Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$95K - $125K *
Transform client relations through innovative sales strategies while achieving consistent targets in a dynamic market. Drive growth by effectively managing existing partnerships and exploring new oppo...
Reposted 1 week ago
Sr. Consultant / Project Manager
$95K - $115K *
Empower client success by leading software implementation projects, fostering relationships, and driving innovation. Manage timelines and deliverables while ensuring satisfaction through expert guidan...
1 week ago
Salesforce Solutions Architect (Financial Services Cloud) - USA (Remote)
$120K - $145K *
Shape innovative Salesforce solutions for financial services by leading design, architecture, and delivery of complex projects. Collaborate with clients and teams to ensure successful implementations...
1 week ago
Lifecycle Acquisition Analyst, Mid
$78K - $90K *
Unlock potential by providing expert lifecycle acquisition support for NGA programs, developing key documentation, and ensuring timely procurement actions through collaboration with technical and fina...
1 week ago
Colleague Finance Functional Consultant - Remote (anywhere in US)
$90K - $110K *
Partner with us to enhance financial systems in higher education. Leverage your Colleague Finance expertise to optimize processes, troubleshoot issues, and support institutions in their technology tra...
1 week ago
Senior/Principal Software Engineer
$150K - $180K *
Develop and optimize high-performance software systems using Rust, focusing on Linux environments and distributed applications. Collaborate on architecture and enhance software quality through modern...
1 week ago
Solutions Engineer | PST or EST US | Remote
$182K - $226K *
Unlock potential by joining a dynamic team that drives customer success through technical expertise and innovative solutions, enhancing product engagement and collaboration in a fast-paced startup env...
1 week ago
Director, Application & Technical Service
$135K - $160K *
Drive a unified technical organization to enhance customer support from application discovery to project conversion, focusing on team development, technical selling, and improving customer experiences...
1 week ago
$125K - $172K *
Transform healthcare delivery by managing CDI operations, liaising with vendors, ensuring quality, and fostering staff development. Join a collaborative team to enhance patient care through innovative...
Reposted 1 week ago
$85K - $100K *
Unlock potential by providing essential physical therapy services in home settings, enhancing patient mobility and health. Collaborate with a supportive team to ensure quality care and promote overall...
1 week ago
$135K - $160K *
Lead the charge in offensive security research, tackling software supply chain vulnerabilities and zero-day threats. Collaborate with teams to innovate security capabilities and publish impactful find...
1 week ago
Associate Director, Biostatistics
$173K - $209K *
Transform your career by leading biostatistical strategies for clinical trials, driving innovative therapies from design to regulatory submission. Collaborate with multidisciplinary teams to ensure da...
1 week ago
$130K - $150K *
Join a dynamic team to design and develop innovative mobile solutions across Android and iOS. Take ownership of projects, collaborate with peers, and contribute to the broader tech stack while enhanci...
1 week ago
Director, Pricing Strategy and Monetization ( Remote)
$233K - $330K *
Elevate your career by leading innovative pricing strategies for cutting-edge AI solutions. Collaborate across teams to optimize monetization models and drive value in a dynamic market, ensuring Cisco...
1 week ago
$95K - $115K *
Elevate your career by leading engineering and maintenance operations, ensuring safety and efficiency in a high-pressure production environment while managing budgets, projects, and a dedicated team t...
1 week ago
$92K - $120K *
Join a team that's dedicated to enhancing sales performance through innovative training. You'll design and deliver engaging learning experiences, collaborate with sales leaders, and leverage AI tools...
1 week ago
Global Flagship Accounts Manager
$216K - $361K *
Drive customer retention and growth by managing strategic accounts, collaborating cross-functionally to enhance customer experiences, and achieving revenue targets through effective account planning a...
1 week ago
Director of Financial Reporting
$125K - $150K *
Drive compliance and accuracy in financial reporting, overseeing SEC filings and governance. Collaborate with leadership to enhance transparency and support strategic initiatives while ensuring adhere...
1 week ago
Murex Environment and Configuration Manager
$120K - $145K *
Take ownership of the Murex environment lifecycle, ensuring stability and performance. Lead strategic improvements, mentor team members, and manage stakeholder relationships while driving innovation a...
Reposted 1 week ago
$292K - $344K *
Champion the growth of agency sales by leading a dynamic team, driving revenue, and fostering strong client relationships. Collaborate with executives to shape strategies and ensure Fetch's value reso...
1 week ago
Senior Professional Services Engineer - PubSec
$138K - $230K *
Join a dynamic team to deliver professional services, guiding public sector clients in adopting GitLab through installations, migrations, and training. Balance technical expertise with project managem...
1 week ago
$124K - $161K *
Empower the future of medical device manufacturing by leading process engineering initiatives, driving continuous improvement, and ensuring compliance while collaborating with cross-functional teams t...
1 week ago
Regional Clinical Trial Management Senior Associate
$83K - $113K *
Drive regional clinical study delivery by supporting management and execution of trials, ensuring quality standards and timelines are met. Collaborate with stakeholders and contribute to operational e...
1 week ago
Wealth Management Marketing Manager
$80K - $95K *
Shape client success by managing campaigns and relationships. Drive performance through strategic insights, optimize Meta advertising, and ensure client satisfaction while tackling challenges proactiv...
1 week ago
Senior Copywriter, Promotional Medical Writing
$80K - $100K *
Advance impactful medical communications by crafting precise, engaging content. Collaborate with cross-functional teams to ensure accuracy and alignment with client objectives while mentoring junior s...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.