Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Software Product Management Pre Sales Senior Manager - Consumer Goods & Services
$132K - $271K *
Discover innovative solutions by leading pre-sales efforts, delivering tailored product demos, and collaborating with clients and partners to drive successful software sales cycles across diverse indu...
5 days ago
$87K - $293K *
Reimagine retail banking transformation by leading strategic client engagements that integrate business strategy, technology, and operations. Drive innovation and achieve alignment through data and AI...
Reposted 5 days ago
Account Executive Electricity Procurement Lead
$84K - $135K *
Grow your career by delivering tailored energy solutions to commercial clients. Utilize your sales expertise in the deregulated market while cultivating long-term partnerships and engaging with divers...
Reposted 5 days ago
Blockchain Security Expert - Anti Defect Track
$90K - $150K *
Shape the future of cybersecurity by identifying vulnerabilities in blockchain smart contracts. Collaborate on security audits, enhance tools, and embrace emerging technologies to bolster security sol...
Reposted 5 days ago
Pediatric Dentist - St. Louis Children's Hospital in St. Louis, MO
$150K - $180K *
Champion pediatric dental care by diagnosing, treating, and educating patients. Collaborate with a dedicated team to manage complex cases and ensure optimal health outcomes for children in both outpat...
5 days ago
Project Manager - Construction
$80K - $95K *
Elevate your career by managing diverse capital improvement projects, serving as a trusted advisor throughout the project lifecycle, and ensuring exceptional client service while meeting scope, budget...
Reposted 5 days ago
Senior Security Engineer - Threat Detection
$157K - $238K *
Pioneer innovative threat detection engineering solutions that protect our infrastructure. Collaborate across teams to enhance our detection platform through advanced telemetry, improve pipeline relia...
Reposted 5 days ago
$90K - $120K *
Optimize client financial systems by implementing tailored processes, managing teams, and providing strategic support to dynamic startups. Engage with diverse clients, ensuring effective communication...
Reposted 5 days ago
$125K - $170K *
Champion pricing strategies for complex public-sector contracts, leading cost model development and commercial analysis. Collaborate with cross-functional teams to ensure compliance and competitivenes...
5 days ago
$125K - $150K *
Shape the future of affordable housing by managing LIHTC transactions from underwriting to closing. Collaborate with developers and investors to ensure timely execution and sound investment recommenda...
5 days ago
Manager, GPO Delivery & Optimization
$90K - $150K *
Drive contract delivery and optimization for member accounts, ensuring value realization through data analysis and cross-functional collaboration. Manage project execution, stakeholder engagement, and...
5 days ago
Senior Cybersecurity Architect (Cloud)
$150K - $165K *
Join a dynamic team to design and implement robust cloud security solutions across diverse environments, ensuring safe adoption of AI and compliance with regulatory standards while leading technical i...
5 days ago
Cybersecurity Engineer (Cloud)
$130K - $140K *
Lead the charge in implementing robust cloud security controls across diverse environments, ensuring compliance with regulatory frameworks while enabling safe adoption of AI technologies. Collaborate...
5 days ago
$90K - $120K *
Transform procurement operations by managing supplier relationships and sourcing strategies within IT categories. Drive cost savings and quality improvements while ensuring compliance and operational...
5 days ago
Sr. Strategic Sales Manager- Western Ohio & Indiana
$112K - $143K *
Drive new business opportunities in B2B payments by leveraging your consultative sales expertise. Manage the complete sales cycle, build strong client relationships, and optimize payment solutions for...
5 days ago
Bilingual (English/Spanish) Transitions of Care RN Case Manager
$85K - $100K *
Lead the charge in providing telephonic care management for high-risk patients post-discharge, ensuring they receive essential resources and support for improved health outcomes while collaborating wi...
5 days ago
Transitions of Care RN Case Manager
$85K - $100K *
Elevate patient care by providing telephonic case management for high-risk individuals post-discharge. Advocate for patients, coordinate resources, and develop personalized care plans to enhance healt...
5 days ago
Portfolio Manager - Commerce Trust
$137K - $214K *
Engage with clients to manage investment portfolios, ensuring alignment with financial goals through strategic asset allocation and performance reporting while collaborating with a dedicated team of w...
5 days ago
Vice President, Executive Planning Consultant - Lakes Region
$96K - $210K *
Shape the future of financial planning by serving as a trusted advisor to senior executives, providing tailored investment strategies and comprehensive financial guidance to enhance their financial we...
5 days ago
Research Project Manager, Pediatrics
$66K - $96K *
Join a dynamic team to oversee and manage innovative research studies, ensuring protocol design, project operations, and compliance. Collaborate with experts to drive scientific objectives and enhance...
5 days ago
FLIGHT DECK Capability Building Partner
$122K - $155K *
Elevate capability development by designing and delivering impactful learning solutions. Collaborate with stakeholders to enhance performance and drive measurable outcomes across a global organization...
Reposted 5 days ago
Lead Supplier Quality Engineer - Metallic Powders & Melting
$95K - $115K *
Champion supplier quality improvement in aerospace by leveraging expertise in melting, conversion, and forging processes. Drive supplier audits, implement quality plans, and enhance performance throug...
5 days ago
Lead Supplier Quality Engineer - Forgings & Materials
$100K - $133K *
Join a team that's dedicated to enhancing supplier quality in aerospace. Leverage your expertise in forgings to implement quality plans, drive compliance, and lead audits, ensuring excellence across s...
5 days ago
Capital One Shopping Tech, Data Engineer 5 (Remote- Eligible)
$209K - $238K *
Engineer transformative data solutions by collaborating across Agile teams, leveraging cutting-edge technologies, and driving impactful initiatives that empower millions. Elevate your career while sha...
5 days ago
$75K - $158K *
Champion the design and optimization of SAP Forms solutions to enhance logistics and financial operations within a complex SAP S/4HANA environment, collaborating with stakeholders to drive efficiency...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.