Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$83K - $138K *

Join our team as a Senior Revenue Accountant to enhance global revenue assurance, ensuring compliance with ASC 606 while collaborating with cross-functional teams to drive operational consistency and...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$118K - $166K *

Unlock potential by leveraging data science and AI to drive innovative solutions in marketing and commercial strategies, collaborating with cross-functional teams to transform complex challenges into...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$95K - $115K *

Accelerate business growth by identifying and acquiring new clients while nurturing existing relationships. Collaborate with leaders to enhance revenue strategies and ensure client satisfaction across...

St. Louis, MORemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Join a team that's driving growth by identifying and acquiring new clients while nurturing existing relationships to enhance service alignment and satisfaction across the Midwest region...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Join a team that's dedicated to excellence in food service management, overseeing multiple contracted services with a revenue range of $2-15M+. Lead operations, enhance client relationships, and drive...

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$165K - $265K *

Champion governance excellence by leading policy frameworks, enhancing Board operations, and driving AI-enabled improvements. Engage with investors and committees to elevate governance practices at a...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$80K - $95K *

Unlock potential by serving as the strategic lead for lifestyle accounts. Collaborate with diverse teams to drive marketing success through comprehensive performance insights and effective communicati...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$101K - $131K *

Champion financial integrity in reinsurance programs while leading a collaborative team. Utilize your expertise to ensure accurate financial transactions, resolve discrepancies, and foster continuous...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$108K - $130K *

Lead the architecture and integration of SAP SuccessFactors, overseeing all modules to enhance HR operations. Collaborate with cross-functional teams to ensure compliance, data integrity, and optimal...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$88K - $105K *

Lead strategic initiatives for lifestyle accounts, optimizing multi-channel performance and driving client growth. Utilize data-driven insights to enhance client relationships and ensure marketing ali...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $185K *

Join a team that's redefining the SaaS landscape by driving strategic growth and closing high-value deals. Engage with senior leaders, develop a robust pipeline, and collaborate cross-functionally to...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Media

$204K - $254K *

Lead technical engagements with customers, driving product success through demos, presentations, and collaboration with sales. Contribute to a high-growth team focused on innovative solutions and cust...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $200K *

Manage advanced product development programs for data center infrastructure, collaborating with cross-functional teams to drive comprehensive manufacturing strategies, optimize operations, and ensure...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$82K - $110K *

Grow your career with a dynamic role leading event fundraising strategies, managing sponsor relationships, and driving revenue growth through innovative partnerships and collaborative outreach across...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$225K - $418K *

Elevate your career by leading advanced analytics initiatives that drive strategic business decisions and measurable impact. Collaborate with global teams to innovate and implement cutting-edge analyt...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$74K - $96K *

Innovate financial operations by managing day-to-day accounting tasks, ensuring compliance and accuracy. Collaborate cross-functionally to enhance efficiency and lead impactful projects in a dynamic e...

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$71K - $106K *

Shape the future of surgical nursing by providing exceptional patient care in a dynamic operating room environment. Collaborate with a dedicated team to ensure the highest standards of care before, du...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$119K - $142K *

Drive sales strategy and team performance in the Merchant acquiring sector, fostering growth and innovation. Lead, mentor, and develop a high-performing team while managing budgets and enhancing clien...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$129K - $215K *

Transform enterprise IT planning and performance management, aligning technology priorities and investments to drive informed executive decisions and enhance organizational effectiveness across multip...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Engage with customers by providing expert support for digital PCR instruments. Drive installations, training, and troubleshooting while collaborating with sales teams to enhance customer satisfaction...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Empower market growth by driving sales in the Southwest US. Build strong relationships with utility customers, identify opportunities, and execute strategic plans to enhance Terex Utilities' presence...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Engage with key utility customers to drive sales growth and market share. Collaborate with teams to deliver insights and support customer success while managing pricing strategies and fostering strong...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $140K *

Champion EHS compliance by leading initiatives that enhance safety and sustainability. Drive risk management and foster a culture of accountability while collaborating with senior leaders to ensure co...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform EHS compliance by leading initiatives that enhance safety and sustainability. Drive risk management and foster a culture of continuous improvement while collaborating with senior leaders to...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $140K *

Join a team that's transforming tax research by leveraging AI technology. As a key member, you'll design innovative tax workflows, collaborate with clients, and shape product development, all while en...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.