Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Nurse Practitioner or Physician Assistant (Hybrid) - Breast Oncology
$97K - $174K *
Champion patient care in Breast Medical Oncology, providing comprehensive support throughout the cancer journey. Collaborate with a multidisciplinary team to develop treatment plans and enhance patien...
1 week ago
Nurse Anesthetist CRNA - Anesthesiology
$180K - $324K *
Join a team that's expanding its anesthesia practice, providing diverse care across multiple facilities. Collaborate with skilled professionals in a dynamic environment, delivering high-quality anesth...
1 week ago
$95K - $115K *
Drive impactful presale messaging and project management by collaborating with cross-functional teams to craft compelling presentations that resonate with clients and showcase our unique value proposi...
1 week ago
Senior Financial Systems Analyst
$106K - $127K *
Empower finance teams by bridging systems and analysis, enhancing budgeting, forecasting, and reporting processes. Collaborate with stakeholders to translate needs into effective solutions, driving im...
1 week ago
Application Business Analyst III
$76K - $105K *
Lead the charge in optimizing and supporting application implementations, conducting needs assessments, and managing projects to enhance business processes and user experience for healthcare applicati...
1 week ago
Advanced Practice Provider (NP/PA/CNS) – Independence Internal Medicine I
$90K - $110K *
Deliver comprehensive primary and specialty care as an Advanced Practice Provider, collaborating with a healthcare team to enhance patient outcomes. Emphasize health promotion and disease prevention w...
1 week ago
$125K - $150K *
Transform legal practices by overseeing medical malpractice litigation, guiding internal teams, and collaborating with business partners. Leverage your expertise to ensure compliance and provide strat...
1 week ago
$80K - $115K *
Engage with customers to ensure successful onboarding and implementation of solutions. Collaborate across teams to drive value, manage projects, and advocate for customer needs while building trusted...
1 week ago
Head of Client Success, Wellbeing
$265K - $295K *
Unlock potential by leading a global Customer Success team, driving client satisfaction, renewals, and growth in the Wellbeing division. Collaborate with executives to shape strategy and enhance clien...
1 week ago
Account Manager, Health and Wellness
$130K - $140K *
Transform customer relationships and drive growth by identifying upsell opportunities and ensuring satisfaction within our Health and Wellness vertical. Collaborate with teams to advocate for clients...
1 week ago
$95K - $115K *
Lead and develop a high-performing project management team, ensuring operational excellence and customer satisfaction while driving regional business performance through effective project execution an...
1 week ago
$120K - $145K *
Shape the future of consumer litigation by managing complex cases, providing strategic legal guidance, and collaborating with cross-functional teams to achieve effective resolutions while mitigating r...
1 week ago
Strategic Account Director, Retail
$135K - $160K *
Engage with executive buyers to drive new business in retail, leveraging AI solutions. Build trusted relationships, manage complex sales processes, and ensure smooth transitions to post-sale teams whi...
1 week ago
$150K - $180K *
Unlock potential by driving new business with large enterprises, building trusted relationships with executive buyers, and guiding complex sales from discovery to close, while collaborating across tea...
1 week ago
Employee Benefits Senior Account Manager/ Account Executive- Future Opportunities
$80K - $150K *
Unlock potential by connecting with experienced Employee Benefits professionals for future Senior Account Manager and Account Executive roles, focusing on client management, service excellence, and bu...
1 week ago
Branch Operations Supervisor- Commercial Insurance (Remote)
$105K - $125K *
Lead and oversee Account Management teams, ensuring operational excellence and compliance while fostering staff development and enhancing client relationships in a dynamic remote environment...
1 week ago
Commercial Senior Account Manager/ Account Executive- Future Opportunities
$80K - $150K *
Join a team that's shaping the future of commercial insurance by leveraging your expertise in account management and client relations. Collaborate with industry professionals to drive service excellen...
1 week ago
$95K - $115K *
Unlock potential by providing expert legal guidance in government contracting, ensuring compliance and strategic negotiation. Collaborate with stakeholders to navigate complex contracts while safeguar...
1 week ago
Sr. Product Manager, Product Design & User Research, Sophia Learning
$160K - $180K *
Advance our user-centric product vision by leading design and research initiatives. Collaborate with cross-functional teams to integrate AI and enhance learning experiences, ensuring alignment with st...
1 week ago
Assistant Professor (Full-Time), Clinical Psychology, GuidedPath
$67K - $101K *
Contribute to impactful education by mentoring doctoral students and enhancing curriculum. Engage in teaching, governance, and professional service while fostering inclusive learning environments and...
1 week ago
Contracts Manager, Impact Finance & Markets
$80K - $104K *
Drive the full lifecycle of contractual agreements, ensuring compliance and efficiency while collaborating across teams to enhance processes and support organizational goals in a dynamic, remote-frien...
1 week ago
$63K - $111K *
Join a team that's dedicated to enhancing security systems globally. As a Senior Security Technician, you'll install, maintain, and troubleshoot advanced security solutions while mentoring junior staf...
1 week ago
Functional Specialist/Advisor - TS/SCI
$74K - $130K *
Elevate operational efficiency by providing project coordination and logistical support. Collaborate with stakeholders to enhance business continuity, risk management, and process analysis while devel...
1 week ago
Finance Solutions - Digital Revenue Operations – Manager
$99K - $232K *
Champion finance transformation by leading digital revenue operations, enhancing client revenue processes through analysis, implementation, and support while mentoring teams and managing multiple work...
1 week ago
SAP Order to Cash Consultant, Senior Manager
$124K - $280K *
Lead transformative SAP Order to Cash projects, enhancing customer processes and driving effective software adoption while guiding diverse teams through complex challenges and delivering impactful sol...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.