Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$80K - $90K *
Elevate your career by building and maintaining a network of specialist consultants and physicians. Drive business growth and enhance clinical trial delivery through strong relationships and strategic...
1 week ago
$69K - $101K *
Manage supplier relationships and procurement processes to ensure seamless production. Collaborate with cross-functional teams to track costs, monitor delivery performance, and resolve material shorta...
1 week ago
Business Development Manager- WA/OR
$95K - $115K *
Accelerate progress at the forefront of commercial fleet sales by driving new customer acquisition and expanding market share through strategic relationship building and consultative selling in a dyna...
1 week ago
Manager, Infrastructure Governance
$125K - $178K *
Accelerate progress at the forefront of cloud security governance, leading a dynamic team to enhance compliance, drive automation, and ensure robust risk management across multi-cloud environments...
1 week ago
Self-Managed Business Development Manager- East Region
$100K - $120K *
Champion growth by driving new customer acquisition and fleet sales within your territory. Leverage consultative selling and relationship-building to secure small to medium-sized business clients, enh...
1 week ago
$150K - $180K *
Transform sales leadership by building and guiding a high-performing team to drive growth and retention in the AMER region, collaborating across departments to execute strategic initiatives and enhanc...
1 week ago
Associate Medical Director, Global Safety Physician
$184K - $253K *
Drive global pharmacovigilance efforts by managing safety data, leading clinical development strategies, and collaborating across teams to enhance product safety and efficacy throughout their lifecycl...
1 week ago
$150K - $180K *
Lead high-impact executive searches across IT services, leveraging AI tools and a robust network to identify and engage top-tier talent. Drive outcomes by advising senior leaders and ensuring successf...
1 week ago
$110K - $130K *
Unlock potential by driving enterprise sales through consultative approaches, managing complex deals with multiple stakeholders, and leveraging a proven sales methodology to achieve targets and foster...
1 week ago
SAP Sales & Distribution Order to Cash Dassian Consultant
$116K - $243K *
Unlock your potential as a functional SME in SAP S/4HANA Order-to-Cash, supporting critical operations in a classified aerospace and defense environment. Collaborate with teams to enhance procurement...
1 week ago
Regional Sales Manager - North Central US & Central Canada
$95K - $115K *
Grow your career with a strategic sales role focused on telecommunications solutions, where you'll drive revenue growth, foster customer relationships, and collaborate with teams to achieve targets wh...
Reposted 1 week ago
Regional Sales Manager - North Central US & Central Canada
$95K - $115K *
Advance your career by driving solution-based sales in telecommunications. Collaborate with customers and internal teams to deliver exceptional service and achieve revenue goals while managing a defin...
Reposted 1 week ago
Regional Sales Manager - North Central US & Central Canada
$95K - $115K *
Drive growth by leveraging telecommunications expertise in fiber and wireless solutions. Engage with distributors and end users to transform challenges into sales opportunities, while managing territo...
Reposted 1 week ago
Assistant Vice President - Captive Solutions
$165K - $200K *
Transform captive program management by driving portfolio growth, enhancing underwriting practices, and fostering strong partner relationships. Join a dynamic team to shape innovative solutions and de...
1 week ago
Security & AI Proposal Specialist
$94K - $102K *
Drive your career with a hands-on role coordinating customer security and AI assessments. Collaborate across teams to streamline processes, enhance communication, and ensure timely responses, enabling...
1 week ago
$80K - $95K *
Join a dynamic team as you lead outside sales efforts, mentoring new talent while managing client relationships. Leverage your extensive sales experience to drive growth and deliver tailored insurance...
1 week ago
Systems Engineer (Expert) Job# 934
$130K - $155K *
Lead cross-functional engineering teams to enhance geospatial intelligence solutions, ensuring timely and accurate delivery through expert systems engineering, integration, and strategic planning acro...
1 week ago
Strategic Accounts Manager, Data Centers - US Robotics West
$110K - $130K *
Join a pioneering team driving sales growth in the data center segment. You'll develop strategies, manage key accounts, and lead a virtual team to enhance customer satisfaction and deliver value in a...
1 week ago
$111K - $167K *
Join a team that's driving healthcare transformation by leading client integration initiatives. Collaborate across departments to ensure seamless transitions, operational readiness, and long-term succ...
1 week ago
$95K - $160K *
Grow your career with a dynamic sales team focused on driving RV sales through innovative marketing, exceptional customer service, and effective inventory management while fostering a high-performance...
1 week ago
Embedded Payments Onboarding Manager
$81K - $95K *
Champion the onboarding journey for embedded payment partners by managing cross-functional teams and ensuring compliance. Enhance processes and mentor your team while delivering seamless, scalable, an...
Reposted 1 week ago
$150K - $200K *
Champion the resolution of complex technical issues for clients, leveraging expertise in Linux, networking, and cloud environments. Collaborate with teams to enhance service delivery and operational c...
1 week ago
Post-acute Wound Healing Specialist (Seattle North area)
$104K - $144K *
Unlock potential by serving as a consultative wound care expert, educating clinicians, driving product adoption, and managing accounts to enhance patient healing and business growth in a dynamic healt...
1 week ago
$95K - $115K *
Unlock your potential by developing innovative software solutions using C#, .NET, and Azure. Collaborate with cross-functional teams to enhance business operations and drive technology initiatives tha...
1 week ago
Pharmacist, Home Infusion - Evernorth - Hybrid or Remote
$112K - $189K *
Join us to ensure safe, effective medication therapy while advancing pharmaceutical care. Collaborate with healthcare teams, educate future practitioners, and support drug-related research to optimize...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.