Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
$120K - $145K *
Take ownership of MES initiatives, driving technical leadership and integration in life sciences manufacturing. Collaborate across teams to optimize systems, ensuring compliance and reliability in a r...
5 days ago
(Remote) Cyber Vulnerability Assessment Analyst Senior - Cyber Security
$108K - $130K *
Join a team that's dedicated to enhancing cybersecurity by assessing vulnerabilities across enterprise systems and guiding remediation efforts. This senior role offers mentorship opportunities while d...
Reposted 5 days ago
Business Development Executive
$100K - $120K *
Accelerate progress at managing key client accounts with a data-driven approach. Develop tailored strategies that align with client goals while collaborating with cross-functional teams to drive growt...
5 days ago
$83K - $100K *
Champion life-saving missions as a skilled pilot, delivering critical care with precision and commitment. Join a dedicated team operating in diverse environments, where your expertise can profoundly i...
5 days ago
$83K - $100K *
Join our elite team of pilots to deliver critical care in life-saving missions. Experience the thrill of aviation while making a profound impact on patients' futures in diverse environments. Elevate y...
5 days ago
$75K - $90K *
Champion life-saving missions as a skilled pilot, delivering critical care with precision and commitment. Join a dedicated team operating in diverse environments, ensuring rapid medical response and m...
5 days ago
Product Installation Engineer - SPTS - 90% Travel. Ft Collins Colorado based
$70K - $119K *
Pioneer excellence in service delivery by independently installing advanced tools and ensuring optimal performance through expert troubleshooting and customer support. Drive metrics and report outcome...
Reposted 5 days ago
Enterprise Account Executive, Major Accounts - West
$135K - $203K *
Unlock potential by driving growth and retention for large automotive dealer groups. Leverage a consultative sales approach to connect solutions with measurable outcomes, ensuring long-term value and...
5 days ago
Competitive Intelligence Specialist
$150K - $175K *
Optimize competitive strategies and market insights as a key player in our International Business Development team. Analyze trends, synthesize intelligence, and empower decision-making to enhance our...
5 days ago
$190K - $305K *
Shape the HCP marketing strategy by developing integrated plans that resonate with healthcare professionals, driving engagement and business growth through targeted outreach and data-driven insights...
5 days ago
$95K - $115K *
Engage early to maximize competitive advantage by overseeing the bid and proposal process. Collaborate with cross-functional teams to develop winning proposals, ensuring high quality and compliance wh...
5 days ago
Trades Sales Specialist - San Francisco, CA
$100K - $162K *
Elevate your career by driving sales growth in the commercial construction sector. Build strong relationships with end-users, mentor teams, and implement marketing strategies while utilizing CRM tools...
5 days ago
Strategic Business Consultant (Retirement Sales)
$100K - $120K *
Analyze client relationships to enhance service and drive growth for elite advisors and TPAs. Collaborate with internal teams to deliver strategic solutions and ensure a premier client experience, all...
Reposted 5 days ago
Global Campus Professor - Department of Financial Operations (Remote)
$75K - $120K *
Champion exceptional learning experiences through innovative teaching and mentorship. Engage with adult learners in online courses, lead curriculum development, and foster a supportive academic commun...
5 days ago
Regional Sales Manager - Midwest
$110K - $130K *
Lead the charge in driving capital sales for advanced medical technology, focusing on CyberKnife and Radixact systems. Engage with C-suite stakeholders and navigate complex sales cycles to achieve reg...
5 days ago
Install Base Sales Manager - West
$110K - $130K *
Drive growth and maximize customer value by enhancing software adoption, expanding service revenue, and fostering long-term relationships within the installed base of clinical technologies in a dynami...
5 days ago
Enterprise Risk Management Data Analytics Lead
$156K - $181K *
Elevate enterprise risk management by designing and executing data analytics solutions. Collaborate with stakeholders to enhance reporting processes and deliver insights that drive strategic decision...
5 days ago
Senior Risk Management Associate
$123K - $142K *
Lead the execution of Enterprise Risk Management programs, collaborating across teams to enhance risk governance and training initiatives. Drive project management efforts, ensuring timely delivery an...
5 days ago
Governance, Risk and Compliance Lead
$132K - $156K *
Unlock potential by leading governance, risk, and compliance initiatives. Collaborate with cross-functional teams to optimize processes, manage projects, and enhance training programs while ensuring e...
5 days ago
Senior Analyst - Strategy, Analytics & Reporting
$109K - $125K *
Unlock potential by transforming complex data into actionable insights that drive enterprise strategy and decision-making. Collaborate across teams to develop reporting tools and metrics that enhance...
5 days ago
Senior Technical Product Manager - APIs & Integrations
$130K - $180K *
Drive the vision and strategy for API and integration products, ensuring seamless connectivity across systems. Collaborate with cross-functional teams to deliver innovative solutions that enhance cust...
5 days ago
Legal Project Manager, Employment Litigation & Discovery
$95K - $115K *
Lead the charge in managing complex employment litigation and discovery processes. Collaborate with cross-functional teams to ensure timely, high-quality results while enhancing legal project manageme...
5 days ago
$72K - $111K *
Join the charge in managing DoD property and IT assets, ensuring compliance with regulations and maintaining accurate records throughout their lifecycle. Collaborate with cross-functional teams to sup...
5 days ago
Advanced Software Engineer - AI Reliability Engineering
$118K - $131K *
Optimize your career by joining a dynamic team that develops cutting-edge AI-native solutions. Engage in full software development lifecycle, collaborating with users to create impactful technologies...
5 days ago
Senior M365 / Power Platform Developer
$132K - $143K *
Shape the future of digital solutions by developing innovative M365 and Power Platform applications. Collaborate with a dynamic team to enhance enterprise collaboration, automate processes, and levera...
Reposted 5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.