Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Rust Senior Software Engineer - Bare Metal as a Service & Datacenter Networking
$135K - $160K *
Drive your career forward by developing cutting-edge control planes for AI infrastructure. Collaborate with a dynamic team to enhance cloud-native orchestration platforms, leveraging your expertise in...
1 week ago
Director Technology, Product & Engineering - SRC Logistics Inc.
$125K - $150K *
Champion the development of a customer-focused software product, leading engineering teams and driving product strategy to enhance RLMS. Oversee technology investments, infrastructure, and security to...
1 week ago
Salesforce Certified Developer - Public Sector/Govt Cloud
$130K - $165K *
Elevate public sector solutions by designing and delivering scalable Salesforce applications. Collaborate with cross-functional teams to enhance operational efficiency and modernize processes, ensurin...
1 week ago
$110K - $130K *
Join a dynamic team to manage tax compliance and planning across multiple entities. Collaborate with Finance, Legal, and Operations to enhance tax processes and support strategic projects in a growing...
1 week ago
Circulating Nurse Keene Street Medical Center
$71K - $106K *
Engage in direct patient care by assessing, planning, and implementing nursing strategies while collaborating with a multidisciplinary team to enhance patient satisfaction and outcomes...
1 week ago
Sr. Collections Strategy Manager
$145K - $175K *
Optimize strategies by leading multi-channel collections initiatives, leveraging analytics and AI to enhance performance and drive payment conversions. Collaborate cross-functionally to design and imp...
1 week ago
Adobe target Architect - MarTech
$110K - $130K *
Transform the future of digital engagement by leading Adobe Target implementations. Collaborate across teams to develop personalized strategies that enhance user experiences and drive measurable busin...
1 week ago
$125K - $150K *
Transform data integration in modern data centers by leading a team to design and implement edge collectors, ensuring seamless connectivity and efficient onboarding across multiple sites while collabo...
1 week ago
Senior Sales Associate - CB Infrastructure
$195K - $230K *
Join a team that's redefining partnership development in the fintech space. You'll drive new opportunities with PSPs and banks, managing complex deals and collaborating cross-functionally to enhance C...
1 week ago
$216K - $361K *
Elevate your career by driving sales growth in enterprise software across retail, energy management, and telecommunications. Collaborate with top clients to achieve strategic goals and expand market p...
1 week ago
$210K - $250K *
Transform patient care by leading a comprehensive cardiology program, managing clinical, administrative, and research components while ensuring high-quality treatment for cardiac diseases in a collabo...
1 week ago
Senior AI Software Engineer (RD271)
$148K - $201K *
Join us to shape the future of secure software delivery by developing AI-driven workflows and orchestrating complex systems. Collaborate with cross-functional teams to create intuitive solutions that...
1 week ago
$91K - $122K *
Empower and lead a high-performing sales team to exceed targets, fostering strategic relationships and guiding consultative sales strategies that highlight key market differentiators for sustained gro...
Reposted 1 week ago
$120K - $185K *
Transform the future of engineering design by leading diverse teams to deliver high-quality electrical engineering solutions. Drive project success through strategic oversight, mentoring, and adherenc...
1 week ago
$135K - $145K *
Drive innovative software solutions by developing robust, cloud-native systems that enhance provider data management capabilities and meet the evolving needs of clients in a dynamic, collaborative env...
Reposted 1 week ago
Systems & Integration Support Analyst
$120K - $140K *
Unlock potential by joining a dynamic team that enhances naval supply systems through application engineering, integration, and support. Collaborate with partners to refine requirements and ensure sys...
1 week ago
Strategic Project Lead - Speech & Audio AI (United States)
$100K - $120K *
Join us to lead strategic projects in speech and audio, driving high-quality data programs for AI. You'll manage complex workflows, enhance client communication, and ensure quality standards in a rapi...
1 week ago
Manager, Software Engineering (Resilience Engineering)
$204K - $290K *
Manage the Resilience Engineering team to enhance system reliability through production load testing and chaos engineering while fostering a proactive safety culture across engineering practices...
Reposted 1 week ago
$80K - $95K *
Join a team that's redefining operational excellence in healthcare. This role drives performance and compliance across call center operations, enhancing efficiency and quality through strategic planni...
1 week ago
$85K - $121K *
Shape your career by leading a dynamic team in Operations, ensuring client satisfaction and effective implementation of Web Pay Products. Drive success through coaching and problem-solving in a fully...
1 week ago
$160K - $390K *
Join a team that's dedicated to delivering high-quality dental care while enhancing your skills through mentorship and advanced technology in a collaborative environment focused on patient outcomes...
1 week ago
Director of Nursing | DON | RN
$80K - $95K *
Join us in providing exceptional nursing leadership and care management! You will oversee nursing services, ensuring quality standards, and lead nursing staff while managing center operations in the a...
Reposted 1 week ago
$110K - $130K *
Join a team that's dedicated to enhancing client relationships and driving success. Oversee client performance, mentor staff, and ensure compliance while collaborating with various departments to deli...
Reposted 1 week ago
Principal Technology Partner Executive
$150K - $214K *
Innovate and lead strategic partnerships in the HCM and WFM sectors, driving joint solutions and aligning cross-functional teams to enhance product offerings and deliver exceptional value to customers...
1 week ago
Traveling General Superintendent - ATG
$100K - $120K *
Unlock potential by leading project coordination and trade management for advanced technology initiatives, ensuring quality and efficiency across diverse construction environments while supporting ope...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.