Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Senior Advanced IT Network Site Reliability Engineer
$139K - $151K *
Join a team that's pushing the boundaries of advanced technologies. Lead initiatives in network infrastructure, implementing and troubleshooting solutions that support critical missions across various...
5 days ago
Senior Hydrogeologist, Groundwater Modeler
$95K - $115K *
Join us in shaping the future of groundwater management and remediation. As a Senior Hydrogeologist, you'll lead innovative projects, provide expert analysis, and drive client success while managing c...
5 days ago
Practice Leader - Environmental Remediation Geologist or Engineer
$110K - $130K *
Transform your career by leading innovative environmental remediation projects. Drive business development, manage complex site investigations, and mentor junior staff while collaborating with diverse...
5 days ago
Physician Leadership Opportunity - Value Based Primary Care
$260K - $285K *
Transform healthcare delivery by leading a clinical pod team, ensuring quality patient care, safety, and team collaboration. Drive performance metrics and foster relationships with clinical staff to e...
5 days ago
$104K - $166K *
Lead the administration and support of IBM MQ environments in a complex enterprise banking setting. Utilize your expertise in Unix/Linux systems to ensure high availability and reliability of messagin...
5 days ago
Technical Enterprise Incident Manager
$86K - $138K *
Champion incident management by leading rapid response efforts, ensuring service restoration and implementing ITIL best practices to enhance operational excellence across cloud technologies and applic...
Reposted 5 days ago
$104K - $166K *
Unlock your potential as a Senior IBM MQ Administrator, managing complex enterprise banking environments. Leverage your expertise in IBM MQ, Unix/Linux systems, and troubleshooting to ensure high avai...
5 days ago
$90K - $113K *
Take ownership of contract administration for government and commercial agreements. Collaborate cross-functionally to ensure compliance, manage risks, and drive process improvements while supporting t...
5 days ago
$120K - $140K *
Elevate financial integrity by leading month-end and year-end closes, ensuring compliance with US GAAP. Collaborate across teams to enhance reporting accuracy and streamline processes, driving operati...
5 days ago
$120K - $145K *
Join a dynamic team as you drive product strategy and AI integration, ensuring innovative solutions meet market needs. Collaborate cross-functionally to enhance user experiences and deliver high-value...
5 days ago
Business Development Associate – Air Force
$80K - $95K *
Accelerate growth by identifying and capturing new business opportunities within the U.S. Air Force. Collaborate with stakeholders to develop strategies, manage pipelines, and support proposals, ensur...
5 days ago
Army Business Development Associate
$80K - $95K *
Innovate within a dynamic team to drive growth by identifying and developing new business opportunities in the Dept of Army sector. Leverage relationships and market insights to shape a robust portfol...
5 days ago
$120K - $165K *
Unlock potential by harnessing your expertise as a Senior .NET Developer, driving the evolution of high-availability applications in a cloud-native environment, leading projects, mentoring teams, and...
Reposted 5 days ago
Director, GPO Strategic Accounts Specialty Pharmacy/Payer Account Management
$142K - $177K *
Drive strategic growth by managing high-impact relationships with health systems and specialty pharmacies. Lead account management, enhance client satisfaction, and identify opportunities for value ex...
5 days ago
$101K - $204K *
Unlock potential by leading agile teams to design, develop, and maintain complex software systems. Mentor junior engineers while driving innovative solutions and ensuring high-quality deliverables acr...
5 days ago
Senior Total Rewards & HR Analytics Specialist - Remote
$103K - $193K *
Unlock potential by enhancing compensation programs and delivering insightful HR analytics. Collaborate with cross-functional teams to ensure equitable, compliant, and data-driven total rewards practi...
5 days ago
Senior VA Health Systems Integration & Interoperability Specialist
$125K - $200K *
Drive VA health systems integration by leading complex interoperability initiatives, ensuring seamless data flow across clinical and community care platforms to enhance Veteran care and operational ef...
5 days ago
Data Platform Engineer (Army Vantage) - Clearance Required
$130K - $170K *
Lead the development of innovative data solutions, integrating AI/ML capabilities and optimizing data pipelines within Palantir Foundry and Databricks. Collaborate with cross-functional teams to enhan...
5 days ago
Atlassian Instructional Designer Level III
$85K - $115K *
Transform learning experiences by designing role-based training for Agile practices and Atlassian tools. Leverage your expertise in instructional design to create engaging, accessible content that mee...
5 days ago
Agile Coach / Trainer Level IV
$102K - $174K *
Advance Agile delivery practices and Atlassian tool proficiency by coaching teams, leading workshops, and tailoring instruction to enhance effectiveness across a distributed workforce. Drive sustainab...
5 days ago
Full Stack Software Engineer - Clearance Required
$111K - $192K *
Engage in full-stack software development, collaborating with teams to enhance features and performance. Utilize modern technologies to build secure, scalable applications for military and government...
5 days ago
Senior Project Manager / SCRUM Master
$111K - $192K *
Unlock potential by leading Agile delivery for technology modernization initiatives. Drive project planning, stakeholder coordination, and disciplined management to ensure multidisciplinary teams achi...
5 days ago
Change & Communications Specialist III
$76K - $130K *
Join a team that's driving change by leading stakeholder engagement and adoption of Agile practices and Atlassian tools. This role blends communication strategy and organizational change management to...
5 days ago
Complex Claims Specialist, Miscellaneous Medical Facilities Professional Liability
$95K - $115K *
Empower our team by managing complex medical professional liability claims. Utilize your expertise to shape strategies, coordinate resources, and influence outcomes in a collaborative environment whil...
5 days ago
Senior Claims Specialist, Miscellaneous Medical Facilities & Long-Term Care Professional Liability
$88K - $105K *
Empower a dynamic team by managing MMF/LTC Professional Liability claims, conducting thorough investigations, and ensuring timely resolutions while adhering to authority limits and litigation guidelin...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.