Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$95K - $133K *
Join a team that's building and leading a high-performing Business Development group. Drive prospecting strategies, enhance team performance, and collaborate with Sales and Marketing to accelerate pip...
1 week ago
$80K - $95K *
Lead a dynamic team of travel therapy recruiters while driving personal production. Champion recruitment strategies, enhance team performance, and ensure alignment with client demands to achieve booki...
1 week ago
Supply Planning Quality Manager
$88K - $105K *
Pioneer continuous improvement in supply planning operations, driving efficiency and governance. Leverage expertise in inventory optimization and Infor ERP systems to enhance processes and support ope...
1 week ago
Hardware Security Consultant / Penetration Tester
$80K - $150K *
Unlock potential by driving hardware security assessments, improving client security postures, and delivering actionable insights. Collaborate with teams and engage directly with clients while enhanci...
Reposted 1 week ago
$100K - $120K *
Optimize integration processes by bridging technical gaps between systems. Collaborate with campus IT to ensure seamless data flows, troubleshoot issues, and enhance integration reliability for succes...
1 week ago
Senior Software Engineer, Infrastructure Engineering
$190K - $267K *
Champion innovation by leading cross-functional teams to design and deliver scalable, high-performance infrastructure solutions that enhance reliability and efficiency across diverse applications and...
1 week ago
$130K - $160K *
Join a team that's building from the ground up, shaping the engineering foundation and culture while collaborating closely with leadership to define and deliver innovative products...
1 week ago
$126K - $137K *
Champion innovative software solutions by developing and optimizing full-stack applications in the CAD/CAE domain, leveraging Java, Angular, and cloud technologies to enhance user experience and perfo...
1 week ago
Field CISO - Client Advisory | Remote, Central Region
$150K - $180K *
Advance client security through strategic advisory and tailored solutions, leveraging deep cybersecurity expertise to mitigate risks and drive positive change. Collaborate with sales teams, maintainin...
Reposted 1 week ago
Field CISO - Client Advisory | Remote, Central Region
$150K - $180K *
Unlock potential by serving as a strategic security advisor, guiding clients through their cybersecurity challenges with tailored solutions while collaborating with sales teams and maintaining industr...
Reposted 1 week ago
Field CISO - Client Advisory | Remote, Central Region
$150K - $180K *
Strategize comprehensive cybersecurity solutions, influencing client security outcomes. Leverage technical expertise to bridge client needs and offering development, fostering robust relationships and...
Reposted 1 week ago
$250K - $500K+*
Optimize and innovate software kernels for hardware integration, collaborating with ML Research and Hardware Engineering teams to enhance performance and efficiency in cutting-edge technology applicat...
1 week ago
Senior Software Engineer, Platform Infrastructure
$165K - $225K *
Elevate infrastructure capabilities by designing and implementing a unified platform that integrates bare-metal servers, storage, and networking for large-scale computation and AI workloads, ensuring...
1 week ago
Business Development and Marketing Specialist - Litigation | Labor & Employment
$90K - $120K *
Support and enhance business development initiatives for Litigation and Labor & Employment Departments. Collaborate with senior managers and attorneys to drive client engagement, execute marketing str...
1 week ago
$100K - $120K *
Champion growth by owning the full sales cycle, educating clients, and driving custom part sourcing for hardware companies. Collaborate with a remote team to deliver exceptional service and build last...
1 week ago
$170K - $200K *
Transform customer experiences by providing technical expertise and solutions. Collaborate with sales and engineering teams to deliver impactful product demonstrations and address technical challenges...
1 week ago
Clinical Trial Manager/Senior Clinical Trial Manager
$110K - $200K *
Join a team that's dedicated to advancing clinical research by leading operational aspects of trials, ensuring compliance with protocols and regulations, and fostering collaboration among stakeholders...
1 week ago
Sr Manager, Payroll Connection & Integration Support
$135K - $145K *
Lead the charge in optimizing payroll integration operations, managing teams, and driving strategic alignment across functions. Elevate customer experience through data-driven insights and innovative...
1 week ago
Sr. Software Engineer - Stacklok Enterprise
$189K - $231K *
Innovate and shape the future of AI platforms as a Senior Engineer, designing and building critical subsystems for enterprise Kubernetes environments. Collaborate with customers and mentor engineers t...
1 week ago
$96K - $120K *
Empower businesses by providing tailored banking solutions, driving client engagement, and achieving sales goals. Collaborate with branch teams to enhance service offerings and foster strong relations...
1 week ago
Director, Market Access - Commercial Coverage & Reimbursement
$187K - $281K *
Redefine market access strategies by leading payer engagement to enhance patient access to genomic testing. Collaborate cross-functionally to drive favorable coverage and reimbursement policies, ensur...
1 week ago
Senior Field Engineer, Data Center Design and Engineering
$320K - $405K *
Transform the future of data center engineering by resolving on-site technical issues, collaborating with contractors, and ensuring project success through effective problem-solving and communication...
1 week ago
$130K - $160K *
Create impactful solutions as a Senior Product Engineer, owning projects from concept to delivery. Collaborate with a dynamic team, leveraging AI tools to enhance development while mentoring peers and...
1 week ago
Shop Supervisor - Kansas City, MO
$80K - $85K *
Lead the charge in managing a skilled team of mechanics and technicians, ensuring high-quality maintenance and repair of heavy equipment while fostering a safe and efficient work environment...
Reposted 1 week ago
Nurse Practitioner (Maternal Fetal Medicine) - Ob/Gyn
$97K - $174K *
Accelerate patient care as a Nurse Practitioner in Maternal Fetal Medicine, managing complex pregnancies and collaborating with specialists to ensure comprehensive support for mothers and babies in an...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.