Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Registered Nurse - Baylor Weekends
$75K - $113K *
Empower patient care by guiding families through the continuum, assessing needs, coordinating care, and managing outpatient services. Collaborate with a multidisciplinary team to enhance health outcom...
1 week ago
$119K - $165K *
Join our team as a Senior Recruiter, driving full-cycle recruiting for Sales, Customer Success, and Partnerships. Collaborate with leaders to enhance our hiring processes and ensure a positive candida...
1 week ago
$79K - $112K *
Lead the charge in regional sales operations, driving revenue growth and customer satisfaction through strategic decision-making and collaboration across teams. Manage contracts, enforce compliance, a...
1 week ago
$80K - $95K *
Unlock potential by enhancing sales quality through effective training, monitoring, and compliance strategies. Collaborate with teams to drive improvements in agent performance and ensure adherence to...
1 week ago
Associate Director, Scheduling- Civil Infrastructure Construction
$175K - $220K *
Join a team that's shaping infrastructure projects through expert scheduling leadership. Your strategic planning and risk management skills will optimize resource use and ensure timely delivery in a c...
Reposted 1 week ago
$90K - $110K *
Accelerate talent acquisition by partnering with leaders to build candidate pipelines, drive recruiting efforts, and ensure timely hiring across corporate functions in a dynamic, project-driven enviro...
1 week ago
Builder Developer II/III/IV (Senior Agentic Software Engineer)
$120K - $145K *
Transform enterprise software development by leveraging AI to create autonomous agents and workflows. Drive modernization of legacy systems with innovative solutions, focusing on automation and archit...
1 week ago
Mid-Level CI Analyst - Reachback
$80K - $95K *
Transform intelligence analysis by leveraging your expertise and analytical skills. Collaborate with a dynamic team to support critical missions, utilizing advanced technology and methodologies to dri...
1 week ago
Transactional Finance, Senior Associate
$101K - $137K *
Contribute to transactional finance activities across the procure-to-pay lifecycle, ensuring accurate processing of financial transactions while supporting operational workflows and maintaining data i...
1 week ago
$125K - $150K *
Shape the future of our Climate and Commercial portfolio by leading strategic development, creating impactful go-to-market strategies, and ensuring resource allocation. Drive growth and guide optimal...
Reposted 1 week ago
Director, Strategy and Special Projects
$141K - $204K *
Drive strategic growth for DSD by leveraging data, analytics, and tools to enhance operational performance and achieve expansion goals. Collaborate with leadership to support initiatives that elevate...
1 week ago
Manager, Executive Administration
$102K - $152K *
Transform executive support by leading a dynamic team of EAs, enhancing processes, and driving strategic initiatives that align with company goals while fostering a collaborative culture...
1 week ago
$136K - $214K *
Lead the charge in optimizing revenue operations by managing a dynamic team, enhancing forecasting processes, and ensuring data integrity across systems. Collaborate closely with sales leadership to d...
1 week ago
$133K - $209K *
Lead the charge in optimizing deal structures and contract management, collaborating with cross-functional teams to streamline workflows and enhance the sales process. Your analytical skills will driv...
1 week ago
Enterprise Market Development Manager
$94K - $142K *
Champion enterprise growth by identifying and advancing strategic opportunities across healthcare networks. Build relationships with key stakeholders to develop impactful business cases and partnershi...
1 week ago
Technical Program Manager, Growth
$120K - $145K *
Lead the charge in managing our growth roadmap, ensuring seamless integration across marketing, data, and engineering teams while maintaining data integrity and optimizing performance metrics for succ...
1 week ago
Staff Pharmacist, Entry Level Closed-Door | Onsite, Chesterfield
$90K - $105K *
Drive pharmacy operations by supervising technicians, ensuring accuracy in prescription fulfillment, and maintaining patient confidentiality while collaborating with healthcare providers for optimal p...
1 week ago
Director, Academic Administration & Planning
$80K - $90K *
Drive operational and financial leadership in Academic Affairs, translating institutional priorities into actionable plans. Collaborate across departments to enhance resource stewardship and support e...
1 week ago
Assistant Vice Provost, Academic Quality & Accreditation
$138K - $142K *
Drive academic excellence and compliance by leading university-wide accreditation, policy governance, and continuous improvement initiatives. Collaborate with academic leaders to enhance institutional...
1 week ago
Associate Vice President of Philanthropy
$90K *
Join a team that's dedicated to advancing philanthropic efforts through strategic relationship-building and major gift solicitation, supporting the mission of arts education and fostering a culture of...
1 week ago
Member of Technical Staff, AI Researcher (New Stealth Startup)
$250K - $400K *
Shape the future of AI by designing evaluation frameworks and feedback systems that enhance model performance. Collaborate across teams to translate research into scalable solutions, driving impactful...
1 week ago
$100K *
Drive growth in the childcare division by leading a team of specialists, enhancing client relationships, and refining operational processes to maximize program impact and scalability...
1 week ago
Product Manager - NuPoint Time Deposits & Deposit Operations
$100K - $120K *
Reimagine banking operations by managing product roadmaps for Time Deposits and related applications. Collaborate with cross-functional teams to enhance customer experiences while ensuring compliance...
1 week ago
$93K - $150K *
Drive impactful market research initiatives by leading client relationships, managing complex projects, and mentoring teams. Collaborate with stakeholders to deliver strategic insights that enhance de...
1 week ago
BUS Regional Sales Manager - Central
$180K - $220K *
Unlock growth by driving sales strategies and managing key accounts in the data center power infrastructure sector. Collaborate with partners to enhance market presence and achieve revenue objectives...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.