Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Jobs in Missouri

Average Salary in USD

Average Salary: $114,671

Sort By: Relevance

$56K - $111K *

Drive success by cultivating strong relationships with clients to enhance satisfaction, retention, and sales growth. Collaborate with teams to deliver tailored solutions and insights, ensuring a seaml...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$109K - $144K *

Shape the future of essential industries by leveraging IoT solutions to enhance logistics, safety, and efficiency. Work collaboratively to present innovative technical solutions that impact customer s...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$152K - $190K *

Grow by developing strong relationships with mid-sized customers, leveraging Internet of Things solutions to drive impactful outcomes across various sectors, while navigating complex sales processes a...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$72K - $108K *

Join a team that's dedicated to ensuring quality standards and leading projects. You'll provide guidance to staff, identify process improvements, and contribute to a positive work environment while en...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$210K - $250K *

Lead the charge in capital formation and strategic partnerships, driving equity rounds and forging alliances with industry leaders to propel growth and prepare for a public exit in the robotics sector...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Elevate your career by leading a dynamic sales team, training new members, and building lasting client relationships. Utilize your extensive sales experience to implement proven strategies and provide...

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Deliver impactful project management for innovative justice facilities. Lead multiple projects from inception through completion, ensuring safety, budget management, and stakeholder collaboration. Fos...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$98K - $141K *

Drive efficiency and reliability by leading a team of Controls Engineers to enhance regional plant technology and optimize machine processes, ensuring consistent implementation of industry standards a...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $95K *

Partner with us to provide expert field service support for advanced automotive paint shop systems. You'll troubleshoot, optimize, and enhance equipment performance while building strong customer rela...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$152K - $190K *

Champion the future of physical operations by leveraging IoT data to drive business transformation for mid-sized clients. Navigate complex sales processes, engage multiple stakeholders, and educate cu...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $200K *

Engage advisors and drive growth in wealth management products across the Mid-Atlantic. Utilize consultative sales skills, market insight, and relationship management to enhance business outcomes, ens...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Langan is seeking a Senior Site/Civil Project Manager specializing in Data Centers and Critical Facilities to lead design, permitting, and client management efforts for land development projects. This...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Drive exceptional land development projects in data centers. Lead multi-discipline teams, manage client relationships, and ensure successful project execution from concept through completion, empoweri...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$250K - $300K *

Join a team that's dedicated to transforming pain management through compassionate, multimodal care. Collaborate with specialists to enhance patient quality of life and expand access to coordinated se...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$300K - $350K *

Elevate your career by joining a dynamic network of gastroenterology professionals, leveraging strong referral relationships and resources to enhance patient care and expand your practice in a support...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $125K *

Advance business growth by fostering relationships and crafting innovative strategies that drive revenue. Collaborate across teams to identify opportunities and enhance operational excellence while en...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Business Services

$117K - $162K *

Drive financial excellence by overseeing reporting, budgeting, and internal controls at our manufacturing facility. Collaborate across departments to enhance performance and support continuous improve...

6 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$174K - $374K *

Manage clinical oversight and mentorship in a remote role, guiding enterprise-wide medical decisions, reviewing complex cases, and ensuring evidence-based coverage determinations while collaborating a...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$68K - $100K *

Empower patient care by assessing needs, implementing nursing actions, and collaborating with multidisciplinary teams to enhance outcomes in a dynamic ICU environment. Join a dedicated team committed...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$132K - $271K *

Join a team that's driving innovation in software sales by delivering impactful product demonstrations and supporting complex pre-sales processes. Leverage your expertise to enhance client engagement...

6 days ago

  •   8 - 10 years exp.  •   Business Services

$85K - $102K *

Drive manufacturing modernization by leading technical projects, solving complex problems, and enhancing client relationships. Collaborate with teams to develop innovative solutions and ensure project...

6 days ago

  •   Less than 5 years exp.  •   Business Services

$350K *

Engage with key enterprise clients to drive revenue growth through strategic, solution-based sales. Develop lasting relationships and navigate complex sales processes while championing company values...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$222K - $278K *

Reimagine enterprise sales by developing executive relationships and leading customer engagements. Drive revenue growth through strategic deal-making with a focus on customers while embodying core cul...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$73K - $87K *

Unlock potential by driving transformation through emerging technologies. Collaborate with stakeholders to analyze, prototype, and implement AI solutions that address real-world challenges, ensuring h...

6 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$93K - $110K *

Join a team that's dedicated to delivering exceptional project management for restaurant construction. Oversee projects from inception to completion, ensuring client satisfaction and adherence to time...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.