Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$95K - $115K *
Help us unlock potential by providing expert legal advice on complex contract claims, environmental law, and federal employment issues. Your role will involve research, analysis, and representation in...
1 week ago
$110K - $130K *
Optimize data-driven decision-making by leading a team focused on complex analysis and reporting. Drive insights that enhance operational efficiency and inform strategic initiatives across various dep...
1 week ago
Quality Assurance Regional Manager-Midwest
$100K - $120K *
Lead the charge in ensuring product quality and safety across multiple sites. Drive a culture of excellence through effective leadership, collaboration, and training, while managing a regional quality...
1 week ago
Lead Security Operations Analyst
$110K - $130K *
Engage in a dynamic role leading security operations and AI integration. Oversee real-time threat monitoring and incident response while developing automated workflows in a cutting-edge, multi-tenant...
1 week ago
Clinical Psychologist (Remote & Night Shift)
$145K - $155K *
Join a team that's dedicated to providing virtual behavioral health services to military personnel. Utilize your expertise in clinical psychology to deliver evidence-based treatments and support patie...
1 week ago
Capital Laboratory Sales Specialist
$100K - $120K *
Join a dynamic team to drive sales of innovative laboratory equipment in the Northeast. Engage with clients, deliver product demos, and exceed sales targets while fostering strong relationships and pr...
1 week ago
Structured Settlement Sales Consultant
$80K - $95K *
Engage with personal injury attorneys to build trust and drive settlement planning referrals. Leverage your expertise in financial planning and relationship management to generate new business opportu...
1 week ago
Senior Modern Workplace Engineer II
$95K - $115K *
Elevate client experiences by leading Microsoft 365 Modern Work solutions, leveraging deep technical expertise to solve complex business challenges and drive innovation in collaboration systems...
1 week ago
Commercial CRM Business Analyst- Salesforce
$110K - $130K *
Partner with us to drive commercial CRM solutions for pharma, leading requirements gathering and process design. Collaborate with stakeholders to ensure effective system implementation and user adopti...
1 week ago
$104K - $155K *
Lead the charge in customer-focused project management, ensuring effective delivery of technical solutions while coordinating with diverse stakeholders and fostering strong relationships for successfu...
Reposted 1 week ago
Azure Solution Architect - Data & AI - USA Remote
$180K - $230K *
Lead the charge in designing and delivering innovative Azure data solutions, ensuring technical excellence and client satisfaction while guiding teams through complex implementations and strategic eng...
1 week ago
Senior Analyst, ALM & Treasury
$88K - $141K *
Empower financial strategies by analyzing interest rate and liquidity risks. Collaborate with stakeholders to enhance capital planning and reporting processes while ensuring compliance with regulation...
1 week ago
Director of Channel Partnership Development
$125K - $140K *
Engage with Private Equity firms to develop strategic partnerships, promoting supply chain services and driving revenue growth through effective channel management and collaboration with stakeholders...
1 week ago
Senior Mechanical Engineer | Kansas City, MO
$95K - $115K *
Transform mechanical design by leading HVAC, plumbing, and fire protection projects. Collaborate with clients and teams to deliver innovative, energy-efficient solutions while mentoring staff and ensu...
1 week ago
$93K - $150K *
Optimize infrastructure and CI/CD pipelines to empower engineering teams in delivering AI-powered products efficiently. Collaborate closely with product and data engineers, leading projects from incep...
1 week ago
Remote Sr. Controller - GovCon
$110K - $130K *
Champion financial excellence by leading a dynamic team, ensuring compliance, and delivering strategic insights to clients. Drive operational efficiency and foster a collaborative environment while ma...
1 week ago
$250K *
Grow your career with a strategic role focused on developing long-term partnerships with key industrial customers, enhancing relationships across multiple service lines, and driving revenue growth thr...
1 week ago
$95K - $115K *
Unlock your potential as a Program Manager, leading federal service contracts and driving operational excellence. Collaborate with teams to ensure quality delivery, financial performance, and customer...
1 week ago
Staff Product Security Engineer
$205K - $231K *
Drive your career with impactful security initiatives that enhance product safety and foster responsible AI development. Collaborate across teams to elevate security practices and implement robust gua...
1 week ago
$75K - $90K *
Champion efficient trading processes while managing SMA and UMA trades. Collaborate with clients and sponsors to execute model changes and ensure seamless trade operations. Leverage your analytical sk...
1 week ago
Principal Product Security Researcher
$201K - $226K *
Shape the future of product security by leading research initiatives, identifying emerging threats, and collaborating with cross-functional teams to enhance security strategies and drive impactful cha...
1 week ago
Senior Proposal & Pursuit Manager
$105K - $130K *
Lead the proposal development process, enhancing strategies and systems to elevate submissions. Collaborate with executives and technical experts to create compelling, client-focused proposals that sh...
1 week ago
$98K - $144K *
Transform sales strategy by leveraging advanced analytics and predictive modeling. Collaborate cross-functionally to uncover growth opportunities and optimize performance, influencing executive initia...
1 week ago
Team Lead- AI Enablement (Research)
$100K - $125K *
Champion innovation by integrating AI tools into workflows, enhancing research and consulting capabilities. Collaborate across teams to develop AI products, drive adoption, and foster a culture of con...
1 week ago
$130K - $160K *
Drive AI-native sales by building C-suite relationships and closing enterprise deals. Collaborate with account owners to identify opportunities and educate prospects on financial orchestration's value...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.