Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Accountant, Financial Reporting
$78K - $130K *
Drive financial accuracy and transparency by managing external reporting, technical accounting, and equity accounting. Collaborate with cross-functional teams to ensure compliance with U.S. GAAP and S...
1 week ago
Senior Tax Associate - UHNW (Northeast)
$99K - $110K *
Lead the preparation and delivery of tax returns for ultra-high-net-worth clients. Enjoy a supportive environment with no billable hours, focusing on client service and tax compliance while benefiting...
1 week ago
$240K - $330K *
Transform security operations by leading a dynamic Product Security team. Drive risk-based strategies, empower engineering teams, and enhance security posture through automation and collaboration. Sha...
Reposted 1 week ago
$110K - $130K *
Contribute to impactful consulting services in government pricing, leveraging your expertise to guide clients through compliance, data analysis, and strategic initiatives while leading a collaborative...
1 week ago
Senior AI Software Engineer (RD271)
$130K - $155K *
Drive innovation by developing AI-driven software solutions that enhance secure application delivery. Collaborate with cross-functional teams to tackle complex challenges and shape the future of softw...
1 week ago
Associate Territory Manager - St. Louis
$70K - $95K *
Accelerate progress at the intersection of sales and clinical support, driving account growth and customer engagement. Collaborate with Territory Managers to enhance utilization of medical devices and...
1 week ago
Associate Territory Manager - St. Louis
$70K - $95K *
Optimize sales and support efforts in a field-based role, collaborating with Territory Managers to enhance account management and drive growth. Engage with healthcare professionals to promote product...
1 week ago
$135K - $160K *
Champion the future of K12 education by leading a dynamic Customer Success team. Drive strategic initiatives, foster executive relationships, and ensure customer satisfaction across the NORAM K12 land...
Reposted 1 week ago
Senior Professional Services Engineer - PubSec - US Only
$136K - $230K *
Elevate customer success by delivering Professional Services engagements, including installation, migration, and training, while collaborating with project managers to enhance delivery consistency and...
1 week ago
Director of Market Development & Referral Strategy
$110K - $130K *
Lead the charge in developing referral growth and market strategies across multiple states. Drive sustainable growth by optimizing processes, leveraging CRM systems, and building high-performing teams...
1 week ago
Senior Application Security Engineer
$177K - $265K *
Lead security initiatives to enhance application security across the SDLC. Collaborate with cross-functional teams to embed security practices, conduct threat modeling, and mentor engineers, ensuring...
1 week ago
$110K - $130K *
Transform fire protection engineering for large-scale data centers by establishing design criteria, reviewing complex systems, and ensuring compliance from design through operational handover, while c...
1 week ago
Senior Enterprise Platforms Product Manager
$102K - $190K *
Transform product strategy and delivery for Payment Integrity platforms, driving initiatives from planning to execution. Collaborate across teams to enhance efficiency and leverage AI tools for improv...
1 week ago
$80K - $95K *
Deliver exceptional client strategies and manage Meta campaigns to enhance performance and retention. Own client relationships, lead discussions, and optimize advertising efforts to drive results and...
1 week ago
$95K - $115K *
Shape the future of financial operations by owning and modernizing financial systems, automating processes, and collaborating with engineering to streamline integrations for enhanced efficiency and re...
Reposted 1 week ago
FEMA PA Program Delivery Manager
$70K - $150K *
Join a team that's dedicated to supporting disaster recovery efforts through federal funding programs. Collaborate with local governments and nonprofits to ensure compliance and effective project form...
Reposted 1 week ago
$70K - $110K *
Join a team that's dedicated to supporting disaster recovery efforts. Collaborate with leadership and clients to navigate complex recovery operations, ensuring effective management of multi-billion do...
Reposted 1 week ago
$100K - $120K *
Discover and attract top talent for clients by employing innovative sourcing techniques. Collaborate closely with stakeholders to enhance recruitment practices and immerse yourself in client cultures...
1 week ago
$80K - $95K *
Take ownership of a multi-million dollar Amazon catalog, driving strategy and growth. Collaborate with a high-performing team to enhance brand presence, optimize listings, and elevate profitability th...
1 week ago
$92K - $138K *
Transform operational effectiveness by leading implementation initiatives across regions. Collaborate with teams to ensure successful activation, training, and adoption of non-medical changes, enhanci...
1 week ago
Staff Decision Scientist, Advanced Analytics
$130K - $242K *
Lead advanced analytics initiatives to enhance MAU insights, driving growth through experimentation and causal inference. Collaborate across teams to establish standards and leverage AI for scalable s...
1 week ago
Senior Director, Compliance & Platform
$214K - $268K *
Shape the strategy and outcomes for compliance and platform products, leading a team of product managers and domain experts. Drive innovation and customer engagement while ensuring enterprise-scale de...
1 week ago
$110K - $120K *
Empower your career by leading business analysis and configuration efforts. Collaborate with stakeholders to translate objectives into actionable requirements, ensuring successful project delivery and...
1 week ago
$120K - $145K *
Lead the Sales Enablement team to drive impactful initiatives, collaborating with cross-functional leaders to enhance sales effectiveness in a fast-paced AI environment. Balance priorities and deliver...
1 week ago
Vice President, Global Channel Sales
$290K - $342K *
Drive global partner and channel strategy, enhancing relationships and expanding market reach. Lead a high-performing team to innovate and execute programs that boost cross-sell opportunities and esta...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.