Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Average Salary: $114,671
Director, Payment Integrity (Analytics & Strategy) - REMOTE
$125K - $150K *
Inspire a culture of payment integrity by leading strategic development and team performance. Drive continuous improvement initiatives while optimizing operational objectives to enhance healthcare com...
Reposted 5 days ago
Oracle E-Business Suite Solution Architect - Fit-Gap Discovery Lead
$150K - $180K *
Explore innovative solutions as you lead fit-gap discovery engagements, guiding clients through their transition to Oracle E-Business Suite while collaborating with cross-functional teams to ensure se...
5 days ago
In-Field Sales Training Manager | 1099 | $90,000+
$90K - $300K *
Lead the charge in training and coaching Sales Advisors in the field, enhancing their skills in prospecting, inspections, and closing deals while ensuring a top-notch customer experience and achieving...
5 days ago
Sr. Manager Financial Planning & Analysis
$110K - $130K *
Accelerate your career as a Sr. FP&A Manager, driving financial insights and strategic decision-making across SaaS and payments sectors. Collaborate with leadership and leverage AI tools to enhance op...
5 days ago
Senior Lead Electrical Engineer, Datacenter
$160K - $230K *
Deliver advanced electrical engineering solutions for hyperscale data centers. Lead design teams, oversee project execution, and ensure compliance with industry standards while fostering client relati...
5 days ago
Workday Financials Senior Principal Consultant, Record to Report - Global AMS
$128K - $192K *
The Workday Financials Senior Principal Consultant, Record to Report is a dynamic professional responsible for leading the Financials workstream and ensuring operational efficiency in Workday engageme...
Reposted 5 days ago
Nurse Practitioner - PEDS Otolaryngology
$97K - $174K *
Unlock potential by joining a dedicated Pediatric ENT team, providing specialized care to children in an outpatient setting. Collaborate with top specialists while enjoying professional growth opportu...
5 days ago
Product Manager, Toast IQ Evaluation
$159K - $254K *
Engineer a transformative AI-powered Customer Success platform, driving proactive support and growth for restaurants. This high-impact role blends product strategy with AI innovation, ensuring lasting...
Reposted 5 days ago
$80K - $131K *
Lead the charge in engineering excellence for a Salesforce CRM platform. Oversee a team of engineers, ensuring high-quality technical execution, platform reliability, and effective collaboration acros...
5 days ago
Staff Regional Marketing Manager, West
$139K - $235K *
Drive regional marketing initiatives that accelerate pipeline growth. Own strategy and execution for campaigns and events, collaborating with sales teams and partners to achieve measurable results whi...
5 days ago
Principal Client Success Manager, Payer
$113K - $164K *
Lead the charge in enhancing client success by strategically advising high-impact clients, fostering executive relationships, and driving solution adoption while mitigating risks and ensuring measurab...
5 days ago
Senior Program Manager - Data Center Construction
$110K - $130K *
Take ownership of large-scale construction projects, managing stakeholders and ensuring compliance. Oversee project governance, track milestones, and enhance processes while fostering client relations...
5 days ago
$110K - $130K *
Transform customer support by leading a high-impact team focused on quality, efficiency, and satisfaction across all channels. Drive strategic initiatives, develop talent, and enhance processes to ens...
5 days ago
Oracle EBS Manufacturing Functional Analyst (WIP & Quality)
$95K - $115K *
Accelerate progress at the intersection of engineering and Oracle systems, providing immediate solutions for production challenges. Own functional support for Oracle WIP, troubleshoot quality plans, a...
5 days ago
Staff Engineer, Application Security (Remote, US)
$170K - $220K *
Oversee and enhance security strategies across applications, cloud, and AI systems. Lead initiatives to mitigate risks, improve security architecture, and foster a culture of security within engineeri...
5 days ago
$100K - $120K *
Optimize talent acquisition by sourcing top candidates for technical roles. Collaborate closely with clients to understand their culture and needs, ensuring a seamless recruitment process that enhance...
5 days ago
Senior Software Engineer, Developer Enablement
$120K - $145K *
Join a team that's dedicated to enhancing developer experience by building reliable APIs and tools. Collaborate with cross-functional teams to deliver high-quality software solutions that empower cust...
5 days ago
Staff Engineer, Manufacturing Engineering
$108K - $130K *
Elevate manufacturing excellence by providing technical leadership in complex processes, enhancing production efficiency, and implementing advanced technologies while collaborating across functions to...
5 days ago
$90K - $119K *
Optimize compliance and risk management by conducting thorough audits, collaborating cross-functionally, and driving continuous improvement in adherence to regulatory standards and operational practic...
5 days ago
Regional Sales Manager - US South Central - Remote
$110K - $150K *
Lead the charge in driving revenue growth by developing new business opportunities and managing client relationships in the robotics and automation sectors, while collaborating with technical teams to...
5 days ago
Fullstack Software Engineer (Frontend Focused)
$125K - $150K *
Join a team that's redefining mental health technology by developing a cutting-edge brain stimulator platform. Lead fullstack development, enhance user experience, and mentor a talented engineering te...
5 days ago
National Account Executive, Employee Benefits
$121K - $152K *
Shape the future of employee benefits by delivering strategic account management and innovative solutions that drive client growth and retention while fostering impactful partnerships with national ac...
Reposted 5 days ago
$143K - $169K *
Drive strategic revenue forecasting and reporting for hardware, collaborating with cross-functional teams to enhance decision-making and insights. Engage with executive leadership to shape narratives...
5 days ago
Senior Software Engineer, Distributed Systems - NIM Factory
$184K - $287K *
Innovate scalable factory infrastructure for AI model deployment, enhancing performance and reliability across diverse environments. Collaborate with teams to drive technical advancements and streamli...
5 days ago
$150K - $180K *
Accelerate progress at a dynamic organization by leading a talented engineering team. Drive innovation in AI-assisted software development for healthcare solutions, ensuring quality, security, and ope...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.