Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$120K - $125K *

Lead the charge in mobilizing significant carbon transactions across Latin America, managing multi-stakeholder relationships and driving strategic initiatives to support forest protection programs und...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Engage in advanced AC interference modeling and design mitigation systems to enhance pipeline safety. Collaborate with clients and teams to ensure compliance with industry standards while delivering e...

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$93K - $129K *

Shape your career as an Electrical Engineer by developing permit drawings for diverse projects. Collaborate with teams to provide quality designs, ensuring compliance and efficiency while engaging in...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$85K - $95K *

Transform data into actionable insights by developing predictive models and automating workflows. Collaborate in a dynamic environment to enhance decision-making and operational efficiency using advan...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $145K *

Lead the charge in managing strategic accounts, driving customer success through effective deployment and continuous improvement of our Concierge product. Collaborate with executives to uncover expans...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by leading customer deployments and driving growth through innovative solutions. Collaborate with teams to enhance product performance and teach clients to optimize their use of Conci...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$142K - $213K *

Join us to lead the proposal lifecycle for federal opportunities, collaborating with cross-functional teams to create compelling submissions that enhance win probability and support mission-driven out...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$115K - $158K *

Champion innovative MR equipment implementations, ensuring timely, high-quality installations. Collaborate with cross-functional teams to enhance project management and drive operational excellence in...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$132K - $181K *

Join our team to manage and optimize customer service projects, ensuring timely and quality service delivery. Leverage your expertise to strengthen internal partnerships and drive a positive customer...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Grow your career with a strategic role focused on managing and expanding key B2B accounts. Drive customer satisfaction and retention through consultative program management, while collaborating with c...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$90K - $110K *

Advance your career by leveraging your MicroPact Versa expertise in a remote role focused on configuring regulatory COTS solutions for commercial and government sectors. Collaborate with teams in an a...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$190K - $220K *

Drive exceptional service delivery and operational excellence as you lead a high-performing facilities management team across multiple locations, focusing on customer satisfaction and financial perfor...

St. Louis, MORemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$76K - $107K *

Empower your career as you collaborate with engineers and architects to develop innovative acoustical designs, perform analyses, and support project deliverables in a dynamic, multidisciplinary enviro...

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$140K - $223K *

Unlock potential by bridging clinical practice with AI innovation. Collaborate with clinicians and engineers to enhance workflows and patient care through AI-driven imaging solutions in a hospital set...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Elevate client success by crafting and optimizing innovative commerce media strategies. Leverage data-driven insights to enhance campaign performance across platforms, ensuring measurable growth and c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$110K - $130K *

Champion brand strategy for a diverse portfolio of university partners. Lead a team to develop positioning, messaging, and creative briefs, ensuring alignment across marketing functions while leveragi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Champion private philanthropic support by cultivating major donor relationships, securing gifts of $25,000+, and enhancing university athletics. Collaborate with diverse stakeholders to expand the don...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Transform donor engagement by managing major gift prospects, cultivating relationships, and implementing strategic fundraising initiatives. Collaborate with campus units to enhance the philanthropic r...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Unlock potential by leading the development of scalable BI solutions, collaborating with cross-functional teams to establish standards and governance, while driving analytics excellence across the org...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$141K - $234K *

Lead the charge in healthcare performance improvement by overseeing project delivery, managing client relationships, and mentoring a team of Advisory consultants to ensure successful, high-quality out...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$202K - $250K *

Elevate the Personal Care department by driving strategic billing and claims initiatives, optimizing processes for accuracy and compliance, and leading a high-performing team to achieve operational ex...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$125K - $150K *

Manage strategic tax initiatives, oversee client relationships, and lead a team of tax professionals. Drive innovative tax strategies, ensure compliance, and enhance business development efforts to el...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$110K - $150K *

Unlock potential by leading claims adjudication logic to enhance accuracy and efficiency. Drive strategic improvements, collaborate across teams, and ensure compliance while optimizing operations in a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $107K *

Drive product strategy and enhancements by collaborating across teams to optimize performance, efficiency, and customer satisfaction. Leverage data insights to evolve offerings and ensure alignment wi...

Bridgeton, MORemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$88K - $163K *

Help us optimize Workday integrations by configuring, testing, and delivering high-quality solutions across multiple projects. Collaborate with clients and teams to enhance processes and deepen your e...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.