Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Solution Architect (P&C insurance domain)
$135K - $160K *
Lead the charge in architecting a cutting-edge Commercial Lines insurance platform, focusing on microservices and event-driven architecture. Collaborate with cross-functional teams to define and deliv...
1 week ago
Physician - Psychiatrist (Substance Use Disorders)
$180K - $220K *
Innovate psychiatric care by leading evaluations, treatments, and documentation. Collaborate with residents and nurse practitioners while ensuring compliance with regulations. Participate in on-call r...
1 week ago
$92K - $115K *
Champion client performance by managing Meta ad campaigns, optimizing strategies, and crafting compelling direct-response content to enhance engagement and retention across multiple accounts...
Reposted 1 week ago
Implementation Consultant, Audit
$100K - $120K *
Build customer relationships by delivering seamless onboarding and maximizing platform adoption, driving value realization through proactive guidance and cross-team collaboration...
Reposted 1 week ago
Manager, Technology, Data and AI Advisory, Energy & Utilities
$125K - $150K *
Transform the energy & utilities landscape by leading OT and infrastructure workstreams throughout the private equity investment lifecycle, driving diligence, integration, and value creation for criti...
1 week ago
Director, Institute for Cybersecurity - College of Business and Computing
$100K - $120K *
Transform cybersecurity education by leading strategic initiatives, fostering partnerships, and enhancing community engagement. Drive program development and research to prepare students for dynamic c...
1 week ago
$110K - $210K *
Advance your career by designing innovative Anaplan solutions that address client needs while leading Agile projects and training teams. Shape the technical vision and enhance processes for impactful...
Reposted 1 week ago
$87K - $157K *
Transform your career by joining a dynamic team to design and deploy next-generation air traffic control systems, ensuring safety and efficiency across the National Airspace System through innovative...
1 week ago
$92K - $166K *
Champion enterprise compensation programs by managing operations, analytics, and job architecture. Collaborate with HR and business leaders to ensure compliance and drive strategic initiatives in a dy...
1 week ago
$73K - $132K *
Join a team that's dedicated to innovation and excellence in various roles, from engineering to intelligence. Contribute your skills to impactful projects that enhance national security and technologi...
1 week ago
Mission Operations & Cyber Resilience Lead
$107K - $195K *
Drive mission-critical operations and cybersecurity for a federal health data exchange. Lead 24x7 platform management, incident response, and vulnerability remediation to ensure seamless service for m...
1 week ago
$92K - $166K *
Elevate team performance by facilitating agile processes, removing impediments, and ensuring alignment between stakeholders and development teams. Drive continuous improvement and deliver value throug...
1 week ago
GEO-SPI Talent Hub - Employee Referrals
$73K - $132K *
Shape the future of national security by leveraging advanced data analysis and imagery expertise. Collaborate with a dynamic team to support critical missions and drive innovation in intelligence oper...
1 week ago
$69K - $125K *
Optimize site deployment for FAA NextGen programs by leading coordination, communication, and technical support. Ensure successful installation, maintenance, and certification of systems while managin...
1 week ago
Junior Exploitation Specialist/Photogrammetrist
$59K - $106K *
Join a team that's dedicated to delivering high-quality photogrammetry support. Collaborate with senior specialists to produce remote reconnaissance packages for geodetic surveys, utilizing advanced d...
1 week ago
$123K - $137K *
Lead site management activities by overseeing installation teams, ensuring project success through effective communication, risk mitigation, and adherence to quality standards across all on-site opera...
Reposted 1 week ago
Senior Identity Governance Engineer
$134K - $201K *
Design and engineer identity governance solutions to ensure secure access across diverse environments. Collaborate with cross-functional teams to implement standards, automate workflows, and maintain...
1 week ago
$204K - $327K *
Drive innovative legal solutions as a key partner for AI and product teams, providing comprehensive guidance on regulatory challenges and product development. Collaborate cross-functionally to ensure...
1 week ago
$263K - $395K *
Transform the technical landscape by defining and delivering innovative solutions, mentoring engineers, and shaping strategic initiatives to enhance system architecture and performance across the orga...
1 week ago
Customer Success Manager, Enterprise
$92K - $139K *
Drive customer success by managing a portfolio of enterprise accounts, ensuring optimal software utilization, and fostering strong relationships to enhance client satisfaction and revenue growth...
1 week ago
Commercial Credit Analyst III - Warehouse Lending
$80K - $95K *
Evaluate and analyze the creditworthiness of commercial borrowers, preparing detailed credit analyses and recommendations to support lending decisions while collaborating with banking professionals to...
1 week ago
$137K - $155K *
Lead digital transformation initiatives to enhance vegetable seed processing operations. Drive change management, develop data solutions, and optimize digital tools for global integration, ensuring su...
1 week ago
Senior Business Insights Analyst
$110K - $131K *
Transform complex data into actionable insights, partnering with leaders to enhance strategic decision-making and drive organizational performance through advanced analytics and reporting frameworks...
1 week ago
$91K - $163K *
Transform patient care by leveraging your clinical expertise to ensure safe, effective medication management. Collaborate with healthcare teams to optimize drug therapy and enhance patient outcomes in...
1 week ago
Strategic Account Executive, West
$200K - $240K *
Lead the charge in enterprise sales by acquiring new logos and building strategic relationships. Drive growth in a competitive market, leveraging your expertise to navigate complex sales cycles and de...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.