Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$80K - $95K *
Drive growth by acquiring new customers for our innovative SaaS solutions. Leverage your sales expertise to engage decision-makers, understand their needs, and promote our Amplify Platform, focusing o...
1 week ago
ServiceNow Infrastructure Engineer
$95K - $115K *
Take ownership of the ServiceNow on-premise infrastructure, ensuring optimal deployment, maintenance, and security of the platform. Collaborate with teams to enhance system performance and support inn...
1 week ago
Account Executive, Midwest ECM
$80K - $95K *
Unlock potential by driving growth in our Enterprise Content Management business. Engage with diverse stakeholders, navigate complex sales cycles, and expand client relationships across the Midwest wh...
1 week ago
$120K - $145K *
Champion innovative solutions by leading cross-functional teams to tackle complex engineering challenges, mentoring peers, and driving technical excellence across projects of significant scope and sca...
1 week ago
Sr. Sales Account Executive - West
$135K - $245K *
Unlock your potential as a Senior Sales Account Executive, driving strategic sales initiatives across diverse industries. Engage with C-level executives, manage complex sales cycles, and leverage inno...
1 week ago
Surgical Sales Representative (Remote - St. Louis)
$90K - $110K *
Champion revenue growth for the breast device portfolio by executing strategic sales initiatives, building relationships with key stakeholders, and providing expert consultation in surgical environmen...
1 week ago
Surgical Sales Representative (Remote - St. Louis)
$80K - $95K *
Elevate your career by driving revenue for a breast device portfolio. This role involves strategic planning, customer engagement, and case coverage in surgical environments, requiring expertise in pla...
1 week ago
Manager, Digital Marketing Operations
$86K - $110K *
Take ownership of digital marketing operations, managing CRM campaigns and creative processes. Collaborate across teams to enhance performance, streamline workflows, and leverage AI for improved resul...
1 week ago
$175K - $200K *
Transform compliance within a dynamic enterprise by designing and overseeing an effective Ethics and Compliance Program that aligns with regulations and promotes enterprise growth. Drive culture and a...
Reposted 1 week ago
$140K - $160K *
Unlock potential by driving the evolution of AWS environments and CI/CD pipelines, enhancing observability and security, while collaborating with engineers to optimize platform reliability and perform...
1 week ago
Senior Manager - Regulatory Affairs
$85K - $120K *
Lead the charge in regulatory affairs by providing strategic guidance, ensuring compliance, and fostering collaboration across institutions. Drive initiatives from research to implementation while men...
1 week ago
Field Sales Credit Manager - MI Telecommuter
$90K - $135K *
Empower a dynamic sales team to drive financial product growth, enhance client relationships, and achieve sales targets through strategic initiatives and market analysis while ensuring compliance and...
1 week ago
$95K - $115K *
Join our dynamic customer success team to enhance client engagement and drive product adoption. You'll be the key liaison for customers, ensuring they maximize value from our solutions while advocatin...
1 week ago
Senior Manager IGA Engineering (Sailpoint ISC)- Remote
$130K - $155K *
Drive the technical strategy for identity governance services, leading a team to enhance identity security across the organization. Collaborate with cross-functional teams to implement SailPoint solut...
1 week ago
$120K - $145K *
Join us to lead the delivery of network infrastructure, overseeing contractors and ensuring high-quality installations. You'll manage site execution, coordinate with teams, and drive project success t...
1 week ago
$120K - $150K *
Innovate within a cutting-edge DataOps environment, ensuring the reliability and scalability of a Databricks-native data platform on Azure. Leverage AI for observability and pipeline management while...
1 week ago
$95K - $115K *
Engage with key strategic customers to foster relationships and drive growth. Collaborate across teams to deliver tailored solutions, ensuring customer satisfaction and long-term partnerships while ac...
1 week ago
Product Manager, Ignite Member Operations
$125K - $141K *
Lead the product direction for membership operations, balancing customer needs and enterprise requirements. Collaborate with teams to enhance workflows, improve operational outcomes, and ensure a seam...
1 week ago
$97K - $130K *
Optimize business processes and technology solutions by collaborating with stakeholders to gather requirements, drive implementation, and enhance user experience, ensuring alignment with organizationa...
1 week ago
$90K - $135K *
Champion a culture of safety by leading initiatives, providing expert guidance, and ensuring compliance with safety standards across multiple projects. Collaborate with management to foster a safe wor...
1 week ago
$80K - $95K *
Analyze and oversee corrosion inspections and repairs, ensuring compliance with regulations. Maintain records, perform system installations, and provide technical support while driving mitigation acti...
1 week ago
Principal AI Transformation Consultant
$136K - $160K *
Drive transformation by partnering with architecture and engineering firms to enhance workflows through AI-enabled solutions. Collaborate with stakeholders to redefine processes, ensuring operational...
1 week ago
Clinical Study Physician - Oncology - FSP
$160K - $200K *
Lead the charge in medical oversight for clinical trials, ensuring high standards and executing timelines. Collaborate with cross-functional teams to enhance trial protocols and contribute to impactfu...
Reposted 1 week ago
Cardiology Hospitalist | Weekday Schedule + Minimal Call | St. Louis
$250K - $300K *
Elevate inpatient cardiac care by joining a dedicated team focused on consultative cardiology. Enjoy a supportive environment with limited weekend call, advanced diagnostics, and a collaborative appro...
1 week ago
Data Center Infrastructure Delivery Manager , DCC Communities
$107K - $188K *
Lead the charge in optimizing data center operations while managing a skilled team focused on installing and delivering essential network infrastructure. Drive compliance and enhance performance throu...
Reposted 1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.