HR practices and drive transformation. Lead project workstreams, ensuring timely delivery and qua...
1 week ago
Manager, Functional Transformation - ServiceNow HRSD
$141K - $278K *
Partner with us to lead the design and implementation of ServiceNow HRSD solutions, collaborating with teams to enhance HR practices and drive transformation, ensuring effective delivery and a superio...
1 week ago
Principal Enterprise Applications SAP Financial Services Consultant
$116K - $150K *
Drive innovative SAP Finance solutions by leading consulting projects, shaping proposals, and guiding teams to deliver value for clients in the Financial Services sector. Leverage extensive experience...
1 week ago
$140K - $160K *
Shape the future of demand generation by driving impactful campaigns, collaborating with cross-functional teams, and leveraging AI to enhance marketing efficiency. This role offers a chance to innovat...
1 week ago
$235K - $354K *
Shape the future of sales leadership by driving regional strategies, managing a high-performing team, and fostering customer relationships to achieve revenue growth and operational excellence in the l...
1 week ago
$95K - $115K *
Transform clinical quality by supporting training initiatives, monitoring clinician performance, and ensuring compliance with quality standards for successful operational processes and clinician suppo...
Reposted 1 week ago
$117K - $143K *
Empower small businesses by developing AI solutions that streamline workflows. Collaborate closely with customers to identify challenges and create impactful software that enhances efficiency and driv...
1 week ago
$155K - $160K *
Shape the future of data solutions by designing scalable architectures that drive AI and analytics initiatives. Collaborate with cross-functional teams to implement innovative strategies that enhance...
1 week ago
$125K - $190K *
Accelerate progress at a leading Customer Success team, driving renewal outcomes and enhancing team effectiveness through innovative engagement strategies and AI-driven solutions for a diverse portfol...
1 week ago
$164K - $245K *
Transform vendor legal operations by leading negotiations and enhancing processes. Collaborate with cross-functional teams to streamline agreements and empower stakeholders, ensuring efficiency and sc...
1 week ago
Missouri/Kansas Water Business Development Manager
$110K - $130K *
Pioneer business development initiatives in the water sector, driving client engagement and strategic growth across multiple market sectors. Collaborate with leadership to enhance relationships, devel...
1 week ago
Senior Plumbing Engineering Designer
$118K - $147K *
Join a dynamic MEP/FP team to lead plumbing engineering projects, ensuring high-quality designs and technical guidance across various sectors. Collaborate with multidisciplinary teams while advancing...
1 week ago
Senior Plumbing Engineering Designer
$118K - $147K *
Join our dynamic MEP/FP team to lead plumbing design for diverse projects, ensuring high-quality deliverables and technical consistency while mentoring engineers and coordinating with multidisciplinar...
1 week ago
Senior Product Marketing Manager, Vertical Solutions
$150K - $200K *
Empower our growth by managing the positioning, messaging, and GTM strategy across multiple industries, ensuring impactful narratives that resonate with diverse stakeholders and drive revenue growth t...
1 week ago
Senior Technical Product Marketing Manager, AI Agent
$150K - $200K *
Drive your career by owning the go-to-market strategy for our AI Agent platform. Collaborate with cross-functional teams to create compelling narratives and enable sales, while launching innovative pr...
1 week ago
Lake City Microgrid and CHP Site Superintendent
$90K - $110K *
Transform field oversight at an industrial site by coordinating daily operations, ensuring safety, and managing subcontractor progress. Lead multi-trade teams to achieve project goals while maintainin...
1 week ago
$80K - $95K *
Drive strategic program management for enterprise accounts, overseeing complex initiatives and fostering client relationships. Collaborate cross-functionally to enhance processes, ensure client satisf...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.