Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Strategic Accounts Customer Success Manager (CSM IC)
$140K - $190K *
The Strategic Accounts Senior Customer Success Manager at Motive will serve as the primary contact for the company's largest customers, ensuring their successful implementation and ongoing satisfactio...
Reposted 5 days ago
$106K - $120K *
Transform enrollment operations by leading a dynamic team, optimizing processes, and driving performance improvements across multiple companies to enhance efficiency and compliance in a remote environ...
5 days ago
Client Onboarding Manager (Finance & Accounting Outsourcing)
$101K - $192K *
Oversee the onboarding of new clients for outsourced accounting services, managing relationships and leading teams to ensure timely financial reporting and exceptional service delivery while driving p...
Reposted 5 days ago
$104K - $130K *
Contribute to ICT design and project management for mission-critical data centers and smart buildings. Collaborate with technical teams, manage project scopes, and utilize advanced tools to enhance ef...
5 days ago
$110K - $130K *
Transform data into actionable insights by mastering analytics across diverse domains. Collaborate with cross-functional teams to optimize reporting workflows and drive impactful solutions in a fast-p...
5 days ago
Sr Director, Global Total Rewards
$160K - $200K *
Lead the charge in shaping global total rewards strategies, enhancing compensation, benefits, and HR systems for a diverse workforce. Collaborate with executives and drive initiatives that attract top...
5 days ago
Senior Manager, Product Marketing
$125K - $150K *
Lead the charge in shaping product marketing strategies that resonate with customers. Drive market positioning, product development, and sales enablement while collaborating across teams to enhance cu...
5 days ago
$70K - $97K *
Champion operational excellence and drive sales as you lead a dynamic team to enhance customer experiences and achieve financial goals. Your leadership will foster a high-performance culture focused o...
5 days ago
$160K - $220K *
Elevate your career by leading the design and deployment of innovative AI solutions. Collaborate with strategic customers to tackle complex data challenges, leveraging graph databases and LLMs to deli...
5 days ago
$200K - $400K *
Unlock your potential as a strategic leader, driving enterprise account growth and fostering deep client relationships. Collaborate cross-functionally to align commercial strategies with client object...
Reposted 5 days ago
Principal Fraud Analyst (Data Science), Digital Payments Fraud Strategy US
$128K - $205K *
Drive the analytical strategy for fraud risk mitigation in digital transactions. Collaborate with cross-functional teams to develop metrics and frameworks that enhance decision-making and risk detecti...
5 days ago
$110K - $130K *
Empower financial excellence by overseeing accounting operations, ensuring compliance with GAAP, and driving efficient month-end close processes. Collaborate with teams to enhance accounting practices...
5 days ago
$80K - $95K *
Lead audit operations by managing team performance, driving process improvements, and ensuring compliance. Collaborate with IT and offshore teams to enhance efficiency and client satisfaction while ov...
5 days ago
Chief Compliance Officer (CCO) - US
$200K - $280K *
Shape the future of compliance by architecting a robust regulatory framework for a dynamic investment platform. Collaborate with stakeholders to ensure adherence to SEC standards while enabling growth...
5 days ago
$125K - $150K *
Transform enterprise data governance by leading strategy, enhancing quality, and ensuring responsible use. Collaborate with senior leaders to integrate governance into priorities and drive measurable...
5 days ago
Product Manager, Therapy Services Operations
$108K - $135K *
Join a team that's driving innovation and operational excellence in digital services. This role involves project management, cross-functional collaboration, and strategic execution to ensure successfu...
5 days ago
$160K - $195K *
Partner with us to drive enterprise growth by managing client relationships, aligning strategies, and maximizing value across accounts. Lead cross-functional teams to deliver exceptional outcomes and...
5 days ago
Clinical Implementation Specialist
$95K - $115K *
Shape the future of clinical software solutions by leading technical implementations, ensuring client needs are met through expert guidance and innovative design practices. Collaborate with teams to e...
5 days ago
Senior Director, Product Growth
$275K - $300K *
Champion product growth by defining activation metrics and driving member engagement across diverse health solutions. Lead a cross-functional team to enhance user retention and optimize product strate...
5 days ago
Grad Intern - Amgen Library (Summer 2027)
$73K - $87K *
Inspire innovation and collaboration as you support library resources and projects. Engage in experiential learning while maintaining accurate records and resolving access issues, contributing to impa...
5 days ago
Mechanical Automation Specialist
$80K - $95K *
Unlock your potential as you enhance manufacturing operations through automation expertise. Collaborate with cross-functional teams to drive reliability, safety, and productivity improvements in packa...
5 days ago
$84K - $105K *
Contribute to impactful communications by crafting compelling press releases, executive content, and internal messages. Collaborate with senior leaders and adapt narratives for diverse audiences while...
5 days ago
$125K - $150K *
Drive data excellence by establishing standards and insights that enhance operational decisions. Collaborate across teams to automate processes, improve data quality, and deliver actionable insights t...
5 days ago
P&C Product Management Director - State Management
$127K - $243K *
Lead the charge in driving P&C product strategy and growth across the Northeast, leveraging data analytics and market insights to enhance profitability and market share while collaborating with stakeh...
5 days ago
$100K - $120K *
Empower your career by ensuring quality assurance and training for DRG Reviewers. Contribute to improving clinical documentation and auditing processes while fostering an environment of continuous lea...
Reposted 5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.